Genes News and Research

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Molecular surveillance of SARS-CoV-2 spike protein mutations using CovRadar

In a recent bioRxiv preprint research paper, scientists from Germany discuss how they made sequence information more easily accessible for epidemiologists and virologists.

7 Feb 2021

Study shows how bacteriophage lysis genes could be key to developing new antibiotics

A study from the Center for Phage Technology, part of Texas A&M's College of Agriculture and Life Sciences and Texas A&M AgriLife Research, shows how the "hidden" genes in bacteriophages -- types of viruses that infect and destroy bacteria -- may be key to the development of a new class of antibiotics for human health.

7 Feb 2021

How does SARS-CoV-2 infect the pancreas?

To understand how SARS-CoV-2 infects the pancreas and investigate its effects, a team of researchers used the human iPSC (induced pluripotent stem cells)-derived pancreatic cultures and analyzed the post-infection cellular and molecular changes.

5 Feb 2021

Targeted pulses of ultrasound can help treat a range of brain diseases

Ultrasound is not only used as an imaging technique but targeted pulses of ultrasound can be used as a highly accurate treatment for a range of brain diseases, for which there were previously only limited treatment options.

5 Feb 2021

GLS1 inhibitor selectively eliminates senescent cells, ameliorates age-associated disorders

Senescent cells accumulate in organs during aging, promote tissue dysfunction, and cause numerous aging-related diseases like cancer. The cells arise through a process called "cellular senescence," a permanent cell cycle arrest resulting from multiple stresses.

5 Feb 2021

Gene panel test enables highly accurate diagnosis of liposarcomas

Researchers have leveraged the latest advances in RNA technology and machine learning methods to develop a gene panel test that allows for highly accurate diagnosis of the most common types of liposarcoma.

5 Feb 2021

Study indicates that 2019-2020 flu season was driven by a new, more transmissible strain

The 2019-2020 flu season in the U.S. was unusual in a number of ways. Cases picked up in August rather than the more typical fall and early winter months, and it hit children particularly hard. It was also dominated early on by a Type B influenza virus instead of one of the much more common Type A viruses like H1N1 or H3N2.

5 Feb 2021

Fecal transplant overcomes resistance to immunotherapy in melanoma patients

Researchers at UPMC Hillman Cancer Center and the National Cancer Institute demonstrate that changing the gut microbiome can transform patients with advanced melanoma who never responded to immunotherapy - which has a failure rate of 40% for this type of cancer - into patients who do.

5 Feb 2021

Men’s understanding of fertility awareness has been largely understudied, shows study

'I think children are cute', 'the future of our world looks bleak' — why men choose to have or not to have children has been investigated by a Malmö University researcher.

5 Feb 2021

Emory MVA COVID-19 vaccine proven safe and effective in mice and monkeys

Researchers at Yerkes National Primate Research Center, Emory University, have developed a COVID-19 vaccine that has proven safe and effective in mice and monkeys.

4 Feb 2021

Paternal early life stress linked to child's brain development

The FinnBrain research of the University of Turku has demonstrated for the first time that the stress the father has experienced in his childhood is connected to the development of the white matter tracts in the child's brain.

4 Feb 2021

Gut microbiome can modulate the immune response in liver cancer patients with NAFLD

The distinctive gut microbiome profile of a person with liver cancer linked to non-alcoholic fatty liver disease (NAFLD) could be the key to predicting someone's risk of developing the cancer, say researchers from the UNSW Microbiome Research Centre.

4 Feb 2021

Songbird system may provide new treatment options for children with autism

Inactivating a gene in young songbirds that are closely linked with autism spectrum disorder (ASD) prevents the birds from forming memories necessary to accurately reproduce their fathers' songs, a new study led by UT Southwestern shows.

4 Feb 2021

Sulforaphane prolongs lifespan and healthspan of C. elegans through insulin/IGF-1 signaling

Aging-US published "Sulforaphane promotes C. elegans longevity and healthspan via DAF- 16/DAF-2 insulin/IGF-1 signaling" which reported that the broccoli-derived isothiocyanate sulforaphane inhibits inflammation, oxidative stress and cancer, but its effect on healthspan and longevity are unclear.

4 Feb 2021

Study shows how tissue damage promotes the earliest stages of pancreatic cancer

Like weeds sprouting from cracks in the pavement, cancer often forms in sites of tissue damage. That damage could be an infection, a physical wound, or some type of inflammation.

4 Feb 2021

Spark Therapeutics launches gene therapy clinical trial for late-onset Pompe disease

Pompe disease is a hereditary genetic disorder caused by a deficiency of acid alpha-glucosidase leading to build-up of glycogen in the lyosomes, which then causes cell damage in various tissues, in particular the heart, the muscles, the liver and the nervous system.

3 Feb 2021

Study gives new clues to how muscle wasting occurs on a cellular level

Muscle wasting, or the loss of muscle tissue, is a common problem for people with cancer, but the precise mechanisms have long eluded doctors and scientists. Now, a new study led by Penn State researchers gives new clues to how muscle wasting happens on a cellular level.

3 Feb 2021

Phase 1 clinical trial of novel HIV vaccine approach shows promising results

A phase 1 clinical trial testing a novel vaccine approach to prevent HIV has produced promising results, IAVI and Scripps Research announced today.

3 Feb 2021

Combining PD-1 and VEGF inhibitors with chemotherapy can help control cholangiocarcinoma

Cholangiocarcinoma (CCA) is considered as a diverse group of epithelial cancers characterized by poor outcomes. Cholangiocarcinoma can be divided into three types according to the original position: Intrahepatic Cholangiocarcinoma (ICC), Perihilar Cholangiocarcinoma (PCC), and Distal Extrahepatic Tumors (DET).

3 Feb 2021

Study: Brain hormones could improve metabolism and fight obesity

A mitochondrial hormone expressed by cells deep in the brain appears to play a role in improving metabolism and fighting off obesity, according to a new study in mice.

3 Feb 2021

Genes News and Research

Molecular surveillance of SARS-CoV-2 spike protein mutations using CovRadar

Study shows how bacteriophage lysis genes could be key to developing new antibiotics

How does SARS-CoV-2 infect the pancreas?

Targeted pulses of ultrasound can help treat a range of brain diseases

GLS1 inhibitor selectively eliminates senescent cells, ameliorates age-associated disorders

Gene panel test enables highly accurate diagnosis of liposarcomas

Study indicates that 2019-2020 flu season was driven by a new, more transmissible strain

Fecal transplant overcomes resistance to immunotherapy in melanoma patients

Men’s understanding of fertility awareness has been largely understudied, shows study

Emory MVA COVID-19 vaccine proven safe and effective in mice and monkeys

Paternal early life stress linked to child's brain development

Gut microbiome can modulate the immune response in liver cancer patients with NAFLD

Songbird system may provide new treatment options for children with autism

Sulforaphane prolongs lifespan and healthspan of C. elegans through insulin/IGF-1 signaling

Study shows how tissue damage promotes the earliest stages of pancreatic cancer

Spark Therapeutics launches gene therapy clinical trial for late-onset Pompe disease

Study gives new clues to how muscle wasting occurs on a cellular level

Phase 1 clinical trial of novel HIV vaccine approach shows promising results

Combining PD-1 and VEGF inhibitors with chemotherapy can help control cholangiocarcinoma

Study: Brain hormones could improve metabolism and fight obesity

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