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Global Alliance for Pharmacogenomics

Leaders at the National Institutes of Health and the Center for Genomic Medicine in Japan have signed a letter of intent creating a Global Alliance for Pharmacogenomics.

15 Apr 2008

No guarantee that bottled water is any better than tap water

How much do you spend on bottled water? If you buy certain brands thinking the water is cleaner or safer, experts say you may as well be pouring money down the drain.

15 Apr 2008

Loop diuretics linked to bone loss in older men

Older men who take loop diuretics, commonly prescribed drugs for heart failure and hypertension, appear to have increased rates of hip bone loss than men who are not taking this medication, according to a report in the April 14 issue of Archives of Internal Medicine, one of the JAMA/Archives journals.

15 Apr 2008

Profoundly important discovery of differences in heart's precursor cells

Scientists have long thought that the cells that ultimately give rise to the heart all respond to the same cue before turning into the muscle tissue of this vital organ.

15 Apr 2008

DASH diet also may cut risk for heart disease, stroke

Women who eat diets similar to the Dietary Approaches to Stop Hypertension (DASH) diet -which is low in animal protein, moderate in low-fat dairy products and high in plant proteins, fruits and vegetables - appear to have a lower risk of coronary heart disease and stroke, according to a report in the April 14 issue of Archives of Internal Medicine, one of the JAMA/Archives journals.

15 Apr 2008

Women's colon cancer risk perception associated with screening behavior

Women's perception of their cancer risk appears to vary by race and may affect how likely they are to undergo screenings, particularly for colon cancer, according to a report in the April 14 issue of Archives of Internal Medicine.

15 Apr 2008

Lipitor and Celebrex combined may halt prostate cancer

Researchers at Rutgers' Ernest Mario School of Pharmacy have shown that administering a combination of the widely used drugs Celebrex (celecoxib, a nonsteroidal anti-inflammatory drug) and Lipitor (atorvastatin, a cholesterol lowering drug) stops the transition of early prostate cancer to its more aggressive and potentially fatal stage.

15 Apr 2008

Best use for popular CAD assessment procedure is misunderstood

What is the best way to determine if you are developing the nation's most deadly condition, coronary artery disease (CAD)?

15 Apr 2008

Statins may help control blood pressure

Researchers in the States say that statins, the popular cholesterol-lowering drugs, may also lower blood pressure.

15 Apr 2008

Low birth weight linked to heart disease

According to new research from Britain, being small at birth along with an excessive weight gain during adolescence and young adulthood are indicators for future heart disease risk.

14 Apr 2008

New hope for blood disorder anaemia

A new understanding of how red blood cell production is controlled could lead to improvements in the treatment of the blood disorder anaemia, according to West Australian medical researchers.

13 Apr 2008

Stopping unwanted cell death: novel avenue for drug development

Research published in Nature Chemical Biology reveals that three specific inhibitors of a cell death pathway, termed necroptosis, all target and inhibit RIP1 kinase, a protein that can direct cells into necrosis.

13 Apr 2008

Stem cells and their role in malignant brain tumours

Speaking at the UK National Stem Cell Network Annual Science Meeting in Edinburgh, Professor Silvia Marino shows how the mechanisms normally involved in balancing different functions of stem cells may also contribute to cancer.

13 Apr 2008

Researchers study Rituximab's action on cancer stem cells

Preliminary data from one of the first clinical trials to test a stem cell-targeting drug in cancer patients shows that while the drug did not prolong survival, its suppressing effect on patients' stem cells was impressive enough to send investigators looking for a better drug to try.

13 Apr 2008

Targeted therapy combo overcomes treatment resistance in liver cancer

Researchers at the University of Pennsylvania School of Medicine and Abramson Cancer Center reported at the annual meeting of the American Association for Cancer Research that combining two targeted therapies overcomes treatment resistance in liver cancer cell lines.

13 Apr 2008

Radiation beneficial for older breast cancer patients

A breast cancer patient's age alone should not determine whether or not she receives standard breast-conservation treatments, including a lumpectomy and radiation therapy; however, if additional health problems (comorbidities) are present, treatments should be individualized based on age and the type of comorbidities, according to a study in the April 1 edition of the International Journal for Radiation Oncology-Biology-Physics, the official journal of the American Society for Therapeutic Radiology and Oncology.

13 Apr 2008

Depression in seniors

Even after the age of 70, people prone to feelings of anxiety, worry, distress and insecurity face a risk for a first lifetime episode of clinically significant depression, according to a unique study led by a University of Rochester Medical Center researcher.

13 Apr 2008

Targeted therapies overcome treatment resistance in liver cancer cell lines

Researchers at the University of Pennsylvania School of Medicine and Abramson Cancer Center reported today at the annual meeting of the American Association for Cancer Research that combining two targeted therapies overcomes treatment resistance in liver cancer cell lines.

13 Apr 2008

Discovery of link between protein, prognosis in breast cancer

Oregon Health & Science University Cancer Institute researchers have found that a tumor protein present in an aggressive form of breast cancer is related to a poor prognosis.

13 Apr 2008

Medicare reimbursement changes likely influenced changes in prostate cancer treatment

Financial pressures from Medicare reimbursement changes may have caused physicians to switch from providing hormonal-induced castration to providing surgical castration for men with prostate cancer.

13 Apr 2008