Spike Protein News and Research

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Molecular dynamic simulations unveil conformational dynamics of SARS-CoV-2 spike protein RBD and ACE2 receptor

Researchers presented a systematic analysis of the affinity and conformational dynamics between the binding of SARS-CoV-2 receptor-binding domain spike protein and the host angiotensin-converting enzyme 2 receptor.

22 Mar 2022

Posaconazole found to be effective as a small molecule fusion inhibitor against SARS-CoV-2 variants

Researchers evaluated the importance of the Ex3Lx6L motif in SARS-CoV-2 entry into host cells mediated by the spike protein syncytium formation and membrane fusion.

22 Mar 2022

New research proves benefit of vaccination after recovery from COVID-19

When our immune system comes into contact with the SARS-CoV-2 coronavirus, it fights back and produces antibodies.

22 Mar 2022

Is COVID-19 on the verge of ending?

Researchers explore the changes arising in SARS-CoV-2 over time.

21 Mar 2022

A circRNA COVID vaccine with potential to neutralize SARS-CoV-2 variants

Researchers demonstrate the broad neutralization potential of a strategically engineered circRNA using mice as a model system.

21 Mar 2022

Mount Sinai launches phase 1 study to evaluate the safety, immunogenicity of egg-based COVID-19 vaccine

A team of clinical investigators at the Icahn School of Medicine at Mount Sinai has announced the launch of a Phase 1, open-label, placebo-controlled study to evaluate the safety and immunogenicity of an egg-based COVID-19 vaccine in healthy, vaccinated adults who have never been infected with COVID-19.

21 Mar 2022

Multiple inter-variant recombination events identified in Omicron subvariants

Newly emerging and circulating Omicron subvariants have originated partially through recombination with other variants.

20 Mar 2022

Response to COVID-19 boosters in seronegative multiple sclerosis patients

Researchers report humoral T-cell responses in seronegative MS patients after receiving a third COVID-19 booster vaccine dose.

20 Mar 2022

Omicron BA.1.1 and BA.2 subvariants with new mutations in New Zealand and Hong Kong

A new study describes mutations found in the SARS-CoV-2 BA.1 variant in Hong Kong and New Zealand.

20 Mar 2022

Acidity of expiratory aerosols influences infectivity of SARS-CoV-2

Researchers provide insight on the potentially significant impact of aerosol pH on the transmission of SARS-CoV-2.

20 Mar 2022

Texas Biomed and UAB partnership uncovers a new, potent antibody cocktail against all coronaviruses

As SARS-CoV-2 has continued to evolve and outsmart existing treatments, scientists have not let up looking for ever-more effective tools to keep people safe and successfully recover from COVID-19, and to prepare for future outbreaks.

18 Mar 2022

Scientists develop virus-blocking textile that effectively repulses SARS-CoV-2

Scientists have described a virus-blocking textile that prevents transmission of SARS-CoV-2 via repulsive Coulomb force and human body triboelectric energy harvesting.

18 Mar 2022

Why does the SARS-CoV-2 Omicron variant escape immunity?

Researchers reveal the underlying mechanism associated with the Omicron variant’s increased transmissibility and ability to evade immunity.

17 Mar 2022

Immuno-metabolomic signatures that correlate with antigen-specific-T cell response during active COVID-19

Researchers investigate innate and adaptive immune responses at both the early and late stages of SARS-CoV-2 infection.

17 Mar 2022

Impact of new COVID vaccinations as novel variants emerge

Researchers explores the changing value of COVID-19 vaccines in a scenario of dynamic immunity and rapidly evolving variants of concern.

17 Mar 2022

BNT162b2 booster vaccination induces robust humoral and cellular immune responses

Scientists evaluate the humoral and cellular immune responses in individuals who have received a third booster dose of mRNA-based COVID-19 vaccine.

17 Mar 2022

Novel screening method detects new N501T SARS-CoV-2 variant

Researchers develop two SARS-CoV-2 Mutation Discrimination assays that have been designed to detect 501 and 484 mutations on the spike protein.

17 Mar 2022

Huddersfield researchers demonstrate how coronavirus activates the brain's immune response

Huddersfield researchers were among the first to demonstrate how the induction of brain inflammation accounts for neurological damage in COVID19 patients and now, their findings have been published in a peer-reviewed medical journal.

17 Mar 2022

Study reports thiopurines inhibit the replication of the betacoronaviruses HCoV-OC43 and SARS-CoV-2

Researchers demonstrated that the thiopurines block coronaviruses spike protein assembly and integration into progeny virions.

17 Mar 2022

MHRA authorizes new medicine for COVID-19 prevention

A new medicine, Evusheld (tixagevimab/cilgavimab), has today been authorised for COVID-19 prevention by the Medicines and Healthcare products Regulatory Agency (MHRA) after meeting the UK regulatory standards of safety, quality and effectiveness.

17 Mar 2022

Spike Protein News and Research

Molecular dynamic simulations unveil conformational dynamics of SARS-CoV-2 spike protein RBD and ACE2 receptor

Posaconazole found to be effective as a small molecule fusion inhibitor against SARS-CoV-2 variants

New research proves benefit of vaccination after recovery from COVID-19

Is COVID-19 on the verge of ending?

A circRNA COVID vaccine with potential to neutralize SARS-CoV-2 variants

Mount Sinai launches phase 1 study to evaluate the safety, immunogenicity of egg-based COVID-19 vaccine

Multiple inter-variant recombination events identified in Omicron subvariants

Response to COVID-19 boosters in seronegative multiple sclerosis patients

Omicron BA.1.1 and BA.2 subvariants with new mutations in New Zealand and Hong Kong

Acidity of expiratory aerosols influences infectivity of SARS-CoV-2

Texas Biomed and UAB partnership uncovers a new, potent antibody cocktail against all coronaviruses

Scientists develop virus-blocking textile that effectively repulses SARS-CoV-2

Why does the SARS-CoV-2 Omicron variant escape immunity?

Immuno-metabolomic signatures that correlate with antigen-specific-T cell response during active COVID-19

Impact of new COVID vaccinations as novel variants emerge

BNT162b2 booster vaccination induces robust humoral and cellular immune responses

Novel screening method detects new N501T SARS-CoV-2 variant

Huddersfield researchers demonstrate how coronavirus activates the brain's immune response

Study reports thiopurines inhibit the replication of the betacoronaviruses HCoV-OC43 and SARS-CoV-2

MHRA authorizes new medicine for COVID-19 prevention

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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