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Clinical trials aim to repair bones using adult stem cells combined with biomaterials

The clinical trials aim to repair bones using adult stem cells combined with biomaterials. It will be conducted in France in the Cr-teil University Hospital Centre and the Regional University Hospital Centre in Tours, in collaboration with the French Blood Establishment.

10 Jan 2013

Leptin hormone also regulates airway diameter

A new study led by Columbia University Medical Center (CUMC) researchers has found that leptin, a hormone that plays a key role in energy metabolism, fertility, and bone mass, also regulates airway diameter.

9 Jan 2013

CTI initiates enrollment in pacritinib Phase 3 trial for myelofibrosis

Cell Therapeutics, Inc. (CTI) today announced that the Company has initiated clinical trial sites and began enrolling patients in a Phase 3 clinical trial, known as PERSIST-1 or PAC325, for pacritinib, CTI's investigational JAK2 inhibitor, which is being evaluated for the treatment of patients with myelofibrosis.

9 Jan 2013

Key link between stem cell factors that fuel ovarian cancer's growth and patient prognosis

Researchers at Yale School of Medicine have identified a key link between stem cell factors that fuel ovarian cancer's growth and patient prognosis. The study, which paves the way for developing novel targeted ovarian cancer therapies, is published online in the current issue of Cell Cycle.

9 Jan 2013

Spectrum Pharmaceuticals reveals positive RenaZorb Phase 1 clinical trial results

Spectrum Pharmaceuticals, a biotechnology company with fully integrated commercial and drug development operations with a primary focus in hematology and oncology, today announced positive, statistically significant data from the Company's Phase 1 clinical trial evaluating the safety and tolerability of RenaZorb (also referred to as SPI-014) in healthy volunteers.

8 Jan 2013

Multiple birth hip dysplasia screening questioned

Ultrasound screening for developmental dysplasia of the hip is unnecessary in twins and triplets without signs of the condition, say UK researchers.

7 Jan 2013

ParoChip can allow dentists to quickly detect and analyze periodontitis pathogens

Bleeding gums during tooth brushing or when biting into an apple could be an indication of periodontitis, an inflammatory disease of the tissues that surround and support the teeth. Bacterial plaque attacks the bone, meaning teeth can loosen over time and in the worst case even fall out, as they are left without a solid foundation to hold them in place.

4 Jan 2013

Markey practitioner receives Lexington Cancer Foundation grant to continue JSJ program

The University of Kentucky Markey Cancer Center's Jennifer Bradley has received funding from the Lexington Cancer Foundation to continue the Jin Shin Jyutsu program in 2013.

4 Jan 2013

FDA clears Soft Tissue Regeneration’s STR GRAFT

Soft Tissue Regeneration, an early stage orthopedic device company that has developed a breakthrough tissue engineering platform used to regenerate ligaments and tendons, announced today that it has received FDA clearance to market its STR GRAFT, a biodegradable scaffold used for soft tissue augmentation and rotator cuff repair.

3 Jan 2013

Novel implant for craniofacial reconstruction has mixed results

A single-stage, surface-mounted implant designed using the principles of the intraosseous transcutaneous amputation prosthesis is an effective bone anchor for an external prosthesis but may not produce good cosmetic outcomes in complex craniofacial reconstruction, researchers say.

3 Jan 2013

18F-FDG PET/CT may become important distant staging modality in patients with breast cancer

New research published in the January issue of The Journal of Nuclear Medicine shows that 18F-fludeoxyglucose (18F-FDG) positron emission tomography (PET)/computed tomography (CT) imaging offers significant prognostic stratification information at initial staging for patients with locally advanced breast cancer. When compared to conventional imaging, 18F-FDG PET/CT more accurately showed lesions in the chest, abdomen and bones in a single session, changing management for more than 50 percent of the patients in the study.

3 Jan 2013

Heart attack patients may benefit from mild to moderate sleep-disordered breathing

People who suffer from breathing disorders such as sleep apnea are usually at higher risk for cardiovascular disease. But an intriguing new study from Technion-Israel Institute of Technology scientists suggests that some heart attack patients with these conditions may actually benefit from mild to moderate sleep-disordered breathing.

3 Jan 2013

Soligenix's OrbeShield granted FDA oral BDP orphan drug designation

Soligenix, Inc., a development stage biopharmaceutical company, announced today that the Office of Orphan Products Development of the US Food and Drug Administration (FDA) has granted orphan drug designation to OrbeShield (oral beclomethasone 17,21-dipropionate or oral BDP) for the prevention of death following a potentially lethal dose of total body irradiation during or after a radiation disaster.

2 Jan 2013

Anesthesia choice may benefit knee arthroplasty patients

Spinal anesthesia could reduce the risk for postoperative complications in select patients undergoing total knee arthroplasty, US researchers say.

28 Dec 2012

Study suggests genetic component in pain response among children

At least two common gene variants are linked to "clinically meaningful" differences in pain scores in children after major surgery, reports a study in the January issue of Anesthesia & Analgesia, official journal of the International Anesthesia Research Society (IARS).

25 Dec 2012

Comorbidity could alter joint arthroplasty prognosis

The long-term outcome of hip and knee arthroplasty may be significantly influenced by comorbidity, suggest results from a large register-based study of over 96,000 osteoarthritis patients.

22 Dec 2012

Extended steroid treatment fails to reduce pediatric nephrotic relapse

Study findings indicate that extending initial prednisolone treatment durations in patients with pediatric nephrotic syndrome from 3 to 6 months without increasing the overall dose does not reduce the number of relapses.

22 Dec 2012

New Nationwide Children's exercise program for pediatric cancer survivors

There are many health effects that a patient may need to overcome after winning a battle against cancer. Cancer treatments can affect the patient's balance, agility, coordination, prompt weight gain and other physical ailments. At Nationwide Children's Hospital, beating cancer doesn't mark the end of a child's treatment regimen. A new exercise program at the hospital helps pediatric cancer survivors and those in remission regain both physical strength and confidence.

21 Dec 2012

Real estate businessman delivers $2.5M gift to University of Chicago Medicine for GI study

Real estate businessman Seymour "Sy" Taxman and his wife, Nancy, presented a gift of $2.5 million to the University of Chicago Medicine on Wednesday in honor of the late Joseph B. Kirsner, MD, PhD, the Louis Block Distinguished Service Professor of Medicine and a pioneer in the research and treatment of digestive disease.

21 Dec 2012

Study examines role of race and ethnicity in stem cell donation

New research examining the role of race and ethnicity in an individual's decision to become a donor for hematopoietic cell transplantation (HCT) identifies several factors associated with varied participation rates in national donor registries across racial/ethnic groups. Results of this first-of-its-kind study are published online today in Blood, the Journal of the American Society of Hematology (ASH).

21 Dec 2012

Bone News and Research

Clinical trials aim to repair bones using adult stem cells combined with biomaterials

Leptin hormone also regulates airway diameter

CTI initiates enrollment in pacritinib Phase 3 trial for myelofibrosis

Key link between stem cell factors that fuel ovarian cancer's growth and patient prognosis

Spectrum Pharmaceuticals reveals positive RenaZorb Phase 1 clinical trial results

Multiple birth hip dysplasia screening questioned

ParoChip can allow dentists to quickly detect and analyze periodontitis pathogens

Markey practitioner receives Lexington Cancer Foundation grant to continue JSJ program

FDA clears Soft Tissue Regeneration’s STR GRAFT

Novel implant for craniofacial reconstruction has mixed results

18F-FDG PET/CT may become important distant staging modality in patients with breast cancer

Heart attack patients may benefit from mild to moderate sleep-disordered breathing

Soligenix's OrbeShield granted FDA oral BDP orphan drug designation

Anesthesia choice may benefit knee arthroplasty patients

Study suggests genetic component in pain response among children

Comorbidity could alter joint arthroplasty prognosis

Extended steroid treatment fails to reduce pediatric nephrotic relapse

New Nationwide Children's exercise program for pediatric cancer survivors

Real estate businessman delivers $2.5M gift to University of Chicago Medicine for GI study

Study examines role of race and ethnicity in stem cell donation

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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