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Tissue-specific blood stem cell line established from embryonic stem cells

A research team at the Umea Center for Molecular Medicine (UCMM) in Sweden, led by Professor Leif Carlsson, has managed to specifically establish and isolate the tissue-specific stem cell that produces blood cells (blood stem cell) by using genetically modified embryonic stem cells.

28 Apr 2008

Man's sight restored by gene therapy

Eye specialists at London's Moorfields Eye Hospital in Britain have restored a man's sight by using gene therapy.

28 Apr 2008

Smokers more prone to depression

Researchers in Spain suggest that smokers are significantly more at risk of suffering depression than non-smokers.

28 Apr 2008

Survey suggests 65% of women in the U.S. could have an eating disorder

Researchers in the U.S. have discovered that as many as 65 percent of women between the ages of 25 to 45, have some form of eating disorder and another 10 percent admit to having eating disorders such as anorexia and bulimia nervosa or binge eating.

28 Apr 2008

Gene therapy restores vision in patients with rare congenital blindness

In a clinical trial at The Children's Hospital of Philadelphia, researchers from The University of Pennsylvania have used gene therapy to safely restore vision in three young adults with a rare form of congenital blindness.

27 Apr 2008

Minimally invasive heart bypass surgery using a DaVinci robot provides health and economic benefits

Minimally invasive heart bypass surgery using a DaVinci robot means a shorter hospital stay and faster recovery for patients, as well as fewer complications and a better chance that the new bypass vessels will stay open.

27 Apr 2008

3D view of neurons provided by new technique

A new technique that marries a fast-moving laser beam with a special microscope that look at tissues in different optical planes will enable scientists to get a three-dimensional view of neurons or nerve cells as they interact, said Baylor College of Medicine scientists in a report that appears in the journal Nature Neuroscience.

27 Apr 2008

Epigenetic research uncovers new targets for modification enzymes

Enzymes regulating genetic expression can be just as important as the genome itself, increasing evidence shows.

27 Apr 2008

Discovery of important markers of high risk of type 2 diabetes

Doctors are aware of a range of risk factors, mostly related to the patients' family history, overweight, and lifestyle, that contribute to the risk of developing type 2 diabetes.

26 Apr 2008

Adult participants needed for ADHD study

The Indiana University School of Medicine Department of Psychiatry seeks participants for a study on the effectiveness of an investigational medication for adults with Attention Deficit-Hyperactivity Disorder. The research study also will examine the impact of adult ADHD on families.

26 Apr 2008

Democratic lawmakers set smaller goals for health care than Presidential candidates' proposals

Democratic lawmakers are "maneuvering to lower public expectations" about the prospects of health care proposals offered by Democratic presidential candidates Sens. Hillary Rodham Clinton (N.Y.) and Barack Obama (Ill.) amid concerns that "sweeping change will be difficult," The Hill reports.

24 Apr 2008

Bioartificial kidney speeds recovery, reduces mortality

Another promising clinical trial for the bioartificial kidney is offering researchers even more hope that within the next few years the device will be available to save lives of patients with acute renal failure.

24 Apr 2008

Self-referring physicians behind increase in diagnostic imaging

Physicians who refer patients to their own facilities or machines for scans account for much of the increase in diagnostic imaging ordered for privately insured patients said a Baylor College of Medicine expert in a commentary that appears in the current issue of the journal Medical Care.

24 Apr 2008

Researchers identify Heme detoxification protein - potential target for developing new malaria drugs

Researchers at the Virginia Bioinformatics Institute (VBI) at Virginia Tech have identified Heme Detoxification Protein (HDP), a unique protein encoded in the malaria genome that represents a potential target for developing new malaria drugs.

24 Apr 2008

Pralatrexate for T-cell lymphoma

The fifth leading cause of cancer in the United States, lymphoma is made up of more than 40 rare and highly diverse diseases that target the body's lymphatic system. Lymphomas include both one of the fastest growing cancers -- Burkitt's lymphoma, which can double in size in as little as a day -- and one of the slowest, chronic lymphocytic leukemia (CLL).

24 Apr 2008

AMPK signaling helps explain how cell growth is inhibited when nutrients are low

A team of scientists at the Salk Institute for Biological Studies think they know how many-if not most-living organisms answer this question. They recently showed that when food supplies dwindle, mammals, fruitflies, or frogs probably activate the same ancient cell signaling pathway in order to conserve energy.

24 Apr 2008

Hepatitis C therapy peginterferon alfa-2b shows promise

The hepatitis C therapy peginterferon alfa-2b, when given as low-dose maintenance therapy, can prevent disease progression in certain patients who failed previous interferon-based hepatitis C therapies and have advanced liver disease, according to findings from a large, four-year study presented today at the 43rd annual meeting of the European Association for the Study of the Liver (EASL).

24 Apr 2008

Mitochondrial dysfunction and redox signaling in atrial tachyarrhythmia

Researchers at the University Hospital of Magdeburg (Germany) have discovered that atrial tachycardia is associated with mitochondrial dysfunction and oxidative stress followed by the activation of the NF-kB signalling pathway with induction of NF-kB target gene expression in atrial tissue.

24 Apr 2008

New 3-D ultrasound provides clear images of the major arteries within the brain

Using 3-D ultrasound technology they designed, Duke University bioengineers can compensate for the thickness and unevenness of the skull to see in real-time the arteries within the brain that most often clog up and cause strokes.

24 Apr 2008

Beta arrestins found to generate new proteins

Duke University Medical Center researchers have recently discovered that a crucial communications pathway in cells not only stops cells from making proteins, it also makes them go. The team was able to define the way in which proteins called beta arrestins (for their role in stopping signals) also turn on pathways that ultimately lead to the production of new proteins in virtually all tissues in the body.

24 Apr 2008