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Unlocking the secrets of long-lived hematopoietic stem cells

Nothing lives forever, but compared to other cells in the body, hematopoietic stem cells (HSCs) are remarkably long-lived. HSCs are blood-forming cells – they give rise to rapidly dividing progenitor cells, which in turn generate hundreds of billions of cells to fulfill the daily demand of oxygen-delivering red blood cells, disease-fighting white blood cells and clot-forming platelets.

30 Apr 2024

Garvan Institute and Illumina collaborate to transform the treatment of complex diseases

Illumina, a global genomics and human health company, has partnered with the Garvan Institute of Medical Research's TenK10K project to help transform the treatment of complex diseases, starting with autoimmune diseases, with a joint investment of $27 million AUD.

30 Apr 2024

New monoclonal antibody vaccine slashes malaria risk in children

A recent study demonstrates that the monoclonal antibody-based vaccine L9LS is safe for children aged 6 to 10 and significantly reduces the risk of malaria infection and clinical symptoms by 70% and 77%, respectively.

30 Apr 2024

U of T researchers develop new approach for controlling neuron generation in Parkinson's disease

Researchers at the University of Toronto have found a way to better control the preclinical generation of key neurons depleted in Parkinson's disease, pointing toward a new approach for a disease with no cure and few effective treatments.

30 Apr 2024

Groundbreaking study reveals over 100 new genomic regions linked to blood pressure

National Institutes of Health researchers and collaborators have discovered over 100 new regions of the human genome, also known as genomic loci, that appear to influence a person's blood pressure.

30 Apr 2024

ZIP7: A novel target for treating degenerative diseases associated with misfolded proteins

Proteins are the workhorses of life. Organisms use them as building blocks, receptors, processors, couriers and catalysts.

30 Apr 2024

Deciphering the role of Th2-multipotent progenitor cells in chronic allergic inflammation

Currently, most therapies for allergic diseases require lifelong treatment. Allergic reactions, characterized by ongoing (type 2) inflammation in response to chronic antigen exposure, underlie many chronic diseases in humans, including asthma, atopic dermatitis, ulcerative colitis and more.

30 Apr 2024

Genetic propensity to higher arachidonic acid levels linked to lower bipolar disorder risk

A genetic propensity to higher circulating levels of lipids containing arachidonic acid, an omega-6 polyunsaturated fatty acid found in eggs, poultry, and seafood, has been found to be linked with a lower risk for bipolar disorder, according to a new study in Biological Psychiatry, published by Elsevier.

30 Apr 2024

Specific class of drugs can reverse diet-induced obesity, fatty liver and diabetes in mice

Researchers at Karolinska Institutet may have found a new way to treat obesity and related disorders by targeting the cells' powerhouses, the mitochondria.

30 Apr 2024

Wireless, bioresorbable, passive sensor for continuous pH monitoring and early identification of stomach leakage

A bioresorbable, cordless, passive sensor that monitors pH locally and detects stomach leakage early on.

30 Apr 2024

Asimov achieves 10x improvement in lentiviral production, launches new stable cell line development service

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30 Apr 2024

RNA editing using CRISPRs shows promise for genetic disease treatment

A team at Montana State University published research this week that shows how RNA, the close chemical cousin to DNA, can be edited using CRISPRs.

29 Apr 2024

New Kaposi sarcoma mouse model could be key to drug development

Researchers at UNC Lineberger Comprehensive Cancer Center, after decades of research efforts, have developed a mouse model of Kaposi sarcoma that could be key to the development of new drugs to treat the disease.

29 Apr 2024

Study reveals genetic divergence and drug resistance mechanisms in two critical superbugs

Infectious diseases caused by pathogenic strains of bacteria are a global cause of morbidity and mortality. Hospital-acquired infections caused by Klebsiella pneumonia and Pseudomonas aeruginosa were found vulnerable during the COVID-19 pandemic.

29 Apr 2024

Experimental monoclonal antibody prevents and reverses clinical type 1 diabetes in mice

Scientists at Johns Hopkins Medicine say that an experimental monoclonal antibody drug called mAb43 appears to prevent and reverse the onset of clinical type 1 diabetes in mice, and in some cases, to lengthen the animals' lifespan.

29 Apr 2024

Genetic associations of key genes in breast cancer pathogenesis

Breast cancer remains a significant global health concern, warranting further exploration into its genetic basis and potential therapeutic targets.

29 Apr 2024

Targeting skin microbiome rivals: Unveiling epilancin A37's antimicrobial mechanism

Many bacteria produce substances to gain an advantage over competitors in their highly competitive natural environment.

29 Apr 2024

Unlocking the mechanisms of pluripotent cell's fate determination

As embryos, all complex organisms are partially made up of pluripotent stem cells, a term for cells that have the capacity to differentiate into any kind of cell: nerve cells, muscle cells, blood cells, skin cells, and the like.

29 Apr 2024

Newly developed organoid model can be used to study thymus function

Researchers from the Organoid group have developed a new organoid model that can be used to study the thymus.

29 Apr 2024

Study reveals brown fat's built-in mechanism and potential obesity treatment

Brown fat, also known as brown adipose tissue (BAT), is a type of fat in our bodies that's different from the white fat around our belly and thighs that we are more familiar with.

29 Apr 2024

Cell News and Research

Unlocking the secrets of long-lived hematopoietic stem cells

Garvan Institute and Illumina collaborate to transform the treatment of complex diseases

New monoclonal antibody vaccine slashes malaria risk in children

U of T researchers develop new approach for controlling neuron generation in Parkinson's disease

Groundbreaking study reveals over 100 new genomic regions linked to blood pressure

ZIP7: A novel target for treating degenerative diseases associated with misfolded proteins

Deciphering the role of Th2-multipotent progenitor cells in chronic allergic inflammation

Genetic propensity to higher arachidonic acid levels linked to lower bipolar disorder risk

Specific class of drugs can reverse diet-induced obesity, fatty liver and diabetes in mice

Wireless, bioresorbable, passive sensor for continuous pH monitoring and early identification of stomach leakage

Asimov achieves 10x improvement in lentiviral production, launches new stable cell line development service

RNA editing using CRISPRs shows promise for genetic disease treatment

New Kaposi sarcoma mouse model could be key to drug development

Study reveals genetic divergence and drug resistance mechanisms in two critical superbugs

Experimental monoclonal antibody prevents and reverses clinical type 1 diabetes in mice

Genetic associations of key genes in breast cancer pathogenesis

Targeting skin microbiome rivals: Unveiling epilancin A37's antimicrobial mechanism

Unlocking the mechanisms of pluripotent cell's fate determination

Newly developed organoid model can be used to study thymus function

Study reveals brown fat's built-in mechanism and potential obesity treatment

Industry Focus eBook - Cell & Gene Therapy (1st Edition) eBook

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