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Biochemists reveal interaction between tumor suppressor protein and chaperone

Every cell has thousands of proteins whose activity and lifetime must be regulated to control the cellular life cycle from cell division to cell death. The heat shock protein Hsp90 plays a key role in this process. It is a so-called chaperone, a quality controller, as it were. It monitors and controls the quality and activity of many important signal proteins and helps them take on the right form. When the cell is exposed to high stress levels from heat or a lack of oxygen, Hsp90 is produced in larger quantities to shield its partner proteins from damage.

8 Sep 2011

Adding azithromycin to usual daily treatment for COPD reduces acute exacerbations by 27%

Richard Casaburi, Ph.D., M.D., principal investigator at Los Angeles Biomedical Research Institute (LA BioMed), is co-author of a recent study that should help improve the condition for the millions of individuals who suffer from chronic obstructive pulmonary disease, better known as COPD.

8 Sep 2011

Majority of 9/11 World Trade Center attack survivors report increased incidence of GERS

Increased incidence of gastroesophageal reflux symptoms (GERS) reported by a large population of 9/11 World Trade Center attack survivors, most of whom had not reported any GERD-related symptoms prior to 9/11, worsened the health-related quality life for many rescue and recovery workers, lower-Manhattan residents and local workers who were exposed to the dust cloud and other contaminants in the aftermath of 9/11, according to a study published online today online today in The American Journal of Gastroenterology.

7 Sep 2011

St. Jude Medical's Genesis neurostimulation device receives European CE Mark approval

St. Jude Medical, Inc., a global medical device company, today announced it has received the industry's first and only regulatory approval for the use of an implanted neurostimulation device for patients with intractable chronic migraine.

7 Sep 2011

Biologists identify mechanism of H. pylori that damages DNA of gastric mucosal cells

The stomach bacterium Helicobacter pylori is one of the biggest risk factors for the development of gastric cancer, the third most common cause of cancer-related deaths in the world.

6 Sep 2011

Study aims to describe and understand current issues on OTC medicine addiction

A report of a study investigating over the counter medicine (OTC) abuse published by the Pharmacy Practice Research Trust provides evidence that there is a group of individuals experiencing a range of problems often with codeine-based medicines purchased from pharmacies, and for whom help and support varied.

5 Sep 2011

Alcohol related teen hospitalizations higher in areas with more off-licenses: Study

New research shows that the more off-license stores a town boasts of, the greater the number of under-age drinkers who are likely to end up in hospital as a result of harmful drinking.

5 Sep 2011

Researchers help explain elusive mechanics of complex cell transport system

Every cell in the human body contains a complex system to transport essential cargoes such as proteins and membrane vesicles, from point A to point B. These tiny molecular motor proteins move at blistering speeds on miniature railways carrying components of the cell to their proper destinations.

3 Sep 2011

Using high-speed lasers to zap mosquitoes in the fight against malaria

In this post on CNN's Global Public Square, journalist Amar Bakshi interviews Nathan Myhrvold, former chief technology officer of Microsoft and co-founder of Intellectual Ventures, about an anti-malaria project "that use[s] lasers and digital image processing techniques to not only find mosquitoes.

2 Sep 2011

RI Hospital researcher supports use of ablation procedures for treatment of lung cancer

The journal Radiology will publish in its September issue an article written by Damian E. Dupuy, M.D., director of tumor ablation at Rhode Island Hospital, supporting the use of ablation procedures for the treatment of lung cancer.

2 Sep 2011

Eisai announces results of perampanel Phase III study on epilepsy

Results presented today of a Phase III pivotal study for the investigational compound perampanel for partial-onset seizures showed that perampanel, 8 mg and 12 mg, produced statistically significant reductions in median seizure frequency compared to placebo among patients having partial-onset seizures while receiving treatment with one to three other epilepsy drugs.

31 Aug 2011

IntraPace to launch new lifestyle management portal and support network at IFSO 2011 congress

IntraPace, Inc., the developer of the innovative abiliti implantable obesity management system, announced today that it will launch its new lifestyle management portal and support network this week at the XVI World Congress of the International Federation for the Surgery of Obesity and Metabolic Disorders (IFSO) in Hamburg, Germany.

30 Aug 2011

AAO-HNSF's 2011 Annual Meeting & OTO EXPO to convene in San Francisco

The 2011 Annual Meeting & OTO EXPO of the American Academy of Otolaryngology - Head and Neck Surgery Foundation (AAO-HNSF), the largest meeting of ear, nose, and throat doctors in the world, will convene September 11-14, 2011, in San Francisco, CA.

29 Aug 2011

Astellas seeks regulatory approval for mirabegron to treat overactive bladder in the U.S., Europe

Astellas Pharma Inc. today announced the submission of a New Drug Application and Market Authorisation Application for mirabegron to the U.S. Food and Drug Administration and the European Medicines Agency.

29 Aug 2011

Azithromycin can help reduce wheezing, other acute symptoms of COPD

A common antibiotic can help reduce the severe wheezing and other acute symptoms of chronic obstructive pulmonary disease, according to a large, multicenter clinical trial sponsored by the National Institutes of Health and conducted at the University of California, San Francisco (UCSF).

29 Aug 2011

Frequency News and Research

Biochemists reveal interaction between tumor suppressor protein and chaperone

Adding azithromycin to usual daily treatment for COPD reduces acute exacerbations by 27%

Majority of 9/11 World Trade Center attack survivors report increased incidence of GERS

St. Jude Medical's Genesis neurostimulation device receives European CE Mark approval

Biologists identify mechanism of H. pylori that damages DNA of gastric mucosal cells

Study aims to describe and understand current issues on OTC medicine addiction

Alcohol related teen hospitalizations higher in areas with more off-licenses: Study

Researchers help explain elusive mechanics of complex cell transport system

Using high-speed lasers to zap mosquitoes in the fight against malaria

RI Hospital researcher supports use of ablation procedures for treatment of lung cancer

Eisai announces results of perampanel Phase III study on epilepsy

IntraPace to launch new lifestyle management portal and support network at IFSO 2011 congress

AAO-HNSF's 2011 Annual Meeting & OTO EXPO to convene in San Francisco

Astellas seeks regulatory approval for mirabegron to treat overactive bladder in the U.S., Europe

Azithromycin can help reduce wheezing, other acute symptoms of COPD

Early-morning cigarette smokers more likely to develop lung, head and neck cancers

New way to combat dengue fever

Allergan receives FDA approval for Botox to treat specific form of urinary incontinence

Smokers more likely to report problems with persistent musculoskeletal pain

Daily exercise can work as well as second antidepressant drug

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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