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Yale discovery has implications for treatment of diabetes and non-alcoholic fatty liver disease

Many health problems in the developed world stem from the disruption of a delicate metabolic balance between glucose production and energy utilization in the liver.

4 Mar 2020

Antidepressant shows promise in helping men with recurrent prostate cancer

An antidepressant in use for decades, repurposed to fight prostate cancer, shows promise in helping patients whose disease has returned following surgery or radiation, a pilot study at USC shows.

4 Mar 2020

Preclinical data of Ocugen's OCU400 genetic modifier published in Nature Gene Therapy

Ocugen, Inc., a clinical-stage company focused on discovering, developing and commercializing transformative therapies to treat rare and underserved ophthalmic diseases, announced today the publication in Nature Gene Therapy of preclinical data of nuclear hormone receptor gene NR2E3 as a genetic modifier and therapeutic agent to treat multiple retinal degenerative diseases.

3 Mar 2020

Inhibiting energy production in immune T-cells allows some tumors to escape treatment

A small molecule that inhibits energy production in immune T-cells allows some tumors to escape treatment with an immunotherapy called PD-1 blockade therapy, says a study in mice published today in eLife.

3 Mar 2020

New step towards the development of non-addictive painkillers

Opioid-containing painkillers are virtually indispensable in clinical practice and are typically used in postoperative patients and patients undergoing cancer treatment.

3 Mar 2020

Blocking immune T-cell regulator may help boost tumor killing, study shows

Immune system T-cells are more able to destroy skin cancer cells when a T-cell regulator called SLAMF6 is missing, a new study in eLife shows.

3 Mar 2020

Visceral fat gives signal to the brain that damages cognition

Excessive weight around our middle gives our brain's resident immune cells heavy exposure to a signal that turns them against us, setting in motion a crescendo of inflammation that damages cognition, scientists say.

3 Mar 2020

A protein critical for wound healing and neural repair following spinal cord injury identified

Plexin-B2, an axon guidance protein in the central nervous system (CNS), plays an important role in wound healing and neural repair following spinal cord injury (SCI), according to research conducted at the Icahn School of Medicine at Mount Sinai and published today in Nature Neuroscience. T

2 Mar 2020

The changing face of the COVID-19 epidemic

The SARS-CoV-2 (severe acute respiratory syndrome coronavirus 2) virus, which hit China with the disease now named COVID-19 in December 2019 and has since spread to over 70 countries, has caused over 90,000 cases, and 3,117 fatalities, with 95% or more of both being in China.

2 Mar 2020

Experimental drug offers hope for improving movement symptoms of Parkinson's

Results from a study looking at an experimental drug to tackle the debilitating side effect of dyskinesia, have offered hope that it may have potential as a future treatment for people with Parkinson's.

2 Mar 2020

Research reveals key role of a protein in rare Batten disease

Professor Stéphane Lefrançois, a researcher at the Institut National de la Recherche Scientifique (INRS), is working on Batten disease, a neurodegenerative genetic disease that primarily affects children. His research focuses on the most common form of the disease - Batten CLN 3 - which is caused by mutations in the protein of the same name and for which there is still no cure.

28 Feb 2020

Study shows how habits can be controlled based on the activity of the brain region

Each day, humans and animals rely on habits to complete routine tasks such as eating and sleeping. As new habits are formed, this enables us to do things automatically without thinking.

28 Feb 2020

Certain drugs can reduce epilepsy risk following traumatic brain injury

A research team led by a scientist at the University of California, Riverside, has found that brains treated with certain drugs within a few days of an injury have a dramatically reduced risk of developing epilepsy later in life.

28 Feb 2020

APEIRON Biologics launches clinical trial of respiratory drug to treat coronavirus infection

APEIRON Biologics AG, a biotechnology company with an approved product on the market as well as a broad preclinical and clinical pipeline, today announced the launch of a Pilot investigator-initiated clinical trial with APN01, a recombinant human angiotensin-converting enzyme 2, to treat patients with severe coronavirus infection in the People's Republic of China.

26 Feb 2020

Menopause age not associated with heart disease finds study

There has been conflicting evidence regarding early menopause and an increased risk for heart disease among women. This connection has been attributed to the lowering of female hormone estrogen levels in the blood.

26 Feb 2020

Chronic cough could be eased with new drug

A pair of studies have shown that chronic cough and its distressing symptoms could be eased with the help of a new drug. Also, the drug does not have side effects that can restrict its use, explain the researchers. The results of the two studies are published in The Lancet Respiratory Medicine, and the European Respiratory Journal, respectively.

26 Feb 2020

Receptor News and Research

Yale discovery has implications for treatment of diabetes and non-alcoholic fatty liver disease

Antidepressant shows promise in helping men with recurrent prostate cancer

Preclinical data of Ocugen's OCU400 genetic modifier published in Nature Gene Therapy

Inhibiting energy production in immune T-cells allows some tumors to escape treatment

New step towards the development of non-addictive painkillers

Blocking immune T-cell regulator may help boost tumor killing, study shows

Visceral fat gives signal to the brain that damages cognition

A protein critical for wound healing and neural repair following spinal cord injury identified

The changing face of the COVID-19 epidemic

Experimental drug offers hope for improving movement symptoms of Parkinson's

Research reveals key role of a protein in rare Batten disease

Study shows how habits can be controlled based on the activity of the brain region

Certain drugs can reduce epilepsy risk following traumatic brain injury

APEIRON Biologics launches clinical trial of respiratory drug to treat coronavirus infection

Menopause age not associated with heart disease finds study

Chronic cough could be eased with new drug

Cellular metabolism plays key role in dictating the fate decision between pathogenic and regulatory T cells

Aggressive cancers set up a structural framework to keep the immune system at bay

Scientists discover new biological mechanism of insulin signaling

Researchers reveal new details about how joint inflammation evolves in rheumatoid arthritis

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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