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New computational model could forecast cholera outbreaks

Just as the rainy season is driving a new surge of cholera cases in Haiti, a new computational model could forecast where outbreaks are likely to occur.

11 Aug 2011

Researchers identify novel sensory pathway that modulates pro-inflammatory cells

New research led by Derya Unutmaz, MD associate professor, the Departments of Pathology, Medicine, and Microbiology at NYU School of Medicine and Mark Sundrud, PhD, of Tempero Pharmaceuticals, Inc., has identified a novel sensory pathway that modulates the potency of Th17 cell responses.

11 Aug 2011

Erythromycin can prevent and treat aseptic loosening of total joint replacement

Total joint replacement surgeries can help relieve joint pain common in people with conditions like osteoarthritis. But sometimes, the debris from prosthetic joints leads to aseptic loosening, or disintegration of surrounding bones.

10 Aug 2011

Vitamin D, UVB may help prevent dental caries

Large geographical variations in dental health and tooth loss among U.S. adolescents and young adults have been reported since the mid-1800s. The first study finding a north-south gradient in dental caries was a report of men rejected from the draft for the Civil War for lost teeth, from 8 per 1000 men in Kentucky to 25 in New England.

10 Aug 2011

Moderate exercise may help prevent cognitive decline after bacterial infection

A small amount of exercise shields older animals from memory loss following a bacterial infection, according to a study in the August 10 issue of The Journal of Neuroscience.

10 Aug 2011

Scientists identify small molecule inhibitors of cellular uptake

Scientists from Freie Universität Berlin and the NeuroCure Cluster of Excellence led by biochemist Volker Haucke in collaboration with colleagues from Australia and the Leibniz Institute for Molecular Pharmacology in Berlin have developed small molecules that inhibit the internalization of important signaling molecules but also of pathogenic organisms such as the immunodeficiency virus and bacteria into cells.

5 Aug 2011

News media registration now open for ASM annual infectious diseases meeting

News media registration for the annual infectious diseases meeting of the American Society for Microbiology (ASM) is now open.

5 Aug 2011

Entomologist to study how immune system responds to rickettsial infection

Summer for most people means time spent outdoors, which could also mean increased exposure to bugs and, possibly, arthropod-borne diseases, such as "rickettsial diseases" - infectious diseases spread by bacteria, which, generally, are transmitted by lice, fleas, ticks and mites.

5 Aug 2011

New legislation allows physicians in Texas to treat chronic Lyme disease

Summertime, when kids and grown-ups abandon the confines of the indoors and head outside to camp, hike, fish and commune with nature -- and all of her friends. Flies, mosquitoes and ticks are just a few of the critters that go along with summer outdoors, and we all do our best to avoid the biting and stinging insects, but what happens if you are accosted by a tick? What are the myths behind Lyme disease and other tick-borne diseases in Texas?.

5 Aug 2011

UTHealth student receives UNCF/Merck fellowship for multidrug-resistant CDI research

Charles Darkoh, a graduate student at The University of Texas Health Science Center at Houston (UTHealth), has been awarded a fellowship from the United Negro College Fund (UNCF) and Merck for his research into a major health problem - multidrug-resistant Clostridium difficile bacterial infection.

3 Aug 2011

Researchers sample hydrogenotrophic microbes in the healthy human colon

They make up less than one-hundredth of 1 percent of the microbes that live in the colon, but the bacteria and archaea that sop up hydrogen in the gut are fundamental to colon health. In a new study, researchers take a first look at these "hydrogenotrophic" microbes, mapping where they live and how abundant they are in different parts of the lower intestine.

3 Aug 2011

Cubist initiates CXA-201 Phase 3 trial in complicated urinary tract infections

Cubist Pharmaceuticals, Inc. today announced the initiation of a pivotal Phase 3 trial of CXA-201 in patients with complicated urinary tract infections.

1 Aug 2011

PathoGenetiX receives $4.0 million in first close of Series B financing

PathoGenetiX Inc., today announced that the Company has received $4.0 million in the first closing of its Series B financing.

1 Aug 2011

Sorrento receives NIAID Phase I STTR grant to develop vaccines against C. difficile infection

Sorrento Therapeutics, Inc. announced today that it has received a Phase I Small Business Technology Transfer Research grant from the National Institute of Allergy and Infectious Diseases of the National Institutes of Health.

29 Jul 2011

SMRT DNA sequencing technology reveals genetic profile of German E. coli bacteria

An international team of scientists has successfully employed single molecule, real-time DNA sequencing technology from Pacific Biosciences of California, Inc. to provide valuable insights into the pathogenicity and evolutionary origins of the highly virulent bacterium responsible for the German E. coli outbreak.

28 Jul 2011

University of Pittsburgh to honor Synthetic Genomics CEO with Dickson Prize

The scientist-entrepreneur who led efforts to map the first draft of the human genome as well as the complete diploid genome and to construct the first synthetic bacterium has been named this year's recipient of the University of Pittsburgh's Dickson Prize in Medicine.

28 Jul 2011

Carcinogenesis is just another form of speciation, proposes new theory

Cancer patients may view their tumors as parasites taking over their bodies, but this is more than a metaphor for Peter Duesberg, a molecular and cell biology professor at the University of California, Berkeley.

27 Jul 2011

New details about how dendritic cells regulate fate of naive T cells

St. Jude Children's Research Hospital scientists show that the molecule serves as a bridge between the two arms of the immune system that provides a new mechanism guiding T cell differentiation.

25 Jul 2011

Cholera hits Haiti again

Cholera the bacterial disease that rapidly leads to diarrhea and dehydration and kills millions worldwide ravaged Haiti last fall and has spread quickly to all regions of the Caribbean country. With the rainy season now in progress, clinics across the country are again bustling with seriously ill patients.

24 Jul 2011

Contaminated nasal spray associated with rare bacterial outbreak

Infection control researchers investigating a rare bacterial outbreak of Burholderia cepacia complex (Bcc) identified contaminated nasal spray as the root cause of the infections, leading to a national recall of the product.

22 Jul 2011