Angiotensin Converting Enzyme 2 News and Research

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How have human organoids been used in research to study SARS-CoV-2?

In a recent review published in the journal Organoids, scientists have presented an overview on the use of human stem cell-derived organoids in understanding functionality and cellular tropism of severe acute respiratory syndrome coronavirus 2 (SARS-Cov-2), a deadly beta-coronavirus responsible for the ongoing coronavirus disease 2019 (COVID-19) pandemic.

7 Mar 2022

Impact of humoral responses in COVID-19

New research discussed the function and impact of humoral immune responses in COVID-19.

7 Mar 2022

How does COVID-19 affect patients with idiopathic pulmonary fibrosis?

A new study discusses the outcomes of idiopathic pulmonary fibrosis patients with confirmed SARS-CoV-2 infection.

6 Mar 2022

Combating COVID cytokine storm with targeted nucleic acid therapies

Researchers examine current nucleic acid-based treatments against COVID-19 and their methods of action.

6 Mar 2022

Disruption of sleep and circadian rhythm can increase the chances of contracting a virus

A recent study explores the effect of sleep and circadian rhythm dispersion on mouse lung transcriptome after six of hours sleep deprivation.

6 Mar 2022

Aldosterone levels undetectably low in hospitalized COVID-19 patients

A new study reports finds very low aldosterone levels in a subset of COVID-19 patients.

6 Mar 2022

Angiotensin-converting enzyme 2-based mutant decoy effectively reduces COVID-19 in mice

Researchers engineered a mutant ACE2 decoy that effectively protected human lung epithelia from SARS-CoV-2 infection by competitively binding to its spike protein.

3 Mar 2022

8G3 broad-spectrum antibody effective against all SARS-CoV-2 variants, including Omicron

Researchers assess the efficacy of 8G3, a B-cell neutralizing antibody against SARS-CoV-2 variants, including the most recent Omicron variant.

3 Mar 2022

Exploring Oxford nanopore technology-based on-site SARS-CoV-2 genome sequencing

In a new study, researchers performed genomic sequencing of SARS-CoV-2-infected samples and aimed to identify the dominant variant, assess the mutation profile, and determine the sample-to-sequence turnover time.

1 Mar 2022

Analyzing transcriptomic landscape of SARS-CoV-2-infected lung cells

In a new study, researchers used deep transcriptome analysis to examine the coding and non-coding transcriptional landscape of lung cells infected with SARS-CoV-2.

1 Mar 2022

Epistatic shifts rationalize mutational constraints of SARS-CoV-2 receptor-binding domain

Researchers used deep mutational scans to measure the effect of each amino-acid mutation in the receptor-binding domain of SARS-CoV-2 Wuhan-Hu-1, Alpha, Beta, Delta, and Eta variants.

1 Mar 2022

SARS-CoV-2 protein interactions with viral and host RNAs in authentic virus-infected cells

Researchers investigated protein interactions of SARS-CoV-2 with host and viral RNAs in infected cells.

1 Mar 2022

Recombinant adenovirus vector vaccine generates mucosal antibodies against SARS-CoV-2

In a recent study posted to the bioRxiv* server, researchers assessed the immunogenicity of the self-developed recombinant adenovirus vector (rAd5) vaccine on macaques. They evaluated the efficacy of three candidate vaccines, ED88, ED90, and ED94, to select the most appropriate one for future development.

1 Mar 2022

Angiotensin Converting Enzyme 2 News and Research

How have human organoids been used in research to study SARS-CoV-2?

Impact of humoral responses in COVID-19

How does COVID-19 affect patients with idiopathic pulmonary fibrosis?

Combating COVID cytokine storm with targeted nucleic acid therapies

Disruption of sleep and circadian rhythm can increase the chances of contracting a virus

Aldosterone levels undetectably low in hospitalized COVID-19 patients

Angiotensin-converting enzyme 2-based mutant decoy effectively reduces COVID-19 in mice

8G3 broad-spectrum antibody effective against all SARS-CoV-2 variants, including Omicron

Exploring Oxford nanopore technology-based on-site SARS-CoV-2 genome sequencing

Analyzing transcriptomic landscape of SARS-CoV-2-infected lung cells

Epistatic shifts rationalize mutational constraints of SARS-CoV-2 receptor-binding domain

SARS-CoV-2 protein interactions with viral and host RNAs in authentic virus-infected cells

Recombinant adenovirus vector vaccine generates mucosal antibodies against SARS-CoV-2

Biophysical fitness profile of SARS-CoV-2 Delta variant

COVID-19 severity is correlated with body composition

Histopathologic and molecular effects in the placenta after SARS-CoV-2 infection during pregnancy

Molecular insights on the possible connection of SARS-CoV-2 and nicotinic acetylcholine receptors

Study finds lower prevalence of post-acute SARS-CoV-2 symptomology in vaccinated individuals

Triple antibody cocktail is a promising candidate for immunotherapy against SARS-CoV-2 variants of concern

Will Omicron BA.2 become the next dominant variant?

Industry Focus eBook - Analytical Chemistry (2nd Edition) eBook

How Omics Technologies Are Transforming Biological Research and Drug Discovery

How microplastics and bacteria interact to drive antibiotic resistance

Single-cell proteomics: Revealing proteome diversity from cellular heterogeneity to non-canonical biology

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