Protein C News and Research

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Researchers develop new method for studying age-related brain disorders

Researchers at Lund University in Sweden have developed a new method for studying age-related brain disorders.

17 Aug 2022

Study reveals a mechanism linking DDT exposure to Alzheimer's disease

A new study led by researchers from Florida International University (FIU) reveals a mechanism linking the pesticide DDT to Alzheimer's disease.

17 Aug 2022

Scientists elucidate the structure of Type IV secretion system involved in antibiotic resistance

With antibiotic-resistant bacteria on the rise, scientists have been searching for ways to shut down the Type IV secretion system (T4SS), a protein complex on the outer envelope of bacterial cells that helps them to exchange DNA with neighboring bacteria and resist antibiotics.

17 Aug 2022

Study identifies the link between a gene variant and protection against coronary atherosclerosis

The protective effect of the newly discovered variant against coronary heart disease is likely to be caused by the below-average arterial stiffness of variant carriers.

17 Aug 2022

Study provides insights into understanding the biology of circulating Hepatitis E variants

Over three million people are infected with the hepatitis E virus every year. So far, no effective treatment is available. An international team has investigated which factors are important for the virus in the course of its replication cycle and how it manages to maintain the infection.

17 Aug 2022

Novel AI algorithm predicts the risk of mortality for patients suffering a major injury

Scientists from the Department of Traumatology and Acute Critical Medicine at the Osaka University Graduate School of Medicine developed an AI algorithm to predict the risk of mortality for patients suffering a major injury. Using the Japan Trauma Data Bank for the years 2013 to 2017, they were able to obtain records for over 70,000 patients who had experienced blunt-force trauma, which allowed the researchers to identify critical factors that could guide treatment strategies more precisely.

17 Aug 2022

The neutralizing antibody escape of BA.2.75 in mRNA-vaccinated and BA.1-infected individuals

Investigators analyzed the neutralization escape of the SARS-CoV-2 Omicron BA.2.75 variant.

17 Aug 2022

The impact of the P681H spike mutation in the SARS-CoV-2 Alpha variant

Researchers demonstrated the relevance of the P681H spike mutation in the SARS-CoV-2 Alpha variant.

17 Aug 2022

$Chemokines likely to be associated with the risk of osteoporotic hip fracture in older men$

Chemokines likely to be associated with the risk of osteoporotic hip fracture in older men

Bone health requires a balanced activity of various bone cell types including bone-forming osteoblasts and bone-resorbing osteoclasts. Osteoporosis occurs when osteoclasts dominate without adequate bone formation to compensate. In new research published in the Journal of Bone and Mineral Research, elevated blood levels of a certain chemokine, or small signaling protein, that promotes osteoclast formation were linked with a higher risk of hip fracture in men.

17 Aug 2022

UC San Diego receives $1.3 million grant to understand the role of misfolded tau proteins in dementia

Researchers at the University of California San Diego have received a $1.3 million grant from the W. M. Keck Foundation for a project that could help scientists better understand the role misfolded tau proteins play in causing neurodegenerative diseases like dementia, which may lead to more effective drug therapies.

16 Aug 2022

SARS-CoV-2 evolution within hosts and vaccination effects

A new study explores the mutational profiles within individuals infected with SARS-CoV-2.

16 Aug 2022

Discovery explains how impaired metabolism triggers neuroendocrine tumors in the adrenal glands

Researchers have deciphered a signaling cascade through which inborn errors in metabolism provoke deadly neuroendocrine tumors in the adrenal glands.

16 Aug 2022

Non-invasive biomarker could aid with earlier diagnosis of breast cancer metastasis

One woman is diagnosed with breast cancer every fourteen seconds somewhere across the globe - based on data showing that an approximate 2.3 million women worldwide were newly diagnosed with breast cancer in 2020.

16 Aug 2022

UT Southwestern's cryo-EM images shed light on the mechanisms behind Wnt signaling activation

Using UT Southwestern's Cryo-Electron Microscopy Facility, researchers have captured images of an enzyme for Wnt lipidation, which is pivotal to human development and cancer and crucial for Wnt signaling activation.

16 Aug 2022

Impact of SARS-CoV-2 Omicron subvariant breakthrough infections on memory responses

Researchers examined antibodies (Abs) generated by memory B cells (MBCs) after three and four SARS-CoV-2 exposures by infections with SARS-CoV-2 Delta and Omicron BA.1 variants, respectively.

16 Aug 2022

Novel peptide helps prevent seizures, protects neurons in research models of both Alzheimer's and epilepsy

A novel peptide augments the brain's natural mechanism to help prevent seizures and protect neurons in research models of both Alzheimer's and epilepsy, scientists report.

16 Aug 2022

Study uncovers a key role for MKK3/6–p38γ/δ signaling pathway in cardiac hypertrophy

A study carried out by scientists at the Centro Nacional de Investigaciones Cardiovasculares (CNIC) and led by Dr. Guadalupe Sabio has identified a key role for the MKK3/6–p38γ/δ signaling pathway in the development of cardiac hypertrophy.

16 Aug 2022

What is the potential role of sphingosine kinase inhibitors as antiviral agents?

In a new study, researchers explored sphingosine kinases inhibitors and characterized the role of SKs in Ebola virus (EBOV) entry.

16 Aug 2022

The validity of saliva samples after long-term storage for detection of SARS-CoV-2

Researchers investigated if storage time could affect the reliability of human salivary samples for detection of SARS-CoV-2.

16 Aug 2022

What drugs can be repurposed for monkeypox therapy?

In new research, researchers repurposed medications for the monkeypox virus in silico.

16 Aug 2022

Protein C News and Research

Researchers develop new method for studying age-related brain disorders

Study reveals a mechanism linking DDT exposure to Alzheimer's disease

Scientists elucidate the structure of Type IV secretion system involved in antibiotic resistance

Study identifies the link between a gene variant and protection against coronary atherosclerosis

Study provides insights into understanding the biology of circulating Hepatitis E variants

Novel AI algorithm predicts the risk of mortality for patients suffering a major injury

The neutralizing antibody escape of BA.2.75 in mRNA-vaccinated and BA.1-infected individuals

The impact of the P681H spike mutation in the SARS-CoV-2 Alpha variant

Chemokines likely to be associated with the risk of osteoporotic hip fracture in older men

UC San Diego receives $1.3 million grant to understand the role of misfolded tau proteins in dementia

SARS-CoV-2 evolution within hosts and vaccination effects

Discovery explains how impaired metabolism triggers neuroendocrine tumors in the adrenal glands

Non-invasive biomarker could aid with earlier diagnosis of breast cancer metastasis

UT Southwestern's cryo-EM images shed light on the mechanisms behind Wnt signaling activation

Impact of SARS-CoV-2 Omicron subvariant breakthrough infections on memory responses

Novel peptide helps prevent seizures, protects neurons in research models of both Alzheimer's and epilepsy

Study uncovers a key role for MKK3/6–p38γ/δ signaling pathway in cardiac hypertrophy

What is the potential role of sphingosine kinase inhibitors as antiviral agents?

The validity of saliva samples after long-term storage for detection of SARS-CoV-2

What drugs can be repurposed for monkeypox therapy?

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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