Bone News and Research

RSS

Targeting RAD52 protein can block the process by which leukemia stem cells repair themselves

Despite treatment with imatinib, a successful drug that targets chronic myeloid leukemia (CML), a deadly type of cancer, some patients may continue to be at risk for relapse because a tiny pool of stem cells is resistant to treatment and may even accumulate additional genetic aberrations, eventually leading to disease progression and relapse. These leukemia stem cells are full of genetic errors, loaded with potentially lethal breaks in DNA, and are in a state of constant self-repair.

10 Dec 2012

IDSA guidelines describe best methods for diagnosis of prosthetic joint infections

Of the one million people each year who get hips and knees replaced, as many as 20,000 will get an infection in the new joint, a number that is expected to skyrocket in the next 20 years. Multispecialty physician teams need to work together to reduce disability, death and costs associated with the ever-growing number of these prosthetic joint infections, note the first guidelines on the topic being released by the Infectious Diseases Society of America (IDSA).

9 Dec 2012

C5aRA treatment could be effective against periodontitis

Periodontitis, a form of chronic gum disease that affects nearly half of the U.S. adult population, results when the bacterial community in the mouth becomes unbalanced, leading to inflammation and eventually bone loss. In its most severe form, which affects 8.5 percent of U.S. adults, periodontitis can impact systemic health.

9 Dec 2012

Prosthetic joint infection guidelines released

The Infectious Diseases Society of American has released guidelines for the diagnosis and care of patients with a prosthetic joint infection.

7 Dec 2012

Study identifies epigenetic events critical to cancer cell survival

USC Norris Comprehensive Cancer Center research that identifies specific genes that have to be turned off in order for cancer cells to survive was named one of the top major advances in cancer research this year by the American Society of Clinical Oncology (ASCO).

7 Dec 2012

Gene therapy could represent new treatment option for severe orthopaedic injuries

Gene therapy involving modified stem cells obtained from fatty tissue and bone marrow could represent a new option for the treatment of severe orthopaedic injuries to the extremities.

7 Dec 2012

Teenage girls who smoke may put themselves at risk for osteoporosis

Adolescent girls who smoke between the ages of 11 and 19 years may be putting themselves at increased risk for osteoporosis in older age, suggest study results.

6 Dec 2012

Tenofovir DF safe and effective in treating adolescents with HBV

A recent clinical trial found that the adult antiviral drug, tenofovir disoproxil fumarate (tenofovir DF), is safe and effective in treating adolescents with hepatitis B virus (HBV). Trial results published in the December issue of Hepatology, a journal of the American Association for the Study of Liver Diseases (AASLD), show that tenofovir DF suppressed HBV in 89% of pediatric participants.

6 Dec 2012

Study provides important data about fertility window of women with childhood cancer

This study provided important data about the fertility window of women who had suffered from childhood cancer and information concerning the associated risk factors, but did not confirm the greater risk of premature menopause (before the age of 40) that was reported by the American studies.

5 Dec 2012

New method can generate stable human mesenchymal stem cells for bone engineering

Human mesenchymal stem cells (hMSCs) can develop into bone cells and are useful for tissue engineering and regeneration. However, when grown in the laboratory they quickly lose their ability to continue dividing and they die.

5 Dec 2012

New data from AstraZeneca's FASLODEX studies on breast cancer to be presented at SABSC

AstraZeneca today announced the presentation of important new data from studies of FASLODEX (fulvestrant) Injection at the 2012 CTRC-AACR San Antonio Breast Cancer Symposium taking place from 4-8 December at the Henry B. Gonzalez Convention Center, San Antonio, Texas.

5 Dec 2012

UIC researcher to investigate whether mechanical forces can increase bone strength

Bone strength is important to aging well, but doctors and therapists are far from understanding the best way to maintain healthy bone or what kind of exercise might help, according to University of Illinois at Chicago College of Applied Health Sciences researcher Karen Troy.

5 Dec 2012

Study explores osteoporosis racial differences in women

About 30 million women in the U.S. have osteoporosis, with low bone mass and deteriorating bone structure that increases their risk for fractures. Racial differences in the rates of detection and management of osteoporosis were explored in a study of African American and white women published in Journal of Women's Health, a peer-reviewed publication from Mary Ann Liebert, Inc., publishers.

5 Dec 2012

Cabozantinib effectively treats prostate cancer spread to bones

A new drug demonstrated dramatic and rapid effects on prostate cancer that had spread to the bone, according to a study reported by University of Michigan Comprehensive Cancer Center researchers.

5 Dec 2012

EC grants CE mark to InSightec’s ExAblate Neuro ultrasound system

InSightec Ltd. announced that its transcranial focused ultrasound system, ExAblate Neuro, has been awarded the European CE mark for the treatment of neurological disorders in the brain including essential tremor, Parkinson's disease and neuropathic pain.

4 Dec 2012

Virginia Women's Center to participate in new HPV and cervical cancer vaccine clinical trial

Virginia Women's Center has been selected to participate in a nationwide clinical trial, one that will ultimately hope to prevent the human papillomavirus virus (HPV) from progressing into cervical cancer and treat women who have HPV and the precancerous lesions associated with it. The Richmond-area OB-GYN practice has participated in over 50 clinical research studies since 1997, all of which have contributed to the future of safe and effective medicine for women.

4 Dec 2012

InSightec receives European CE mark for ExAblate Neuro system

Elbit Imaging Ltd. announced today that on December 3, 2012, Elbit Medical Technologies Ltd., announced that InSightec Ltd. has been awarded the European CE mark for its transcranial focused ultrasound system, ExAblate Neuro, with respect to the treatment of neurological disorders in the brain, including essential tremor, Parkinson's disease and neuropathic pain.

4 Dec 2012

Researchers derive dopaminergic neurons from bone marrow stem cells in monkeys

Parkinson's disease is a degenerative disorder of the central nervous system that is characterized by tremors, rigidity, slowness of movement, and difficulty walking. It is caused by loss of the neurons that produce the neurotransmitter dopamine (known as dopaminergic neurons). One of the primary goals in Parkinson's disease research is to develop a replacement for dopaminergic neurons.

4 Dec 2012

Feeding probiotics to baby zebrafish accelerates their development into adulthood

Probiotics like those found in yogurt are not only good for people--they are also good for fish. A new study by scientists at the Institute of Marine and Environmental Technology found that feeding probiotics to baby zebrafish accelerated their development and increased their chances of survival into adulthood.

4 Dec 2012

Link between smoking, decreased bone density and osteoporosis risk in teenage girls

Teenage girls who smoke accumulate less bone during a critical growth period and carry a higher risk of developing osteoporosis later in life, according to new research in the Journal of Adolescent Health.

4 Dec 2012

Bone News and Research

Targeting RAD52 protein can block the process by which leukemia stem cells repair themselves

IDSA guidelines describe best methods for diagnosis of prosthetic joint infections

C5aRA treatment could be effective against periodontitis

Prosthetic joint infection guidelines released

Study identifies epigenetic events critical to cancer cell survival

Gene therapy could represent new treatment option for severe orthopaedic injuries

Teenage girls who smoke may put themselves at risk for osteoporosis

Tenofovir DF safe and effective in treating adolescents with HBV

Study provides important data about fertility window of women with childhood cancer

New method can generate stable human mesenchymal stem cells for bone engineering

New data from AstraZeneca's FASLODEX studies on breast cancer to be presented at SABSC

UIC researcher to investigate whether mechanical forces can increase bone strength

Study explores osteoporosis racial differences in women

Cabozantinib effectively treats prostate cancer spread to bones

EC grants CE mark to InSightec’s ExAblate Neuro ultrasound system

Virginia Women's Center to participate in new HPV and cervical cancer vaccine clinical trial

InSightec receives European CE mark for ExAblate Neuro system

Researchers derive dopaminergic neurons from bone marrow stem cells in monkeys

Feeding probiotics to baby zebrafish accelerates their development into adulthood

Link between smoking, decreased bone density and osteoporosis risk in teenage girls

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Latest News