Genes News and Research

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Key protein in cholera-causing bacteria enables them to adapt to temperature changes

Scientists have discovered an essential protein in cholera-causing bacteria that allows them to adapt to changes in temperature, according to a study published today in eLife.

17 Feb 2021

Nsp1 protein could provide new treatments for COVID-19

A study that identifies how a coronavirus protein called Nsp1 blocks the activity of genes that promote viral replication provides hope for new COVID-19 treatments.

16 Feb 2021

Researchers discover the role of a gene involved in cardiac rhythm

Researchers have used the zebrafish (Danio rerio) to identify the role of a gene involved in cardiac rhythm, which could help explain the fundamentals of what it takes to make a human heartbeat.

16 Feb 2021

Genetic variant inherited from Neanderthals associated with protection against severe COVID-19

SARS-CoV-2, the virus that causes COVID-19, impacts people in different ways after infection. Some experience only mild or no symptoms at all while others become sick enough to require hospitalization and may develop respiratory failure and die.

16 Feb 2021

Mice study suggests novel approach to treat a type of common glioma

Gliomas are common brain tumors that comprise about one third of all cancers of the nervous system. In a study funded by the National Institutes of Health, researchers tested a novel combination treatment approach on mice with tumors with characteristics similar to human astrocytomas--a type of slow-growing glioma--and found tumor regression in 60 percent of the mice treated.

16 Feb 2021

Researchers identify key genetic changes in interstitial kidney tissue of people with diabetes

Researchers from Indiana University have identified key genetic changes in the interstitial kidney tissue of people with diabetes, a discovery that signifies the potential for a revolutionary new genetic approach to the treatment of kidney disease.

16 Feb 2021

Study outlines the reasons to test pediatric cancer patients for inherited genes

Because cancers in children are rare, many details about their biology remain unknown. In the field of cancer genetics, there's a limited understanding of how inherited genetic changes may contribute to the formation and growth of tumors.

16 Feb 2021

Study highlights the epigenetics of life at high altitudes

Humans inhabit an incredible range of environments across the globe, from arid deserts to frozen tundra, tropical rainforests, and some of the highest peaks on Earth.

16 Feb 2021

Maternal cardiovascular health in pregnancy associated with child's heart health in adolescence

A mother's heart health while she is pregnant may have a significant impact on her child's cardiovascular health in early adolescence (ages 10 to 14), according to a new study from Northwestern Medicine and the Ann & Robert H. Lurie Children's Hospital of Chicago.

16 Feb 2021

Scientists discover two unique subtypes of a prominent mutation in patients with AML

Using advanced RNA sequencing, scientists have identified two unique subtypes of a prominent mutation present in many patients with Acute Myeloid Leukemia (AML) – called NPM1 – that could help predict survival and improve treatment response for patients whose leukemic cells bear the mutation.

16 Feb 2021

Clonally expanded plasma cell lineages in SARS-CoV-2 produce specific neutralizing antibodies

A new preprint research paper posted to the bioRxiv server provides a greater understanding of the aspect of humoral immunity against the virus – the plasma cells that pour out a flood of specific antibodies targeting various epitopes on the pathogen.

16 Feb 2021

Research shows rapid global spread of Southern California COVID-19 strain

A new strain of the coronavirus in Southern California, first reported last month by Cedars-Sinai, is rapidly spreading across the country and around the world as travelers apparently carry the virus with them to a growing list of global destinations, according to new research published today in the peer-reviewed Journal of the American Medical Association.

15 Feb 2021

Scientists study how a single gene alteration may have separated modern humans from extinct hominins

As a professor of pediatrics and cellular and molecular medicine at University of California San Diego School of Medicine, Alysson R. Muotri, PhD, has long studied how the brain develops and what goes wrong in neurological disorders.

15 Feb 2021

Scientists discover new immunotherapy target for malignant brain tumors

Scientists say they have discovered a potential new target for immunotherapy of malignant brain tumors, which so far have resisted the ground-breaking cancer treatment based on harnessing the body's immune system.

15 Feb 2021

RIG-1-like receptors may play dominant role in suppressing SARS-CoV-2 infection

A new study by researchers at the University of Connecticut Health Center, USA, reports the crucial nature of the pathogen pattern recognition receptor (PRRs), especially the two RLRs, retinoic acid-inducible gene I (RIG-I) and melanoma differentiation-associated protein 5 (MDA5), in triggering host cell immune responses within the cell. The RLRs are viral RNA sensors.

15 Feb 2021

Genes News and Research

Key protein in cholera-causing bacteria enables them to adapt to temperature changes

Nsp1 protein could provide new treatments for COVID-19

Researchers discover the role of a gene involved in cardiac rhythm

Genetic variant inherited from Neanderthals associated with protection against severe COVID-19

Mice study suggests novel approach to treat a type of common glioma

Researchers identify key genetic changes in interstitial kidney tissue of people with diabetes

Study outlines the reasons to test pediatric cancer patients for inherited genes

Study highlights the epigenetics of life at high altitudes

Maternal cardiovascular health in pregnancy associated with child's heart health in adolescence

Scientists discover two unique subtypes of a prominent mutation in patients with AML

Clonally expanded plasma cell lineages in SARS-CoV-2 produce specific neutralizing antibodies

Research shows rapid global spread of Southern California COVID-19 strain

Scientists study how a single gene alteration may have separated modern humans from extinct hominins

Scientists discover new immunotherapy target for malignant brain tumors

RIG-1-like receptors may play dominant role in suppressing SARS-CoV-2 infection

LifeArc supports the GenOMICC COVID-19 Study

Study finds certain plasma microRNAs as diagnostic biomarkers for mild traumatic brain injury

Researchers study host and viral transcriptomes in tandem to shed light on SARS-CoV-2 infection

A machine learning approach to identify drugs that could be repurposed to fight COVID-19

Male fruit flies win genetic race with rivals in post-mating fertilization game

eBook: Using iPSCs models for human disease research and drug discovery eBook

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Industry Focus eBook - Cell biology (5th edition)

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Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics