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Mendelian randomization not the 'Holy Grail' in evaluating alcohol intake with cognitive function

Many observational cohort studies have shown that moderate alcohol use is associated with better cognitive function. However, since such studies are vulnerable to residual confounding by other lifestyle and physiologic factors, the authors conducted a Mendelian randomization study, using aldehyde dehydrogenase 2 (ALDH2) genotype (AA, GA, or GG) as an instrumental variable in 2-stage least squares analysis.

23 Mar 2012

Hyperion acquires worldwide rights to Ucyclyd's Ravicti

Hyperion Therapeutics, Inc. today announced that it has acquired worldwide rights to the investigational drug Ravicti from Ucyclyd Pharma, Inc., a wholly owned subsidiary of Medicis Pharmaceutical Corporation.

23 Mar 2012

Drexel experts available to comment for news stories about autism

Experts at Drexel University are available to comment for news stories about autism for Autism Awareness Month in April. Drexel recently established the A.J. Drexel Autism Institute, the nation's first autism center focused on public health science.

22 Mar 2012

$Large geographic variation in risk of hip fracture$

Large geographic variation in risk of hip fracture

An extensive study of country-specific risk of hip fracture and 10-year probability of a major fragility fracture has revealed a remarkably large geographic variation in fracture risk. Even accounting for possible errors or limitations in the source data, there was an astonishing 10-fold variation in hip fracture risk and fracture probability between countries.

22 Mar 2012

Colorectal cancer screening rates higher in population with multiple morbidities

A study by University of Kentucky researchers showed that in Appalachia, colorectal cancer screening rates were higher in the population with multiple morbidities or diseases compared to those who had no morbidities at all.

21 Mar 2012

Drexel University to establish nation's first autism center

Drexel University has received a gift of $1.5 million from the Charles and Barbara Close Foundation, founded by Drexel alumnus Charles Close ('36), to help establish the A.J. Drexel Autism Institute.

21 Mar 2012

UAB to present at annual American College of Cardiology Scientific Sessions

The University of Alabama at Birmingham has a number of presentations and experts available to comment on news being presented at the annual American College of Cardiology Scientific Sessions that begin Saturday, March 23, 2012, in Chicago.

20 Mar 2012

Study identifies new hypervariable regions in human gut viruses

A growing body of evidence underscores the importance of human gut bacteria in modulating human health, metabolism, and disease. Yet bacteria are only part of the story. Viruses that infect those bacteria also shape who we are. Frederic D. Bushman, PhD, professor of Microbiology at the Perelman School of Medicine at the University of Pennsylvania, led a study published this month in the Proceedings of the National Academy of Sciences that sequenced the DNA of viruses -- the virome -- present in the gut of healthy people.

20 Mar 2012

Infection preventionists, healthcare epidemiologists play key roles in promoting antimicrobial stewardship

Infection preventionists and healthcare epidemiologists play key roles in promoting effective antimicrobial stewardship in collaboration with other health professionals, according to a joint position paper published today by the Association for Professionals in Infection Control and Epidemiology (APIC) and the Society for Healthcare Epidemiology of America (SHEA) in their respective peer-review journals, the American Journal of Infection Control and Infection Control and Hospital Epidemiology.

20 Mar 2012

Low literacy equals high death risk among elderly

A new study that appeared last Friday in British Medical Journal showed that one in three adults aged over 65 in England have difficulty understanding basic health-related information. They are more than twice as likely to die within five years as adults with no literacy problems, it was found.

19 Mar 2012

Obesity appears to increase risk of mortality tied to sleeping pills

Obesity appears to significantly increase the risk of death tied to sleeping pills, nearly doubling the rate of mortality even among those prescribed 18 or fewer pills in a year, researchers reported Friday.

17 Mar 2012

Older women with mild retinopathy more likely to have cognitive decline and related vascular changes

Women 65 or older who have even mild retinopathy, a disease of blood vessels in the retina, are more likely to have cognitive decline and related vascular changes in the brain, according to a multi-institutional study led by scientists at the University of California, San Francisco (UCSF).

16 Mar 2012

Epigenetic designer baby may prove to be a non-starter

Epigenetics is the new hip science. Time Magazine's front cover and article, 'Why your DNA isn't your Destiny' from January 2010 explains why. Its more explicit subtitle provided the hook - 'The new science of epigenetics reveals how the choices you make can change your genes - and those of your kids'. Who wouldn't be interested in this?

16 Mar 2012

EORTC, EASL publish first joint CPGs on management of hepatocellular carcinoma

The European Association for the Study of the Liver (EASL) and the European Organisation for Research and Treatment of Cancer (EORTC) today publish their first joint Clinical Practice Guidelines (CPGs) on the management of hepatocellular carcinoma.

16 Mar 2012

Panel of 10 serum protein biomarkers could help in lung cancer diagnosis

A panel of serum biomarkers could help predict the level of lung cancer risk in high-risk patients, offering doctors an option before proceeding with a biopsy. Research presented in the April 2012 issue of the International Association for the Study of Lung Cancer's (IASLC) Journal of Thoracic Oncology shows that a panel of 10 serum protein biomarkers could help in the lung cancer diagnosis.

16 Mar 2012

New evidence on the link between suicide and economy

New evidence on the link between suicide and the economy shows that the monthly suicide rate in New York City from 1990 to 2006 was 29% higher at the economic low point in 1992 than at the peak of economic growth in 2000.

16 Mar 2012

Patients with early stage MPM may be eligible for aggressive multi-modality therapy

Patients with early stage malignant pleural mesothelioma (MPM), a cancer that develops in the lining of the lungs, may be eligible for aggressive multi-modality therapy involving surgery, radiotherapy and chemotherapy.

16 Mar 2012

Scientists discover direct biomarker of Chikungunya fever

Recent breakthroughs in Chikungunya research spearheaded by scientists at A*STAR's Singapore Immunology Network (SIgN) have made great strides in the battle against the infectious disease.

15 Mar 2012

H. pylori bacteria associated with elevated levels of HbA1c

A new study by researchers at NYU Langone Medical Center reveals that the presence of Helicobacter pylori (H. pylori) bacteria is associated with elevated levels of glycosylated hemoglobin (HbA1c), an important biomarker for blood glucose levels and diabetes.

15 Mar 2012

New study suggests another benefit to antimicrobial stewardship

Curbing unnecessary use of antibiotics is our best defense against the spread of drug-resistant infections. A new study suggests another benefit to antimicrobial stewardship: a potential cost savings of millions of dollars now wasted on therapies that don't help patients.

15 Mar 2012