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COVID-19 epidemic is the product of natural evolution, study finds

The novel SARS-CoV-2 coronavirus that emerged in the city of Wuhan, China, last year and has since caused a large scale COVID-19 epidemic and spread to more than 70 other countries is the product of natural evolution, according to findings published today in the journal Nature Medicine.

17 Mar 2020

New understanding of signaling molecule interleukin-2 can guide drug discovery efforts

The signaling molecule interleukin-2 (IL-2) has long been known to have powerful effects on the immune system, but efforts to harness it for therapeutic purposes have been hampered by serious side effects.

17 Mar 2020

Cannabinoid 1 receptor expression displays sexually dimorphic pattern in the mouse brain

A major challenge in neuroscience lies in understanding how molecular and circuit differences in the brain synergistically contribute to sex differences in behavioral phenotypes. Sex differences in the brain may arise from the identity, distribution and relative abundance of cell types.

17 Mar 2020

Max Planck researchers identify mechanistic basis of antigen receptor gene assembly

Adaptive immunity is a powerful defense mechanism in vertebrates. A finely tuned interplay of different cell types provides a pathogen-specific immune response to eliminate for example bacteria and viruses.

13 Mar 2020

Study shows JNK protein as a stress sensor in synapses

New study from Eleanor Coffey's lab at Turku Bioscience Centre in Finland identifies that the JNK protein triggers nerve cells to withdraw their synapses when stressed.

11 Mar 2020

Novel strategy to stop tumors from developing new blood vessels

Scientists at the National Institutes of Health and other institutions have devised a new strategy to stop tumors from developing the new blood vessels they need to grow.

11 Mar 2020

New approach to stimulate immune cells may provide better protection against Alzheimer's

Scientists at the German Center for Neurodegenerative Diseases, the Ludwig-Maximilians-Universitaet Munich and Denali Therapeutics (South San Francisco, CA, USA) have developed an approach to stimulate immune cells of the brain in such a way that they might possibly provide better protection against Alzheimer's disease.

10 Mar 2020

Immune systems of preemies can catch up

According to a new study published in March 2020 in the journal Nature Communications, babies born prematurely up to 32 weeks of pregnancy can quickly catch up on their immune system function after birth, bringing them to a state comparable to term infants.

9 Mar 2020

Investigational CAR-T therapy for Hodgkin lymphoma receives fast-track designation from FDA

Based on proof-of-concept results from clinical trials at University of North Carolina Lineberger Comprehensive Cancer Center and Baylor College of Medicine, an investigational cellular immunotherapy for Hodgkin lymphoma has received a Regenerative Medicine Advanced Therapy designation from the U.S. Food and Drug Administration.

9 Mar 2020

Scientists may have found a way to prevent coronavirus spread

Just like any other virus, the coronavirus needs a host to survive. Viruses enter the cells of the human body to cause disease by attaching to a specific receptor site on the host cell membrane. To do this, they attach to proteins in the capsid through glycoproteins found in the envelope of the virus.

8 Mar 2020

The Pancreatic Cancer Collective awards additional funding of $16 million for new therapies

The Pancreatic Cancer Collective, the strategic partnership of Lustgarten Foundation and Stand Up To Cancer, has awarded additional funding of up to $16 million to four teams of top researchers as part of its "New Therapies Challenge Grants," the American Association for Cancer Research, Scientific Partner of SU2C, announced today.

5 Mar 2020

Study provides new insight into neurofibromin-deficient ER+ breast cancer

An international team of researchers led by scientists at Baylor College of Medicine has new insights into the function of neurofibromin, a tumor suppressor produced by the NF1 gene.

5 Mar 2020

Researchers find previously unknown response within gut microbiome

The gut microbiome, which is a collection of numerous beneficial bacteria species, is key to our overall well-being and good health. Recent studies have linked the gut microbiome with several beneficial properties, such as aiding in the development of our immune system and warding off pathogen infections.

5 Mar 2020

Coronavirus is mutating with a second strain identified by scientists

The coronavirus is mutating as scientists identified a second strain, which is more aggressive and contagious.

5 Mar 2020

Researchers identify a gut microbe generated byproduct linked to cardiovascular disease

Cleveland Clinic researchers have identified a gut microbe generated byproduct - phenylacetylglutamine - that is linked to development of cardiovascular disease, including heart attack, stroke and death.

5 Mar 2020

Researchers uncover novel neurotransmitter system in the brain

Neurotransmitters are chemicals that transmit signals between neurons or from neurons to other cells. They interact with specific receptors found in the brain of humans and animals, controlling a variety of biological processes, e.g. fear, anger, pleasure, memory, energy, appetite and sleep.

5 Mar 2020

Fatty nutrients control certain neurons in the reward circuit

Energy-dense food, obesity and compulsive food intake bordering addiction: the scientific literature has been pointing to connections between these for years.

5 Mar 2020

Study provides new evidence about optimal way to treat BRCA carriers with breast cancer

Commonly known as the breast cancer genes, the BRCA gene family plays a role in repairing damaged DNA. Inherited mutations in the genes BRCA1 or BRCA2 raise the risk of developing breast, ovarian, prostate and other cancers.

5 Mar 2020

Researchers identify mechanism that explains why women experience more pain than men

Imagine taking a pill to control your pain and, instead, the medication actually increases the pain you feel.

5 Mar 2020

New technique helps study peptide-receptor interactions on the cell surface

In the past, biologically-active peptides - small proteins like neurotoxins and hormones that act on cell receptors to alter physiology - were purified from native sources like venoms and then panels of variants were produced in bacteria, or synthesized, to study the structural basis for receptor interaction.

5 Mar 2020

Receptor News and Research

COVID-19 epidemic is the product of natural evolution, study finds

New understanding of signaling molecule interleukin-2 can guide drug discovery efforts

Cannabinoid 1 receptor expression displays sexually dimorphic pattern in the mouse brain

Max Planck researchers identify mechanistic basis of antigen receptor gene assembly

Study shows JNK protein as a stress sensor in synapses

Novel strategy to stop tumors from developing new blood vessels

New approach to stimulate immune cells may provide better protection against Alzheimer's

Immune systems of preemies can catch up

Investigational CAR-T therapy for Hodgkin lymphoma receives fast-track designation from FDA

Scientists may have found a way to prevent coronavirus spread

The Pancreatic Cancer Collective awards additional funding of $16 million for new therapies

Study provides new insight into neurofibromin-deficient ER+ breast cancer

Researchers find previously unknown response within gut microbiome

Coronavirus is mutating with a second strain identified by scientists

Researchers identify a gut microbe generated byproduct linked to cardiovascular disease

Researchers uncover novel neurotransmitter system in the brain

Fatty nutrients control certain neurons in the reward circuit

Study provides new evidence about optimal way to treat BRCA carriers with breast cancer

Researchers identify mechanism that explains why women experience more pain than men

New technique helps study peptide-receptor interactions on the cell surface

Industry Focus eBook - Forensics & toxicology (2nd edition) eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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