Stem Cells News and Research

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Stem cells have the remarkable potential to develop into many different cell types in the body during early life and growth. In addition, in many tissues they serve as a sort of internal repair system, dividing essentially without limit to replenish other cells as long as the person or animal is still alive. When a stem cell divides, each new cell has the potential either to remain a stem cell or become another type of cell with a more specialized function, such as a muscle cell, a red blood cell, or a brain cell.

New strategies for successful donor adult stem cell transplants in blood cancer patients

Findings by UT Southwestern Medical Center researchers may suggest new strategies for successful donor adult stem cell transplants in patients with blood cancers such as leukemia, lymphoma and myeloma.

5 Aug 2011

Human brain cells created from skin cells: Potential for Alzheimer’s

This feat comes a year after researchers at Stanford University performed the same feat in mice, turning cells from the rodents' skin into neurons. The lab-created brain cells act the same as normal human brain cells, the researchers found. These cells have the same ability to send electric signals; they seem to express the same genes in the same ways; and they are able to communicate with other brain cells, as demonstrated in a lab dish and when implanted into mice.

5 Aug 2011

Stem cells could provide sperm for infertile males

Researchers have been successful in creating sperm-producing germ cells from stem cells in a lab and transferred them into infertile mice, which after the treatment were able to produce healthy offspring. This new development could help thousands of infertile men become fathers if the method proves similarly effective in humans.

5 Aug 2011

Key protein discoveries could lead to new lung repair therapies for children, adults

A team at The Saban Research Institute of Children's Hospital Los Angeles has made crucial discoveries about the role of key proteins in wound healing in the tiny air sacs in the lungs known as "alveoli" that could lead to new therapies for children and adults.

5 Aug 2011

Scientists convert human skin cells into forebrain neurons

Columbia University Medical Center researchers have for the first time directly converted human skin cells into functional forebrain neurons, without the need for stem cells of any kind.

5 Aug 2011

BD Biosciences, Fluidigm to co-host public seminars on isolation and analysis of single cells

Fluidigm Corporation announced today a collaboration with BD Biosciences, a segment of BD, to co-host a public seminar series on the isolation and analysis of single cells. Entitled A Powerful Technique for Single-Cell Analysis, the public seminar series will showcase cell isolation using the BD FACSAria III Cell Sorter and analysis using the Fluidigm BioMark HD System.

From BD (Becton, Dickinson and Company) 5 Aug 2011

Roadmap to overcome obstacles for using induced pluripotent stem cells

The possibility of developing stem cells from a patient's own skin and using them to treat conditions as diverse as Parkinson's disease, Alzheimer's disease and cancer has generated tremendous excitement in the stem cell research community in recent years. Such therapies would avoid the controversial need for using stem cells derived from human embryos, and in theory, also bypass immunological problems inherent in using cells from one person to treat another.

5 Aug 2011

RNAi screen identifies Brd4 as a therapeutic target for acute myeloid leukemia

Scientists at Cold Spring Harbor Laboratory (CSHL) and five other institutions have used an unconventional approach to cancer drug discovery to identify a new potential treatment for acute myeloid leukemia.

4 Aug 2011

Hopkins stem cell research to examine how gene variants cause blood clotting disorders

4 Aug 2011

Celldex second quarter net loss increases to $10.2 million

Celldex Therapeutics, Inc. today reported financial results for the second quarter ended June 30, 2011. Celldex reported a net loss of $10.2 million, or $0.27 per share, for the second quarter of 2011 compared to a net loss of $9.5 million, or $0.30 per share, for the second quarter of 2010.

3 Aug 2011

GSK, NPS enter agreement to evaluate ronacaleret in new indications

NPS Pharmaceuticals, Inc., a specialty pharmaceutical company developing orphan therapeutics for rare gastrointestinal and endocrine disorders, today reported that it has entered into a new agreement with GlaxoSmithKline (GSK), that terminates and replaces a prior collaborative research and license agreement between NPS and GSK from 1993, which focused on the discovery and development of small molecule antagonists of the calcium receptor that increase secretion of parathyroid hormone.

3 Aug 2011

Scientists look to create blood platelets from stem cells to study genetics of blood clotting disorders

Johns Hopkins scientists have launched a pioneering research program to create, for the first time, human platelet cells from stem cells in order to study inherited blood clotting abnormalities ranging from clots that cause heart attacks and stroke to bleeding disorders. The study is funded by a $9 million grant from the National Institutes of Health (NIH) as part of a nationwide initiative to examine how genetic variations cause heart, lung and blood diseases.

2 Aug 2011

Blocking IGF-1 receptor cripples cancer growth in T cell acute lymphoblastic leukemia

Blocking a growth factor receptor cripples cancer growth in a form of T cell leukemia, according to a study published online on August 1 in the Journal of Experimental Medicine.

2 Aug 2011

Taxoxifen combined with dasatinib reverses chemo-resistance in breast cancer cells

Taking a leukemia chemotherapy drug may help breast cancer patients who don't respond to tamoxifen overcome resistance to the widely-used drug, new research from the Kimmel Cancer Center at Jefferson suggests.

2 Aug 2011

Researchers reveal molecular mechanisms responsible for organizing intestinal epithelium

How do cells know where to position themselves and where to accumulate in order to carry out their functions correctly within each organ? Researchers with the Colorectal Cancer Lab at IRB Barcelona have revealed the molecular mechanisms responsible for organizing the intestinal epithelium into distinct comportments, defined by frontiers or territories.

1 Aug 2011

UT Southwestern's support group book shares stories of members whose wives battled cancer

When a loved one has cancer, it affects the entire family. For men, many of whom are less likely to take advantage of a support group, this can leave a void with devastating emotional consequences.

30 Jul 2011

RegenoCELL to open new facility in Panama for treatment of congestive heart failure

RegenoCELL Therapeutics, Inc., a leader in adult stem cell therapy, is pleased to announce it is planning to open another state of the art facility in Panama for patients to be treated for congestive heart failure and peripheral artery disease with its autologous stem cell therapy.

30 Jul 2011

Federal judge upholds Obama rule on stem cell research

A U.S. judge Wednesday upheld the government rules that allow federal funding of human embryonic stem cell research that might lead to cures for deadly diseases affecting millions of Americans.

29 Jul 2011

Scientist discovers novel way to convert human skin cells into neurons

A scientist at the Gladstone Institutes has discovered a novel way to convert human skin cells into brain cells, advancing medicine and human health by offering new hope for regenerative medicine and personalized drug discovery and development.

29 Jul 2011

Sigma-Tau, Soligenix expand partnership to develop and commercialize orBec in Europe

Soligenix, Inc., a late-stage biopharmaceutical company, announces the expansion and amendment of its North American licensing partnership with Sigma-Tau Pharmaceuticals, Inc. for the development and commercialization of orBec into the European territory.

29 Jul 2011

Stem Cells News and Research

Further Reading

New strategies for successful donor adult stem cell transplants in blood cancer patients

Human brain cells created from skin cells: Potential for Alzheimer’s

Stem cells could provide sperm for infertile males

Key protein discoveries could lead to new lung repair therapies for children, adults

Scientists convert human skin cells into forebrain neurons

BD Biosciences, Fluidigm to co-host public seminars on isolation and analysis of single cells

Roadmap to overcome obstacles for using induced pluripotent stem cells

RNAi screen identifies Brd4 as a therapeutic target for acute myeloid leukemia

Hopkins stem cell research to examine how gene variants cause blood clotting disorders

Celldex second quarter net loss increases to $10.2 million

GSK, NPS enter agreement to evaluate ronacaleret in new indications

Scientists look to create blood platelets from stem cells to study genetics of blood clotting disorders

Blocking IGF-1 receptor cripples cancer growth in T cell acute lymphoblastic leukemia

Taxoxifen combined with dasatinib reverses chemo-resistance in breast cancer cells

Researchers reveal molecular mechanisms responsible for organizing intestinal epithelium

UT Southwestern's support group book shares stories of members whose wives battled cancer

RegenoCELL to open new facility in Panama for treatment of congestive heart failure

Federal judge upholds Obama rule on stem cell research

Scientist discovers novel way to convert human skin cells into neurons

Sigma-Tau, Soligenix expand partnership to develop and commercialize orBec in Europe

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