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UC San Diego Health first to offer new injectable medication to patients with hereditary transthyretin amyloidosis

UC San Diego Health is first in the nation to offer a new injectable medication to patients with nerve damage caused by hereditary transthyretin amyloidosis, a rare disease that can be fatal without management.

18 Aug 2022

GPNMB established as a risk gene and potential therapeutic target for Parkinson's disease

Computational, cell biological, and human tissue-based studies establish GPNMB as a risk gene and potential therapeutic target for Parkinson's Disease (PD), researchers report.

18 Aug 2022

Researchers visualize antigen-bound T-cell receptor at atomic resolution

T cells are our immune system’s customized tools for fighting infectious diseases and tumor cells. On their surface, these special white blood cells carry a receptor that recognizes antigens.

18 Aug 2022

Key gene sheds light on how people develop tolerance to pain-relievers over time

UF Scripps Biomedical Research scientists have a discovered a key gene that is shedding light on how people develop tolerance to pain-relievers over time, a problem that raises risk of addiction and overdose.

18 Aug 2022

Therapeutic target for several metabolic diseases may help fight Alzheimer’s disease

In the recent popular Korean TV series "The Light in Your Eyes," many viewers emphasized with the main character suffering from Alzheimer's disease.

18 Aug 2022

Researchers assess lutein nanodisks against ultraviolet light-induced retinal damage

Researchers assessed the role of lutein nanodisks against ultraviolet (UV) light-induced damage to retinal cells.

18 Aug 2022

Host anti-viral factors and pathways regulating SARS-CoV-2 infection

In a new study, researchers identified host anti-viral factors and pathways regulating SARS-CoV-2 infection.

18 Aug 2022

Researchers develop a novel method to screen publicly available raw WGS data of SARS-CoV-2

Researchers developed a novel method to screen publically available raw whole genome sequencing data of SARS-CoV-2 and identify mutations of interest more rapidly.

18 Aug 2022

Waning of humoral immune responses to SARS-CoV-2 after 14 months of infection

Researchers assessed humoral immune responses to and neutralization of the SARS-CoV-2 Delta (B.1.617.2) variant of concern after two months (T1) and 14 months (T2) of asymptomatic or mild wild-type (WT) SARS-CoV-2 infections.

18 Aug 2022

CD98 identified as a key mediator of pro-fibrotic and acute inflammatory responses in the lung

Researchers investigated the role of the CD98 glycoprotein in inducing an inflammatory response to SARS-CoV-2 in patients of progressive fibrosis interstitial lung diseases, including the archetypal PFILD, idiopathic pulmonary fibrosis.

18 Aug 2022

New strategies to enhance the survival of children with neuroblastoma

Neuroblastoma, a childhood cancer that develops from neural cells on the adrenal glands, accounts for 15% of childhood cancer deaths. Almost half of children with high-risk neuroblastoma harbor extra copies of the gene MYCN (MYCN amplified), the primary driver of neuroblastoma and its resistance to therapy.

18 Aug 2022

Eating disorders could be treated by modulating gut microbiota

Researchers describe how the gut-brain axis facilitates communication between the gastrointestinal tract and brain to regulate food consumption behaviors.

17 Aug 2022

Eating grapes may reduce the risk of fatty liver disease

In a recent study published in the journal Foods, eating grapes can extend life expectancy by five years and reduce non-alcoholic fatty liver disease risk in mice fed high-fat diets.

17 Aug 2022

$Elevated blood levels of certain chemokine linked with higher hip fracture risk in men$

Elevated blood levels of certain chemokine linked with higher hip fracture risk in men

Bone health requires a balanced activity of various bone cell types including bone-forming osteoblasts and bone-resorbing osteoclasts.

17 Aug 2022

New method helps identify which gut microbes most likely contribute to inflammatory diseases

Cedars-Sinai investigators have developed a method to help identify which human gut microbes are most likely to contribute to a slew of inflammatory diseases like obesity, liver disease, inflammatory bowel disease, cancer and some neurological diseases.

17 Aug 2022

Researchers create novel mouse model for mapping protein communication between organs

Our many different organ systems are in constant communication with each other. During exercise, for example, muscles send out signals to fat and liver tissue to release their energy sources.

17 Aug 2022

Research suggests a new model of how beige fat biogenesis is controlled

Once considered an inert tissue, fat – or adipose tissue – is now known to play an active role in the body's critical functions by secreting hormones that regulate hunger and body temperature.

17 Aug 2022

Study contributes to better understanding of the changes in kinase activity in renal cell carcinoma

A new research paper was published in Oncotarget on August 4, 2022, entitled, "Kinase activity profiling in renal cell carcinoma, benign renal tissue and in response to four different tyrosine kinase inhibitors."

17 Aug 2022

Innovative technology revels the impact of environmental conditions on RNA structures in living cells

The impact of environmental conditions on the dynamic structures of RNAs in living cells has been revealed by innovative technology developed by researchers at the John Innes Centre.

17 Aug 2022

New anti-cancer drug candidate is absorbed through the lymphatic system rather than blood vessels

A team of University of Michigan researchers is developing a new anti-cancer drug that is absorbed through the gut's lymphatic system rather than blood vessels, potentially outmaneuvering the molecular signaling pathways that lead to drug resistance while increasing cancer-fighting ability and reducing side effects.

17 Aug 2022

Protein C News and Research

UC San Diego Health first to offer new injectable medication to patients with hereditary transthyretin amyloidosis

GPNMB established as a risk gene and potential therapeutic target for Parkinson's disease

Researchers visualize antigen-bound T-cell receptor at atomic resolution

Key gene sheds light on how people develop tolerance to pain-relievers over time

Therapeutic target for several metabolic diseases may help fight Alzheimer’s disease

Researchers assess lutein nanodisks against ultraviolet light-induced retinal damage

Host anti-viral factors and pathways regulating SARS-CoV-2 infection

Researchers develop a novel method to screen publicly available raw WGS data of SARS-CoV-2

Waning of humoral immune responses to SARS-CoV-2 after 14 months of infection

CD98 identified as a key mediator of pro-fibrotic and acute inflammatory responses in the lung

New strategies to enhance the survival of children with neuroblastoma

Eating disorders could be treated by modulating gut microbiota

Eating grapes may reduce the risk of fatty liver disease

Elevated blood levels of certain chemokine linked with higher hip fracture risk in men

New method helps identify which gut microbes most likely contribute to inflammatory diseases

Researchers create novel mouse model for mapping protein communication between organs

Research suggests a new model of how beige fat biogenesis is controlled

Study contributes to better understanding of the changes in kinase activity in renal cell carcinoma

Innovative technology revels the impact of environmental conditions on RNA structures in living cells

New anti-cancer drug candidate is absorbed through the lymphatic system rather than blood vessels

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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