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Collaboration to improve the UK's health

A collaboration between the Universities of Bristol, Cardiff and Swansea has been awarded £5 million by the UK Clinical Research Collaboration (UKCRC) to establish a Centre of Excellence for research into public health.

29 Jan 2008

Smaller pancreatic tumors greatly increase survival odds

The odds of surviving cancer of the pancreas increase dramatically for patients whose tumors are smallest, according to a new study by researchers at Saint Louis University and the M.D. Anderson Cancer Center in Houston - the first study to specifically evaluate the link between tumor size and survival rates for one of the most common and deadly cancers.

28 Jan 2008

Evidence strongly supports diuretics as initial metabolic syndrome therapy, especially in black patients

New research shows that in people with high blood pressure as part of metabolic syndrome, a cluster of conditions that increases the risk for heart disease, diuretics offer greater protection against cardiovascular disease, including heart failure, and are at least as effective for lowering blood pressure as newer, more expensive medications.

28 Jan 2008

Unexpected protein-protein interaction suggests new ALS drug target

Discovery of an unexpected protein-protein interaction has led University of Iowa scientists and colleagues to identify a drug that slows the progression of Amyotrophic Lateral Sclerosis (ALS) in mice and nearly doubles the animals' lifespan.

25 Jan 2008

Celebrex may disrupt heart rhythm

Celebrex, a popular arthritis drug that blocks pain by inhibiting an enzyme known as COX-2, has been shown in laboratory studies to induce arrhythmia, or irregular beating of the heart, via a novel pathway unrelated to its COX-2 inhibition.

25 Jan 2008

Quitting marijuana as hard as quitting cigarettes

Research by a group of scientists studying the effects of heavy marijuana use suggests that withdrawal from the use of marijuana is similar to what is experienced by people when they quit smoking cigarettes.

25 Jan 2008

Building stronger bones, one stem cell at a time

Mesenchymal stem cells (MSCs) are bone marrow-derived cells that are capable of giving rise to various cell types through a process known as differentiation.

25 Jan 2008

Study paves way for mass co-delivery of three antiparasitic drugs

Findings from a new study in Zanzibar, published January 23 in PLoS Neglected Tropical Diseases, pave the way for the World Health Organization (WHO) to recommend the mass co-delivery of three anti-parasitic drugs for the first time.

24 Jan 2008

New approach to gene therapy

RNA interference (RNAi) represents an innovative new strategy for using small RNA molecules to silence specific genes associated with disease processes, and a series of review articles describing the state-of-the-art and potential therapeutic applications of RNAi and microRNAs will begin with two review papers in the January 2008 issue (Volume 19, Number 1) of Human Gene Therapy, a peer-reviewed journal published by Mary Ann Liebert, Inc.

24 Jan 2008

Synthesis of natural molecule could lead to better anti-cancer drugs

In early 2007, Northwestern University chemist Karl Scheidt's interest was piqued when marine chemist Amy Wright reported in the Journal of Natural Products that a new natural compound derived from an uncommon deep-sea sponge was extremely effective at inhibiting cancer cell growth.

24 Jan 2008

Stanford study finds transplant patient thrives 2 years after stopping immunosuppressive drugs

Luck smiled on Larry Kowalski when his brother agreed to donate a kidney Kowalski needed to live.

24 Jan 2008

OTC cough medicine: Not worthwhile for children or adults?

Alert parents know that small children should not take over-the-counter cough medications.

24 Jan 2008

One third of stunting and a quarter of deaths among under 3s in poor countries could be prevented

If existing maternal and child nutrition interventions were implemented in poor countries, cases of stunting among under 3s could be reduced by a third, and deaths by up to a quarter, according to new research being published today.

24 Jan 2008

Northwestern Memorial trial may wean kidney transplant patients off antirejection drugs

After a transplant surgery, anti-rejection drugs for the organ recipient are a must, but with prolonged use can have serious side effects, including infections, heart disease and cancer.

24 Jan 2008

No clear evidence that antidepressants assist in the management of chronic low back pain

Doctors commonly prescribe antidepressants for patients with low back pain for three main reasons; to relieve pain; reduce mild depression and improve a person's mood; and improve sleep.

24 Jan 2008

Less education may lead to delayed awareness of Alzheimer's onset

A review of epidemiological data has found evidence that people who spend fewer years in school may experience a slight but statistically significant delay in the realization that they're having cognitive problems that could be Alzheimer's disease.

24 Jan 2008

Health insurance co-payments deter mammography use

When faced with even a modest health insurance co-payment for a mammogram, significantly fewer women receive these potentially life-saving breast cancer screenings, according to a new study by Brown University and Harvard Medical School researchers.

24 Jan 2008

Hawthorn extract helps the heart

Taking hawthorn extract can help control symptoms of chronic heart disease such as low abilities to work and walk, and also improve a range of heart-related measurements.

24 Jan 2008

Few strategies exist to prevent MRSA spread in nursing homes

Methicillin-resistant Staphylococcus aureu (MRSA) is making news as a dangerous, sometimes fatal disease for hospital patients, and in recent cases, students.

24 Jan 2008

Experimental procedure induces tolerance to mismatched kidney transplants

Four of five patients participating in a trial of an experimental protocol designed to induce immune tolerance to HLA-mismatched kidney transplants have been able to discontinue immunosuppressive drugs.

24 Jan 2008