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Seaside Therapeutics reports positive data from STX209 Phase 2 study in fragile X syndrome

Seaside Therapeutics, Inc. announced today data from the largest randomized, placebo-controlled study conducted to date in individuals with fragile X syndrome. In a Phase 2 study of STX209, clinically meaningful improvements on global and specific neurobehavioral outcomes were observed in the general study population. The improvements were statistically significant in pediatric patients with more severe impairments in sociability -- a core symptom of fragile X syndrome.

26 Jul 2010

Brainlab launches ExacTrac Infrared Monitoring device for patient positioning during radiation therapy

Brainlab announced the availability of ExacTrac® Infrared Monitoring, an add-on device to existing treatment machines for monitoring patient positioning during radiation therapy treatments, at the American Association of Physicists in Medicine (AAPM) Annual Meeting last week.

26 Jul 2010

Obesity linked to early puberty in girls

A review of more than 100 studies found overweight girls tend to reach puberty earlier than their peers do.

26 Jul 2010

Boston Scientific launches Neuroform EZ Stent System

Boston Scientific Corporation today announced the U.S. and European launches of the Neuroform EZ™ Stent System, its fourth-generation intracranial aneurysm stent system designed for use in conjunction with endovascular coiling to treat wide-necked aneurysms. The Company plans to launch the product immediately in both markets.

26 Jul 2010

Vical's prophylactic Vaxfectin-formulated pDNA vaccine effective against HSV-2 in animal model

Vical Incorporated today announced that its prophylactic Vaxfectin®-formulated plasmid DNA (pDNA) vaccine against herpes simplex virus type 2 (HSV-2) protected mice against lethal challenge, provided sterilizing immunity and inhibited viral counts at both the primary and latent infection sites. The Vaxfectin® adjuvant substantially improved vaccine effectiveness. A related vaccine significantly reduced the recurrence of HSV-2 lesions in a therapeutic model using guinea pigs with latent infection.

26 Jul 2010

Medtronic glucose monitoring device helps owners manage pets’ diabetes

The treatment of diabetes was revolutionized in 1922 when insulin was isolated from dogs. Since then, significant advances in human medicine have made diabetes more manageable for patients. Now, human medicine has returned the favor and used these advances to help dogs with diabetes. A University of Missouri researcher is using a continuous glucose monitoring device - commonly used in humans with diabetes - to help treat dogs and other animals. The device, which provides a detailed glucose picture of an animal over several days, will help pet owners manage their pets' diabetes.

26 Jul 2010

Radiologists better at evaluating legal cases: Study

A study by University of North Carolina at Chapel Hill researchers found that 31 radiologists who reviewed the CT scans used in a medical malpractice lawsuit did not agree with the conclusions reached by four paid medical expert witnesses in the case.

26 Jul 2010

Kindergarten puppet show reduces anxiety of kids with cancer

THE PUPPET SHOW IS PART OF THE BACK-TO-SCHOOL PROGRAM AT DANA-FARBER CANCER INSTITUTE IN BOSTON. IT'S DESIGNED TO REDUCE THE ANXIETY OF CHILDREN LIVING WITH CANCER. LISA SCHERBER (SHER-BURR) HEAD'S UP THE PROGRAM.

26 Jul 2010

Axela acquires Xceed Molecular

Axela Inc., an innovator in systems that multiplex protein biomarker testing in clinical research and diagnostics, has acquired Xceed Molecular, developer of the award-winning Ziplex® System for gene-expression analysis, the Breast Cancer Prognostic Assay, and Colon Cancer Xpress chip. The new Axela will be introduced at the 2010 American Association of Clinical Chemistry (AACC) annual meeting and Clinical Lab Expo, which takes place July 25 – 29 at the Anaheim Convention Center in California.

26 Jul 2010

Study compares current state of healthcare system in UK and proposed system in US

A comparison of the current state of the healthcare system in the UK and the new system proposed under legislation pushed through by Barack Obama's government, shows some surprising results. The review is published in the Journal of the Royal Society of Medicine (JRSM).

26 Jul 2010

Nano-patch to replace needles for vaccination soon: Study

Those who fear needles have good news awaiting them. Australian researchers have developed a new method of vaccine delivery using needle-free nano-patches. These could also be mailed to people during pandemics. This breakthrough is published in the latest edition of the journal Small.

26 Jul 2010

Boehringer Ingelheim announces European CHMP Positive Opinion for TWYNSTA

Boehringer Ingelheim announced today that the European Committee for Medicinal Products for Human Use (CHMP) adopted a Positive Opinion for the approval of TWYNSTA®. It will be indicated in adults whose blood pressure is not adequately controlled on amlodipine and is also indicated as replacement therapy in adult patients receiving telmisartan and amlodipine from separate tablets can instead receive tablets of TWYNSTA containing the same component doses.

26 Jul 2010

Highlights on reasoning behind MRC's negative decision on funding of IVF

Thirty-two years ago today, the world's first baby was born after in vitro fertilisation. However, the work that led to the birth of Louise Brown on 25 July 1978 had to be privately funded after the UK's Medical Research Council decided in 1971 against providing the Cambridge physiologist Robert Edwards and the Oldham gynaecologist Patrick Steptoe with long-term financial support. Today, an intriguing paper published in Europe's leading reproductive medicine journal Human Reproduction reveals for the first time the reasoning behind the MRC's much-criticised decision.

26 Jul 2010

Researchers recommend six steps for shared decision making in sex development disorder surgery

A shared decision-making process would assist doctors and parents who are facing the extraordinarily complex, challenging and controversial choices presented when infants are born with genetic or anatomical anomalies in sexual development and are being considered for elective corrective surgery, a new research paper suggests.

26 Jul 2010

North Shore-LIJ Health System seeks oropharynx patients for phase I clinical trial

The North Shore-LIJ Health System Department of Radiation Medicine announced today it is seeking patients with cancer of the oropharynx (back of the mouth) to participate in a Phase I clinical trial.Subjects must be newly diagnosed and not have undergone any previous treatment. Further, their cancer must be unassociated with the human papilloma virus (HPV-negative), or, if it is HPV-positive, they must be current or former pack-a-day smokers for at least 10 years.

26 Jul 2010

Scientists develop nanoprobe to detect blood vessel growth in tumors

Formation of new blood vessels, also known as angiogenesis, is crucial for sustained tumor growth and cancer metastasis. Recently, clinically available therapies to suppress the growth of these vessels have been available to improve patient survival in some cancer types. Accurate detection and quantification of blood vessel growth using nonsurgical methods would greatly complement current therapies and allow physicians to quickly assess treatment regimens and adjust them as necessary. In the work published in the August issue of Experimental Biology and Medicine, Kessinger and coworkers have incorporated nanotechnology, material science, and the clinical imaging modality MRI, to create a nanosized probe capable of noninvasively visualizing and quantifying the blood vessel growth in tumors in a preclinical model.

26 Jul 2010

Neu5Gc in drugs provokes strong immune response

Researchers at the University of California, San Diego School of Medicine have discovered that a kind of sugar molecule common to chimpanzees, gorillas and other mammals but not found in humans provokes a strong immune response in some people, likely worsening conditions in which chronic inflammation is a major issue.

26 Jul 2010

Pulse Report 2010: Recession, unemployment, insurance losses increase pressure on ERs, patients

Average length of stay in the nation's emergency departments increased to four hours and seven minutes, and the nation's emergency physicians are very concerned about patient safety being jeopardized by long wait times. Press Ganey's Pulse Report 2010, released yesterday, confirms what the American College of Emergency Physicians has reported previously: The recession, high unemployment and insurance losses are increasing pressure on emergency departments and their patients.

26 Jul 2010

Research roundup: Hospital emergency room HIV screenings; Medical device reviews; Health law impact on docs and hospitals

Physician Satisfaction With Chronic Care Processes: A Cluster-Randomized Trial Of Guided Care - The authors randomly assigned teams of physicians and their chronically ill older patients into groups that either provided Guided Care - an educated registered nurse works with a primary care practice team to enhance quality of care - or usual care. One year later, they measured "physicians' satisfaction with chronic care processes, time spent on chronic care, knowledge of their chronically ill older patients, and care coordination provided by physicians and office staff."

26 Jul 2010

Diagnostic guidelines for arthritis-related back pain result in excessive tests, delay in pain relief: Research

Slavishly following long-held guidelines for diagnosing the cause of arthritis-related back pain is resulting in excessive tests, delays in pain relief and wasteful spending of as much as $10,000 per patient, new Johns Hopkins-led research suggests.

26 Jul 2010

Medicine News and Research

Seaside Therapeutics reports positive data from STX209 Phase 2 study in fragile X syndrome

Brainlab launches ExacTrac Infrared Monitoring device for patient positioning during radiation therapy

Obesity linked to early puberty in girls

Boston Scientific launches Neuroform EZ Stent System

Vical's prophylactic Vaxfectin-formulated pDNA vaccine effective against HSV-2 in animal model

Medtronic glucose monitoring device helps owners manage pets’ diabetes

Radiologists better at evaluating legal cases: Study

Kindergarten puppet show reduces anxiety of kids with cancer

Axela acquires Xceed Molecular

Study compares current state of healthcare system in UK and proposed system in US

Nano-patch to replace needles for vaccination soon: Study

Boehringer Ingelheim announces European CHMP Positive Opinion for TWYNSTA

Highlights on reasoning behind MRC's negative decision on funding of IVF

Researchers recommend six steps for shared decision making in sex development disorder surgery

North Shore-LIJ Health System seeks oropharynx patients for phase I clinical trial

Scientists develop nanoprobe to detect blood vessel growth in tumors

Neu5Gc in drugs provokes strong immune response

Pulse Report 2010: Recession, unemployment, insurance losses increase pressure on ERs, patients

Research roundup: Hospital emergency room HIV screenings; Medical device reviews; Health law impact on docs and hospitals

Diagnostic guidelines for arthritis-related back pain result in excessive tests, delay in pain relief: Research

Everything there is to know about biosimilars eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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