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Researchers identify cells that cause nervous system disease

Two teams of University of Michigan researchers have tracked down the cells responsible for neurofibromatosis type1, a disfiguring, incurable condition and one of the most common hereditary disorders.

4 Feb 2008

Researchers uncover key interaction in cholesterol regulation

Researchers at UT Southwestern Medical Center have determined the specific way in which a destructive protein binds to and interferes with a molecule that removes low-density lipoproteins (LDL), the so-called "bad" cholesterol, from the blood.

4 Feb 2008

Targeting astrocytes slows progression of Lou Gehrig's disease

In what the researchers say could be promising news in the quest to find a therapy to slow the progression of amyotrophic lateral sclerosis (ALS), or Lou Gehrig’s disease, scientists at the University of California, San Diego (UCSD) School of Medicine have shown that targeting neuronal support cells called astrocytes sharply slows disease progression in mice.

4 Feb 2008

Gene expression in meningiomas may vary by hormone receptor status

An association between hormones and meningioma has long been postulated, but the specific nature of this relationship has remained unclear.

4 Feb 2008

Scientists recreate rhinovirus infection in mice - hope of new asthma treatments

Scientists have been able to recreate rhinovirus infection, which is behind most common colds, in a small animal for the first time.

4 Feb 2008

Video games activate reward regions of brain in men more than women

Allan Reiss, MD, and his colleagues have a pretty good idea why your husband or boyfriend can't put down the Halo 3. In a first-of-its-kind imaging study, the Stanford University School of Medicine researchers have shown that the part of the brain that generates rewarding feelings is more activated in men than women during video-game play.

4 Feb 2008

FDA approves only once-daily inhaled corticosteroid for children

Schering-Plough Corporation has announced that the U.S. Food and Drug Administration (FDA) has approved ASMANEX TWISTHALER 110 mcg (mometasone furoate inhalation powder) for the maintenance treatment of asthma as a preventive therapy in patients 4 to 11 years of age.

4 Feb 2008

Infants' bodies expel thimerosal mercury much faster than originally thought

February's issue of Pediatrics offers another reason to rethink blaming the spike in autism diagnoses on thimerosal, a mercury-containing preservative routinely used in several childhood vaccines until the late '90s.

4 Feb 2008

Novel treatment for blood clots in the legs appears to be safe and effective

The study found that injecting or “lacing” the clot with a fiber-binding thrombolytic agent effectively treats deep vein thrombosis (DVT) and reduces the risk of subsequent recurrence or bleeding.

4 Feb 2008

Researchers use DNA to drive the assembly of 3D gold structures

DNA is the blueprint of all life, giving instruction and function to organisms ranging from simple one-celled bacteria to complex human beings.

4 Feb 2008

Protein, macrophage migration inhibitory factor predicts heart attack response and cardiac damage

A protein has been found that influences the response of the heart to a lack of oxygen and blood flow, such as occurs during a heart attack, a team of Yale School of Medicine researchers report in Nature.

4 Feb 2008

Government dietary guidelines, unintended consequences and public policy

In the years following the government promotion of a low-fat diet, obesity in America has reached almost epidemic levels.

4 Feb 2008

Porous structures help boost integration of host tissue with implants

Results published in FASEB (the journal of the Federation of American Societies for Experimental Biology) by researchers at Columbia University, including Jeremy Mao of the Columbia College of Dental Medicine, demonstrate a novel way of using porous structures as a drug-delivery vehicle that can help boost the integration of host tissue with surgically implanted titanium.

4 Feb 2008

New target for flu prevention

Emerging subtypes of influenza A virus hold the potential to initiate a world-wide epidemic in the next few years, according to World Health Organization officials.

4 Feb 2008

Zinc may offer protection against cadmium exposure

Cadmium exposure is a known risk factor for prostate cancer, and a new University of Rochester study suggests that zinc may offer protection against cadmium.

4 Feb 2008

Researchers seek trial participants for experimental HIV vaccine called PENNVAX-B

University of Pennsylvania School of Medicine researchers are recruiting healthy, HIV-negative adults to participate in a phase I clinical trial of an experimental HIV vaccine called PENNVAX-B, a DNA-based vaccine which is made using synthetic DNA-based HIV genes.

4 Feb 2008

Best way to treat abdominal aortic aneurysms

Abdominal aortic aneurysm (AAA) - a condition in which the large vessel that supplies blood to your abdomen, legs, and pelvis swells to over 50 percent its normal size -occurs in approximately 4 out of 100 adults.

4 Feb 2008

Advances in age-related macular degeneration treatment

A new study of age-related macular degeneration (AMD), a disease that affects more than nine million Americans, will pave the way for the biopharmaceutical industry to develop better treatments and cures, according to the Foundation Fighting Blindness, which partially funded the research.

4 Feb 2008

Study looks at safe dosages of the isotope astatine-211 for brain tumors

In a study to determine safe dosages of the isotope astatine-211 for patients with recurring brain tumors, researchers were pleasantly surprised to find that not only was the isotope's potency sufficient to kill residual cancer cells without damaging sensitive healthy brain cells, but the patients experienced longer survival rates.

4 Feb 2008

March of Dimes works to eliminate racial gaps in infant health

In recognition of Black History Month, the March of Dimes is drawing attention to the tremendous gap in premature birth and infant mortality rates that disproportionately affect black women in the United States and to the programs and research designed to reduce -- and one day eliminate -- these disparities.

4 Feb 2008