Stem Cells News and Research

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Stem cells have the remarkable potential to develop into many different cell types in the body during early life and growth. In addition, in many tissues they serve as a sort of internal repair system, dividing essentially without limit to replenish other cells as long as the person or animal is still alive. When a stem cell divides, each new cell has the potential either to remain a stem cell or become another type of cell with a more specialized function, such as a muscle cell, a red blood cell, or a brain cell.

Scientists solve long-standing puzzle about how breastfeeding women's bones remain strong

Researchers at UCSF and UC Davis solved a long-standing puzzle on how the bones of breastfeeding women stay strong even as they lose calcium to milk.

11 Jul 2024

High-intensity interval exercise improves brain function in older adults

A longitudinal study by University of Queensland researchers has found high-intensity interval exercise improves brain function in older adults for up to 5 years.

10 Jul 2024

Stem-like cells found to drive growth of aggressive pediatric brain tumors

A team of researchers at Baylor College of Medicine, Texas Children's Hospital, the Hospital for Sick Children in Toronto and collaborating institutions has identified and located a population of stem-like cells that initiates and maintains Group 3 medulloblastoma (Gr3-MB) in the developing brain.

9 Jul 2024

How does SARS-CoV-2 cause lymphopenia when T cells barely express ACE-2 receptors?

Researchers reveal both direct and indirect mechanisms of SARS-CoV-2-induced lymphopenia, highlighting the role of CD147 and alternative viral entry routes into T cells.

8 Jul 2024

Small molecule discovery offers hope for treatment of Angelman syndrome

Angelman syndrome is a rare genetic disorder caused by mutations in the maternally-inherited UBE3A gene and characterized by poor muscle control, limited speech, epilepsy, and intellectual disabilities.

8 Jul 2024

Breakthrough humanized mouse model offers new insights for immunotherapy development

A breakthrough for biomedical research promises new insight into immunotherapy development and disease modeling.

5 Jul 2024

New guidelines provide the first code of practice for use of stem cell-based embryo models

Stem cell-based embryo models (SCBEMs) are three-dimensional biological structures that mimic aspects of early human embryo development.

3 Jul 2024

New hope for solid tumors with enhanced CAR-T cells

A promising therapy that treats blood cancers by harnessing the power of the immune system to target and destroy cancer cells could now treat solid tumors more efficiently. Thanks to a recent study published in Molecular Therapy – Methods & Clinical Development from Dan Cappabianca and Krishanu Saha at the Wisconsin Institute for Discovery, Chimeric Antigen Receptor (CAR) T-cell therapy can be improved by altering the conditions the T cells are grown in. And it was all discovered by chance.

3 Jul 2024

Suppressing a protein turns ordinary fat into a calorie burner, study shows

New UCSF study shows that suppressing a protein turns ordinary fat into a calorie burner and may explain why drug trials attempting the feat haven't been successful.

1 Jul 2024

High-resolution real-time imaging reveals early developmental processes in quail embryos

Researchers at The University of Queensland have for the first time captured images and video in real time of early embryonic development to understand more about congenital birth defects.

1 Jul 2024

New study links psoriasis severity to skin microbiome dysbiosis

A multi-omics analysis of host-microbe interactions in psoriasis.

28 Jun 2024

Researchers identify key players in abnormal bone differentiation

A study conducted by researchers at Baylor College of Medicine and collaborating institutions reveals the molecular events leading to osteogenesis imperfecta type V, a form of brittle bone disease caused by a mutation in the gene IFITM5.

27 Jun 2024

Researchers uncover molecular signatures of blood-brain barrier dysfunction in Alzheimer's disease

The blood-brain barrier - a network of blood vessels and tissues that nurtures and protects the brain from harmful substances circulating in the blood - is disrupted in Alzheimer's disease.

26 Jun 2024

Beyond genes, new research explores mechanics and calcium signaling

Using animals to study heart disease doesn't always translate well to human health outcomes, and human heart cells available for research don't work outside the human body.

25 Jun 2024

Primitive endoderm in early embryos may be key to creating new effective fertility treatments

An unexpectedly versatile and regenerative stem cell in early embryos may be key to creating new effective fertility treatments, suggests a new study in mice from the University of Copenhagen.

24 Jun 2024

New study reveals the therapeutic potential of ZED1227 in celiac disease

A recent study led by researchers at Tampere University investigated whether a transglutaminase 2 inhibitor has potential as a drug to treat celiac disease.

24 Jun 2024

Hematopoietic stem cells in the bone marrow age differently in genetically identical mice

Our bone marrow - the fatty, jelly-like substance inside our bones - is an unseen powerhouse quietly producing 500 billion new blood cells every day.

21 Jun 2024

Role of SMIM1 gene in obesity uncovered

Scientists have discovered a new cause of why people who lack a specific blood group are genetically predisposed to be overweight or obese.

20 Jun 2024

Laser-based 3D bioprinting of corneas for vision restoration

Printing a new cornea during an operation to restore a patient's eyesight: This groundbreaking step in the fight against corneal disorders is set to become reality with a laser based process using personalized bioink.

19 Jun 2024

Mitophagy fuels cancer stem cell growth and survival

A new research paper was published on the cover of Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science) Volume 16, Issue 11, entitled, "Mitophagy and cancer: role of BNIP3/BNIP3L as energetic drivers of stemness features, ATP production, proliferation, and cell migration."

18 Jun 2024