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Study identifies new mechanism linking activation of key heart enzyme and oxidative stress

A study, led by University of Iowa researchers, reveals a new dimension for a key heart enzyme and sheds light on an important biological pathway involved in cell death in heart disease.

1 May 2008

Harmful blood glucose levels linked to genetic mutation

A genetic mutation that can raise the amount of glucose in a person's blood to harmful levels is identified today in a study in the journal Science.

1 May 2008

Does it matter that medical graduates don't get jobs as doctors?

In 2007, 1300 UK medical graduates were unable to secure training places, and this shortfall looks set to be repeated this year. But is this a betrayal of students' expectations or is this inevitable if patients are to get the best care?

1 May 2008

Poor nighttime sleep associated with daytime napping in older adults

Deficiencies in nighttime sleep are associated with daytime napping in older adults, according to a study published in the May 1 issue of the journal SLEEP.

1 May 2008

Breakthrough compound could lead to new class of antihypertensive drugs

University of Florida researchers have identified a drug compound that dramatically lowers blood pressure, improves heart function and - in a remarkable finding - prevents damage to the heart and kidneys in rats with persistent hypertension

1 May 2008

Short and long sleepers more likely to have metabolic syndrome

A study published in the May 1 issue of the journal SLEEP is the first known to report that short and long sleepers are more likely to have metabolic syndrome, or a combination of medical disorders that increase the risk of developing cardiovascular disease.

1 May 2008

Phase of clock gene expression in human leukocytes correlates with habitual sleep timing

The phase of clock gene expression in leukocytes, assessed in the absence of the masking effects of light-dark and sleep-wake cycles, correlates with habitual sleep timing, according to a study published in the May 1 issue of the journal SLEEP.

1 May 2008

Children's experiences in a pediatric intensive care unit

Nearly one in three children admitted to pediatric intensive care will experience delusions or hallucinations, which put them at higher risk for post-traumatic stress symptoms, according to a new study of children's experiences in a pediatric intensive care unit (PICU).

1 May 2008

Obesity and heart failure risk

Heart specialists at Johns Hopkins and elsewhere report what is believed to be the first wide-scale evidence linking severe overweight to prolonged inflammation of heart tissue and the subsequent damage leading to failure of the body's blood-pumping organ.

1 May 2008

New study raises questions about prostate cancer therapies targeting insulin-like growth factor receptor

Therapies under development to treat prostate cancer by inhibiting the ability of insulin-like growth factor (IGF-1) to activate its target receptor could have unexpected results especially if a major tumor suppressor gene - p53 - is already compromised, according to new research by investigators at Fred Hutchinson Cancer Research Center.

1 May 2008

Intensive training for medical staff in Latin American hospitals reduces serious complication of pregnancy

An intensive educational program for physicians and midwives involving 19 hospitals in Argentina and Uruguay dramatically reduced the rate of postpartum hemorrhage, according to researchers from the National Institutes of Health and other institutions.

1 May 2008

TV injury coverage lacking, study finds

Nearly every night, on nearly every TV station in the country, the local newscast features news of the day's car crashes, fires and other injury-causing events.

1 May 2008

High blood pressure still sneaking past doctors, Stanford study shows

Despite the well-known dangers of high blood pressure, major shortfalls still exist in the screening, treatment and control of the disease even when patients are getting a doctor's care, according to a study from the Stanford University School of Medicine.

1 May 2008

Dual treatment of incontinence and dementia associated with functional decline

Older nursing home residents who took medications for dementia and incontinence at the same time had a 50 percent faster decline in function than those who were being treated only for dementia, according to a study from researchers at Wake Forest University School of Medicine and colleagues.

1 May 2008

Scientists produce stem cells from ordinary mouse skin cells

Researchers in the United States say they have produced a stem cell made from ordinary mouse skin cells which they have coaxed into becoming three different types of heart and blood cells in mice.

1 May 2008

Early treatment of Helicobacter pylori infection may prevent cancer

Based on research using a new mouse model of gastritis and stomach cancer, researchers from the Massachusetts Institute of Technology (MIT) say that prompt treatment of Helicobacter pylori (H. pylori) infections reverses damage to the lining of the stomach that can lead to cancer.

1 May 2008

Obesity can worsen the impact of asthma

Obesity can worsen the impact of asthma and may also mask its severity in standard tests, according to researchers in New Zealand, who studied lung function in asthmatic women with a range of body mass indexes (BMIs).

1 May 2008

New discoveries in hearing health

Three studies published in the May 2008 edition of Otolaryngology - Head and Neck Surgery reveal substantial new findings in several areas of hearing health, including research that indicates that patients with profound hearing loss benefit substantially from having cochlear implants placed in both ears, rather than one, as is the common practice.

1 May 2008

New drug added to chemo kills off residual breast cancer stem cells

New research says chemotherapy often fails to totally eliminate breast cancer because it does not knock out breast cancer stem cells.

30 Apr 2008

Young children hospitalized for flu associated with higher costs and higher risk illness

The high costs of hospitalizing young children for influenza creates a significant economic burden in the United States, underscoring the importance of preventive flu shots for children and the people with whom they have regular contact, according to research led by Cincinnati Children's Hospital Medical Center and presented May 4 at the Pediatric Academic Society annual meeting in Honolulu, Hawaii.

30 Apr 2008