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New clues for an effective AIDS vaccine

Two simple changes in its outer envelope protein could render the AIDS virus vulnerable to attack by the immune system, according to research from Kenya and the Fred Hutchinson Cancer Research Center published in PLoS Medicine.

4 Jan 2008

Gene therapy can reduce long-term drinking among rodents

Just as the risk of developing alcoholism is strongly influenced by genetic factors, mutations in gene coding - such as the aldehyde dehydrogenase (ALDH2*2) allele - also appear to protect against the risk.

4 Jan 2008

Down syndrome points to a new way of repressing cancer growth

Researchers at Johns Hopkins and Ohio State University have found that the number of copies of a particular gene can affect the severity of colon cancer in a mouse model. Publishing in the Jan. 3 issue of Nature, the research team describes how trisomy 21, or Down syndrome in humans, can repress tumor growth.

4 Jan 2008

Big pharma spends almost twice as much on marketing drugs than on research and development

The pharmaceutical industry spends almost twice as much on the marketing and promotion of drugs than on research and development, according to a new analysis in this week's PLoS Medicine.

4 Jan 2008

Urinary tract infections from the catheter - most common hospital-acquired infection

One in four Americans in the hospital right now has a urinary catheter. One percent of them will get a urinary tract infection from that catheter.

4 Jan 2008

Experimental IT to reduce medication errors under study

Medication errors are one of the most serious problems occurring in doctor's offices and out-patient clinics, and older persons with chronic conditions are the most vulnerable.

4 Jan 2008

Polyphenols in wine may help prevent cavities

A class of chemicals in red wine grapes may significantly reduce the ability of bacteria to cause cavities, according to a study published recently in the Journal of Agricultural and Food Chemistry.

3 Jan 2008

Vitamin D2 is as effective as vitamin D3 in maintaining concentrations of 25-hydroxyvitamin D

Researchers from Boston University School of Medicine (BUSM) have found that vitamin D2 is equally as effective as vitamin D3 in maintaining 25-hydroxyvitamin D status.

3 Jan 2008

Effects of sleep deprivation reversed

Researchers at Wake Forest University School of Medicine have shown that the effects of sleep deprivation on cognitive performance can be reversed when the naturally occurring brain peptide, orexin-A, is administered in monkeys.

3 Jan 2008

New hope for Batten disease sufferers

Investigators at the University of Rochester Medical Center have uncovered a promising drug therapy that offers a ray of hope for children with Batten disease – a rare neurodegenerative disease that strikes seemingly healthy kids, progressively robs them of their abilities to see, reason and move, and ultimately kills them in their young twenties.

3 Jan 2008

New understanding of hydrogen peroxide's role in cell health

Hydrogen peroxide, the same mild acid that many people use to disinfectant their kitchens or treat cuts and abrasions, is also produced by the body to keep cells healthy.

3 Jan 2008

Protein's new role discovered in autoimmune disease

Investigators at the University of Alabama at Birmingham (UAB) have identified the previously unknown role of a chemical 'messenger' leading to autoimmune disorders like rheumatoid arthritis and lupus.

3 Jan 2008

Protein a possible key to allergy and asthma control

Activating a protein found on some immune cells seems to halt the cells' typical job of spewing out substances that launch allergic reactions, a study by Johns Hopkins researchers suggests.

3 Jan 2008

Avoiding overuse, misuse, and underuse of medications

Adverse drug events are more common in older adults because they are prescribed more drugs and are effected differently by these drugs than their younger counterparts.

3 Jan 2008

Bisphosphonates appear to reduce the risk of jaw degradation

Athanasios Zavras began receiving messages from distraught patients in 2005 after case reports linked oral osteoporosis meds to bone death in the jaw.

3 Jan 2008

Obese people less likely to use seatbelts

Obese people are less likely to use their seatbelts than the rest of the population, adding to the public health risks associated with this rapidly growing problem.

3 Jan 2008

Study to look at effect of high dose vitamin C on non-Hodgkin lymphoma patients

Scientists at Thomas Jefferson University Hospital and Jefferson's Kimmel Cancer Center have received approval for a first-of-its kind study on the effect high dose vitamin C has on non-Hodgkin lymphoma patients.

3 Jan 2008

For hospital patients, defibrillation delays mean lower survival

An estimated 750,000 hospitalized patients experience cardiac arrest and undergo CPR annually, and less than 30 percent of those leave the hospital alive.

3 Jan 2008

FDA approves Hi-Flex mobile bearing knee prostheses

Mitchell Sheinkop, M.D., will be the first in the U.S. to surgically implant the just-approved Nex Gen LPS-Flex mobile bearing knee on February 20, 2008 at the Neurologic and Orthopedic Hospital of Chicago.

3 Jan 2008

New clue found to the cause of Parkinson's disease

A glitch in the mechanism by which cells recycle damaged components may trigger Parkinson's disease, according to a study by scientists at the Albert Einstein College of Medicine of Yeshiva University.

3 Jan 2008