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Researchers find how different neurons work together to reduce responses to frequent sounds

Being able to understand speech is essential to our evolution as humans. Hearing lets us perceive the same word even when spoken at different speeds or pitches, and also gives us extra sensitivity to unexpected sounds. Now, new studies from the Perelman School of Medicine at the University of Pennsylvania clarify how these two crucial features of audition are managed by the brain.

12 Oct 2015

AGS releases updated, expanded Beers Criteria to improve medication use in older adults

The American Geriatrics Society today released its second updated and expanded Beers Criteria--lists of potentially inappropriate medications for older adults who are not receiving hospice or palliative care, and one of the most frequently cited reference tools in the field of geriatrics.

12 Oct 2015

Immune-molecule-based mop-up therapy reduces specific type of breast tumor in mice

Disabling a cancer-causing pathway and administering an immune-molecule-based mop-up therapy eradicated a specific type of breast tumor in mice, according to researchers in the Perelman School of Medicine at the University of Pennsylvania.

8 Oct 2015

Penn Medicine announces $375,000 in new grants to support BRCA-focused research projects

Penn Medicine's Basser Center for BRCA announced $375,000 in new grant funding to support BRCA-focused research projects across the nation. The grants are aimed at advancing the care of patients living with BRCA1 and BRCA2 mutations.

7 Oct 2015

New guidance statement on palliative care to be presented at 2015 Palliative Care in Oncology Symposium

A new guidance statement from the American Society of Clinical Oncology and the American Academy of Hospice and Palliative Medicine is being presented for the first time at the 2015 Palliative Care in Oncology Symposium in Boston.

7 Oct 2015

Study describes new genome screen that identifies partner molecules of cell-waste disposal proteins

Rhythmic expression of key genes is essential for maintaining proper timekeeping of the body's clock. In addition, rhythmic degradation of clockwork proteins is also crucial. However, surprisingly, researchers know little about these specific processes.

7 Oct 2015

New countries join ESMO Designated Centre of Integrated Oncology and Palliative Care

Patient eligibility for opioids is seriously restricted in some countries, with the highest rate of limited access to palliative care found in the Middle East, followed by Latin America and the Caribbean and Asia. Data are revealed by the ESMO Global Opioid Policy Initiative (GOPI) which identifies barriers to the availability and accessibility of essential pain relieving medication worldwide.

26 Sep 2015

Scripps becomes first health care provider in San Diego County to implant Evera MRI SureScan ICD System

Scripps Health is the first health care provider in San Diego County to use the only implantable cardioverter defibrillator (ICD) device approved for use with magnetic resonance imaging (MRI) scans.

26 Sep 2015

Cancer-causing gene disrupts internal rhythm, metabolic pathways in cancer cells

Myc is a cancer-causing gene responsible for disrupting the normal 24-hour internal rhythm and metabolic pathways in cancer cells, found a team led by researchers from the Perelman School of Medicine at the University of Pennsylvania. Postdoctoral fellow Brian Altman, PhD, and doctoral student Annie Hsieh, MD, both from the lab of senior author Chi Van Dang, MD, PhD, director Abramson Cancer Center, study body clock proteins associated with cancer cells.

18 Sep 2015

New Penn Medicine research shows vital role of Esrp1 and Esrp2 genes in skin, organ development

Knocking out one or both crucial regulatory genes caused cleft lip, skin barrier defects, and a host of other developmental problems in mice, according to new research from the Perelman School of Medicine at the University of Pennsylvania, hinting that abnormalities in these molecular pathways could underlie many birth defects that are presently not well understood. The two closely related regulatory genes are active in the normal development of mammals and govern how RNAs produced from the genes are joined to make final versions of the encoded protein, a process called alternative splicing.

16 Sep 2015

Location-dependent pattern in cilia length in mouse nasal cavity affects sensitivity to odors

Like the hairs they resemble, cilia come in all lengths, from short to long. But unlike the hair on our heads, the length of sensory cilia on nerve cells in our noses is of far more than merely cosmetic significance. A team of researchers from the Perelman School of Medicine at the University of Pennsylvania found a location-dependent pattern in cilia length in the mouse nasal cavity that affects sensitivity to odors.

14 Sep 2015

HealthSouth to offer $300M aggregate principal amount of senior notes through private placement

HealthSouth Corporation today announced it intends to offer through a private placement, subject to market and other conditions, $300 million aggregate principal amount of senior notes due 2025.

11 Sep 2015

Penn Medicine researchers show that DNA editing errors can lead to cancer

Sometimes when the immune system makes small mistakes, the body amplifies its response in a big way: Editing errors in the DNA of developing T and B cells can cause blood cancers. Now, researchers from the Perelman School of Medicine, University of Pennsylvania have shown that when the enzyme key to cutting and pasting segments of DNA hits so-called "off-target" spots on a chromosome, the development of immune cells can lead to cancer in animal models.

11 Sep 2015

Johns Hopkins researchers develop new resource tool to monitor trends in geriatric health services

Using data from their detailed analysis of senior medical services offered by nearly 5,000 U.S. hospitals before the 2009 passage of the Affordable Care Act (ACA), researchers led by a Johns Hopkins geriatrician say they have developed a Senior Care Services Scale (SCSS) that suggests a serious “mismatch” between what’s offered and what older adult populations need.

11 Sep 2015

New trial results show efficacy of novel enzyme-replacement therapy for genetic lipid disorder

Of the more than 50 known lysosomal storage diseases (LSDs)-rare inherited metabolic disorders-only seven can be treated with approved enzyme-replacement therapies.

10 Sep 2015

Offering women money to undergo mammograms ethically troubling, says Penn Medicine ethicist

The widespread practice of incentivizing mammogram completion via cash payments, typically by insurance companies and ranging from $10 to $250, is unethical according to a Viewpoint article published this week in JAMA by an expert from the Perelman School of Medicine at the University of Pennsylvania.

10 Sep 2015

Penns' Abramson Cancer Center rated as 'exceptional' by NCI

The University of Pennsylvania's Abramson Cancer Center (ACC) has received an "exceptional" rating by the National Cancer Institute during an extensive peer-review process for its five-year competitive research support grant. The rating is the highest possible for an NCI cancer center.

9 Sep 2015

Free online end of life care course

Sheffield Hallam University is teaming up with St Luke's Hospice to launch a free online course supporting health and social care workers in providing palliative or end of life care.

8 Sep 2015

Acupuncture may be viable treatment for women experiencing hot flashes

Acupuncture may be a viable treatment for women experiencing hot flashes as a result of estrogen-targeting therapies to treat breast cancer, according to a new study from researchers at the Perelman School of Medicine at the University of Pennsylvania. Hot flashes are particularly severe and frequent in breast cancer survivors, but current FDA-approved remedies for these unpleasant episodes, such as hormone replacement therapies are off-limits to breast cancer survivors because they include estrogen.

4 Sep 2015

Acupuncture: A viable treatment for breast cancer survivors experiencing hot flashes

3 Sep 2015

Hospice News and Research

Researchers find how different neurons work together to reduce responses to frequent sounds

AGS releases updated, expanded Beers Criteria to improve medication use in older adults

Immune-molecule-based mop-up therapy reduces specific type of breast tumor in mice

Penn Medicine announces $375,000 in new grants to support BRCA-focused research projects

New guidance statement on palliative care to be presented at 2015 Palliative Care in Oncology Symposium

Study describes new genome screen that identifies partner molecules of cell-waste disposal proteins

New countries join ESMO Designated Centre of Integrated Oncology and Palliative Care

Scripps becomes first health care provider in San Diego County to implant Evera MRI SureScan ICD System

Cancer-causing gene disrupts internal rhythm, metabolic pathways in cancer cells

New Penn Medicine research shows vital role of Esrp1 and Esrp2 genes in skin, organ development

Location-dependent pattern in cilia length in mouse nasal cavity affects sensitivity to odors

HealthSouth to offer $300M aggregate principal amount of senior notes through private placement

Penn Medicine researchers show that DNA editing errors can lead to cancer

Johns Hopkins researchers develop new resource tool to monitor trends in geriatric health services

New trial results show efficacy of novel enzyme-replacement therapy for genetic lipid disorder

Offering women money to undergo mammograms ethically troubling, says Penn Medicine ethicist

Penns' Abramson Cancer Center rated as 'exceptional' by NCI

Free online end of life care course

Acupuncture may be viable treatment for women experiencing hot flashes

Acupuncture: A viable treatment for breast cancer survivors experiencing hot flashes

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