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New method could revolutionize the delivery of antioxidants to stem cells

As we age, our bodies change and degenerate over time in a process called senescence. Stem cells, which have the unique ability to change into other cell types, also experience senescence, which presents an issue when trying to maintain cell cultures for therapeutic use.

27 Jun 2023

New technique shows potential to generically treat several kinds of cancer

Researchers led by Katsunori Tanaka at the RIKEN Cluster for Pioneering Research (CPR) in Japan and Hiromitsu Haba at the RIKEN Nishina Center for Accelerator-Based Science (RNC) have developed a new technique that has the potential to generically treat several kinds of cancer, with fewer negative side effects than currently available methods.

27 Jun 2023

GREB1 gene key to liver cancer development, study finds

The development of hepatocellular carcinoma, liver cancer, is known to involve abnormal activation of a signaling pathway called Wnt; however, the underlying mechanisms have not been fully understood, until now.

27 Jun 2023

Growing up in poverty may influence the wiring of a child's brain, study suggests

A new study from Washington University School of Medicine in St. Louis suggests that growing up in poverty may influence the wiring of a child's brain.

27 Jun 2023

Mastering repeatability in cell culture with INTEGRA Biosciences’ WELLJET peristaltic pump dispenser

INTEGRA Biosciences’ WELLJET reagent dispenser and EasySnap™ dispensing cassettes offer a unique solution to common issues in cell-based workflows.

From INTEGRA Biosciences 27 Jun 2023

New nanocarriers could revolutionize tuberculosis treatment

Therapy of the dangerous infectious disease of tuberculosis faces the challenge of pathogens frequently being resistant to several common antibiotics.

27 Jun 2023

Are a high-refined carbohydrate diet and the alterations resulting from its intake linked to small intestine changes?

Researchers investigated whether a high-refined carbohydrate diet and associated metabolic alterations could cause small intestinal dysregulation.

27 Jun 2023

mRNA rabies vaccine induces durable immune response in macaques

Novel mRNA vaccine for rabies shows enhanced immune response with higher antibody levels and improved cross-neutralization, indicating potential for a broadly protective vaccine against related lyssavirus strains.

26 Jun 2023

New study offers clues on how to future-proof covid-19 vaccines

New research examining how frequently our bodies produce broadly neutralizing antibodies (bnAbs) capable of thwarting a range of SARS-CoV-2 variants offers clues on the strategy tweaks that could potentially future-proof COVID-19 vaccines.

26 Jun 2023

New study shows promise for diphenyl ditelluride as anti-cancer drug

A new research paper was published in Oncotarget's Volume 14 on June 21, 2023, entitled, "Diphenyl ditelluride anticancer activity and DNA topoisomerase I poisoning in human colon cancer HCT116 cells."

26 Jun 2023

Novel biomaterials approach reveals how mechanical forces shape T cell fate

The successful campaign of adoptive T cell therapies, a type of immunotherapy in which immune T cells are collected from a patient, enhanced outside of the body, and reinfused back into the same patient, especially against blood cancers is well under way.

26 Jun 2023

New kidney cancer model highlights molecular targets and genomic events that drive metastasis

Researchers at The University of Texas MD Anderson Cancer have engineered a new model of aggressive renal cell carcinoma (RCC), highlighting molecular targets and genomic events that trigger chromosomal instability and drive metastatic progression.

26 Jun 2023

Researchers pinpoint a key feature that leads to aggressive spread of colon cancer

In a significant development in the fight against fatal cancers, University of Otago researchers have pinpointed a key feature that leads to the aggressive spread of colon cancer.

26 Jun 2023

UCalgary researchers discover how Leishmania parasites hide within the body

University of Calgary researchers have discovered how Leishmania parasites hide within the body to cause Leishmaniasis. The tiny parasites are carried by infected sand flies.

26 Jun 2023

Study sheds new light on the relationship between gut microbiome and autism

The biological roots of autism continue to perplex researchers, despite a growing body of studies looking at an increasing array of genetic, cellular and microbial data.

26 Jun 2023

Scientists identify potential biomarkers associated with positive immunotherapy response

Scientists at the UCLA Jonsson Comprehensive Cancer Center have identified potential new biomarkers that could indicate how someone diagnosed with metastatic melanoma will respond to immunotherapy treatment.

26 Jun 2023

New study warns of dangers of gene editing in human embryos

Scientists have discovered that the cells of early human embryos are often unable to repair damage to their DNA.

26 Jun 2023

Innovative nanofluidic device detects single proteins at their naturally high concentrations

In the evolving world of precision medicine, the need for methods that can measure biomolecules with supreme accuracy and specificity is paramount. Recognizing this, Associate Professor Yan Xu of the Graduate School of Engineering at Osaka Metropolitan University and his international research team have made a great stride in this direction. They have developed an innovative nanofluidic device capable of capturing single proteins stochastically and detecting them digitally at their naturally high concentrations. This breakthrough could potentially lay the foundation for the future of personalized disease prevention and treatment.

26 Jun 2023

Senescent cells unlock the secret to luscious hair growth

The study findings indicate a peculiar pathway of regulation of hair growth by hair stem cells that is mediated by dermal melanocytes in senescence.

25 Jun 2023

Histone acetyltransferases: Promising targets for cancer treatment

Announcing a new publication for Acta Materia Medica journal. Histone lysine acylation is a major class of histone post-translational modifications involved in essential biological activities, such as transcriptional regulation, DNA-damage, a repairnd cell-cycle progression.

25 Jun 2023