Bone Marrow News and Research

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Bone Marrow is the soft, sponge-like tissue in the center of most bones. It produces white blood cells, red blood cells, and platelets.

Researchers discover new mechanisms for bone loss in gum disease

Tokyo University of Agriculture and Technology researchers reported on a new discovery regarding the mechanisms for bone loss in gum disease (periodontitis). They found that double stranded RNA molecules can activate the immune system response that leads to deterioration of bone.

8 Apr 2022

Curcumin released from magnetic hydrogels promotes the secretion of vascular endothelial growth factor

A finding by UC Riverside bioengineers could hasten development of lab-grown blood vessels and other tissues to replace and regenerate damaged tissues in human patients. The results are published in ACS Applied Materials and Interfaces.

6 Apr 2022

Researchers develop novel device to “cleanse” the blood of chemotherapeutic drugs

For patients with cancer, the tumor-killing power of chemotherapeutic drugs is a double-edged sword. While many cancer drugs kill tumor cells, they can also harm healthy cells as they travel throughout the bloodstream.

6 Apr 2022

SEACells: an algorithm for identifying metacells

A new study has presented single-cell aggregation of cell-states (SEACells), a graph-based algorithm for identifying metacells.

6 Apr 2022

Study shows that the SARS-CoV-2 envelope protein potently restricts HIV-1 infection

Researchers demonstrated that E proteins of β-coronaviruses could restrict HIV-1 infection.

30 Mar 2022

10-second videos of white blood cell motion improve the prediction of blood cancer relapse

In a new study from Vanderbilt University Medical Center, 10-second videos of white blood cell motion in the skin's microvasculature greatly improved the prediction of which stem cell and bone marrow transplant patients would have a relapse of their blood cancer.

29 Mar 2022

Study investigates room-temperature stable, self-amplifying RNA vaccine against SARS-CoV-2

Researchers applied a previously developed thermostable self-amplifying ribonucleic acid vaccine to COVID-19.

28 Mar 2022

Biologists discover gene deletion behind abnormality in blood cancer cells

The mystery is being unraveled of why the control centers, or nuclei, of certain blood cancer cells have a distinctly odd shape.

27 Mar 2022

Spinal fluid sampling could provide data about tumors sooner than MRIs

Treatment for glioma has long relied on MRI imaging to track tumor markers and treatment response.

24 Mar 2022

Using CRISPR/Cas to develop biosafety materials

Researchers discuss the use of the highly efficient CRISPR/Cas technologies to identify viral genome sequences for biosafety purposes.

21 Mar 2022

20% of childhood AML cases associated with rare genetic changes inherited through family bloodlines

It's a diagnosis you never want to hear: Acute Myeloid Leukemia (AML). These three words represent a devastating diagnosis of childhood cancer with dire consequences for many families.

21 Mar 2022

Could sound waves help to regrow bones?

In this interview, we speak to Dr. Amy Gelmi and Professor Leslie Yeo about their new research that looked at using sound waves to regrow bones.

21 Mar 2022

New discovery points to potential drug targets for ASXL1-mutant chronic myelomonocytic leukemia

New research from Mayo Clinic's Center for Individualized Medicine finds that patients with ASXL1-mutant chronic myelomonocytic leukemia - an uncommon type of cancer of the bone marrow - have distinctive epigenetic changes that can activate harmful genes and cause the cancer to grow faster.

18 Mar 2022

Discovery may open novel avenues to prevent or treat hematological malignancies

Scientists at Yale Cancer Center have discovered new consequences of specific gene mutations that play a role in the development of myelodysplastic syndromes (MDS) and acute myeloid leukemia (AML).

17 Mar 2022

Cell fusion could be a potential therapeutic strategy to treat retinal damage

Fusing human retinal cells with adult stem cells could be a potential therapeutic strategy to treat retinal damage and visual impairment, according to the findings of a new study published in the journal eBioMedicine.

15 Mar 2022

Study raises hopes for effective treatment of infant B acute lymphoblastic leukemia

New research has begun to unravel the mystery of why a particular form of leukemia in infants has defied efforts to improve outcomes, despite significant improvements in treating older children.

14 Mar 2022

New Phase 1 clinical trial of mRNA HIV vaccine enrolls first participant

The first 12 study participants have been enrolled in a new Phase 1 clinical trial using the messenger ribonucleic acid (mRNA) vaccine technology developed by Moderna.

14 Mar 2022

IPD pooled analysis quantifies the underlying hematological response following malaria infection

A new malaria study using a very large analysis of pooled individual patient data (IPD) from more than 70,000 patients of all ages, has been published today in BMC Medicine.

9 Mar 2022

Study explores immune escape mutations caused by prolonged viral shedding in immunocompromised COVID-19 patient

A new study examined a unique case of extended viral shedding in an immunocompromised patient that produced a series of SARS-CoV-2 immune escape mutations over a seven-month period.

8 Mar 2022

Study provides insight into what causes therapy failure in patients with myelodysplastic syndromes

Researchers from The University of Texas MD Anderson Cancer Center discovered that treatment resistance in patients with myelodysplastic syndromes (MDS) is caused by two distinct classes of stem cells and identified possible therapeutic approaches that target these cells.

3 Mar 2022

Bone Marrow News and Research

Further Reading

Researchers discover new mechanisms for bone loss in gum disease

Curcumin released from magnetic hydrogels promotes the secretion of vascular endothelial growth factor

Researchers develop novel device to “cleanse” the blood of chemotherapeutic drugs

SEACells: an algorithm for identifying metacells

Study shows that the SARS-CoV-2 envelope protein potently restricts HIV-1 infection

10-second videos of white blood cell motion improve the prediction of blood cancer relapse

Study investigates room-temperature stable, self-amplifying RNA vaccine against SARS-CoV-2

Biologists discover gene deletion behind abnormality in blood cancer cells

Spinal fluid sampling could provide data about tumors sooner than MRIs

Using CRISPR/Cas to develop biosafety materials

20% of childhood AML cases associated with rare genetic changes inherited through family bloodlines

Could sound waves help to regrow bones?

New discovery points to potential drug targets for ASXL1-mutant chronic myelomonocytic leukemia

Discovery may open novel avenues to prevent or treat hematological malignancies

Cell fusion could be a potential therapeutic strategy to treat retinal damage

Study raises hopes for effective treatment of infant B acute lymphoblastic leukemia

New Phase 1 clinical trial of mRNA HIV vaccine enrolls first participant

IPD pooled analysis quantifies the underlying hematological response following malaria infection

Study explores immune escape mutations caused by prolonged viral shedding in immunocompromised COVID-19 patient

Study provides insight into what causes therapy failure in patients with myelodysplastic syndromes

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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