Antibodies News and Research

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New paper-based test can diagnose Zika infection within 20 minutes

MIT researchers have developed a paper-based test that can diagnose Zika infection within 20 minutes. Unlike existing tests, the new diagnostic does not cross-react with Dengue virus, a close relative of the Zika virus that can produce false positives on many Zika tests.

27 Sep 2017

High-speed method generates mini-protein binders with potential to become new class of drugs

Scientists have created a high-speed method to generate thousands of different, small, stable proteins from scratch that can be custom-designed to bind to specific therapeutic targets.

27 Sep 2017

First-ever treatment for Merkel cell carcinoma receives approval in Japan

Merck KGaA, Darmstadt, Germany, and Pfizer Inc. today announced that the Japanese Ministry of Health, Labor, and Welfare (MHLW) has approved BAVENCIO (avelumab, genetically recombinant Injection 200mg/mL for intravenous use) as the first and only treatment indicated for curatively unresectable Merkel cell carcinoma (MCC), a rare and aggressive cancer, in Japan.

27 Sep 2017

Cellular messaging mechanism could lead to new way of treating disease

A newly discovered cellular messaging mechanism could lead to a new way to deliver therapeutics to tissues affected by disease, according to a new study from Harvard T.H. Chan School of Public Health.

27 Sep 2017

Vaccine to prevent Lyme disease on the cards

Lyme disease is an infection that spreads with the bites of an infected tick. For the past four years, a vaccine to protect dogs from this disease has been available. Now, vaccinating humans against this disease has also become a possibility.

26 Sep 2017

Study: Antibody neutralizes dengue and Zika virus in mice

Brazil and other areas hardest hit by the Zika virus – which can cause babies to be born with abnormally small heads – are also home to dengue virus, which is spread by the same mosquito species.

25 Sep 2017

Triple-action antibody to be tested as HIV vaccine

Scientists from the National Institutes of Health (NIH) in collaboration with the pharmaceutical company Sanofi have engineered a three-pronged antibody that protected monkeys from two strains of Human Immunodeficiency Virus (HIV) better than the equivalent naturally occurring antibodies.

22 Sep 2017

New study shows how staph cells evade the body's immune system

For years, medical investigators have tried and failed to develop vaccines for a type of staph bacteria associated with the deadly superbug MRSA. But a new study by Cedars-Sinai investigators shows how staph cells evade the body's immune system, offering a clearer picture of how a successful vaccine would work.

21 Sep 2017

Small-molecule immunotherapeutics could steer immune defense against fungal pathogens

Fungal infections represent an increasing health crisis, especially for immune-deficient patients. American scientists now report in the journal Angewandte Chemie that specific help could be provided by small-molecule immunotherapeutics with novel mechanism of action.

21 Sep 2017

Researchers design novel small antibody fragment with improved crystallizability

Antibodies are a powerful weapon system in defending our body against invaders such as bacteria and viruses. Each antibody consists of four polypeptide chains: two heavy chains and two light chains joined to form a Y-shaped molecule.

21 Sep 2017

Researchers explore new combination approach to treat high-risk soft-tissue sarcomas

University of Maryland School of Medicine researchers are investigating a new approach to treat high-risk soft-tissue sarcomas by combining two immunotherapy drugs with radiation therapy to stimulate the immune system to destroy the main tumor as well as leftover microscopic cancer cells that may seed other tumors.

20 Sep 2017

'Small intestinal permeable peptides' improve biopharmaceuticals absorption in digestive tract

Biopharmaceuticals, medium- and high-molecular weight biologically active macromolecules, are not easily absorbed by the small intestine, the main organ responsible for gastrointestinal absorption, resulting in a bottleneck for oral administration type biopharmaceutical development.

20 Sep 2017

Researchers identify role of tumor-infiltrating B-cells in melanoma progression, resistance to therapy

In a multi-institutional collaborative study, scientists at The Wistar Institute and the Medical University of Vienna, Austria, have identified the role of tumor-infiltrating or tumor-associated B-cells ("TABs") in melanoma progression and resistance to targeted therapy.

20 Sep 2017

'Pocket' project develops new low-cost test for accurate TB detection

Tuberculosis (TB) is a major global health issue. According to the World Health Organisation (WHO), every year there are worldwide 8.8 million new active TB cases and nearly 2 million TB deaths - 5000 every day - mostly in the poorest communities of the developing world.

19 Sep 2017

Researchers identify potential gonorrhea vaccine candidates

Researchers at Oregon State University have identified a pair of proteins that show promise as the basis for a gonorrhea vaccine.

19 Sep 2017

VTT creates new portable device that measures inflammation levels quickly in home environment

VTT Technical Research Centre of Finland has developed a portable device for measuring inflammation levels quickly in home environment.

19 Sep 2017

Houston Methodist researchers find pathway for treating diseases caused by flesh-eating bacteria

Researchers at Houston Methodist have solved a 100-year-old mystery, providing them a possible key to unlock a pathway for treating diseases caused by flesh-eating bacteria. This is timely news, given the current dangers lurking in the debris and destruction left behind by Hurricane Harvey's floodwaters that destroyed tens of thousands of homes in Texas.

19 Sep 2017

Carbohydrates on surface of malaria parasites could be key to effective vaccine

An international research team has shown for the first time that carbohydrates on the surface of malaria parasites play a critical role in malaria's ability to infect mosquito and human hosts.

18 Sep 2017

Scientists make significant discovery in efforts to develop vaccine against global pathogens

Scientists at the University of Southampton have made a significant discovery in efforts to develop a vaccine against Zika, dengue and Hepatitis C viruses that affect millions of people around the world.

15 Sep 2017

KU Leuven researchers find that humans have lost ancient defense mechanism to combat viruses

Insects and plants have an important ancient defense mechanism that helps them to fight viruses. This is encoded in their DNA. Scientists have long assumed that vertebrates - including humans - also had this same mechanism. But researchers at KU Leuven, Belgium, have found that vertebrates lost this particular asset in the course of their evolution.

15 Sep 2017

Antibodies News and Research

New paper-based test can diagnose Zika infection within 20 minutes

High-speed method generates mini-protein binders with potential to become new class of drugs

First-ever treatment for Merkel cell carcinoma receives approval in Japan

Cellular messaging mechanism could lead to new way of treating disease

Vaccine to prevent Lyme disease on the cards

Study: Antibody neutralizes dengue and Zika virus in mice

Triple-action antibody to be tested as HIV vaccine

New study shows how staph cells evade the body's immune system

Small-molecule immunotherapeutics could steer immune defense against fungal pathogens

Researchers design novel small antibody fragment with improved crystallizability

Researchers explore new combination approach to treat high-risk soft-tissue sarcomas

'Small intestinal permeable peptides' improve biopharmaceuticals absorption in digestive tract

Researchers identify role of tumor-infiltrating B-cells in melanoma progression, resistance to therapy

'Pocket' project develops new low-cost test for accurate TB detection

Researchers identify potential gonorrhea vaccine candidates

VTT creates new portable device that measures inflammation levels quickly in home environment

Houston Methodist researchers find pathway for treating diseases caused by flesh-eating bacteria

Carbohydrates on surface of malaria parasites could be key to effective vaccine

Scientists make significant discovery in efforts to develop vaccine against global pathogens

KU Leuven researchers find that humans have lost ancient defense mechanism to combat viruses

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