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New approach of screening drugs that encourage stem cells to repair damaged tissue

Professor Fiona Watt will today (12 July) give the Anne McLaren Memorial Lecture at the UK National Stem Cell Network annual science meeting and will detail a new approach to screening for drugs that target stem cells. To begin with, this is being developed for adult skin stem cells, giving hope for new drugs to promote wound healing and aid the use of stem cells to, for example, treat severe burns. This technique can also be applied to a wide range of stem cells, opening up the possibilities for harnessing stem cells in regenerative medicine.

12 Jul 2010

Report shows experimental trials have higher risk for bias

A Johns Hopkins review of nearly 150 randomized controlled trials on children - all published in well-regarded medical journals - reveals that 40 to 60 percent of the studies either failed to take steps to minimize risk for bias or to at least properly describe those measures.

12 Jul 2010

Experts use Mexican aquatic salamander to study evolution and genetics of stem cells

Dr Andrew Johnson is speaking today (12 July) at the UK National Stem Cell Network annual conference. He and his team from the University of Nottingham have been using a Mexican aquatic salamander called an axolotl to study the evolution and genetics of stem cells - research that supports the development of regenerative medicine to treat the consequences of disease and injury using stem cell therapies. This team has found that there are extraordinary similarities in the development of axolotls and mammals that provide unique opportunities to study the properties of embryonic stem cells and germ cells.

12 Jul 2010

UVA launches first-of-its-kind educational website focusing on Alzheimer's disease, dementia

The University of Virginia School of Medicine is launching Memory Commons, an interactive, first-of-its-kind educational website for physicians and healthcare professionals that focuses specifically on Alzheimer's Disease and dementia.

12 Jul 2010

Mesoblast schedules formal meeting with FDA to discuss proposed Phase 3 clinical trial program

Australian regenerative medicine company, Mesoblast Limited, today announced that based on positive results from its bone marrow transplant clinical trial conducted at the University of Texas MD Anderson Cancer Center, a formal meeting has been scheduled with the United States Food and Drug Administration to discuss a proposed Phase 3 clinical trial program.

12 Jul 2010

Subtle mutation affecting epigenome may lead to inherited form of mental retardation: Researchers

A subtle mutation affecting the epigenome –- a set of dynamic factors that influence gene activity -- may lead to an inherited form of mental retardation that affects boys, find researchers at Children's Hospital Boston. The disorder, which also involves cleft lip or cleft palate, appears to hinge on an enzyme working in a biological pathway that may offer several potential drug targets.

12 Jul 2010

Exposure to traffic-related air pollutants associated with reduced HRV: Study

In patients with pre-existing heart or lung disease, being exposed to high levels of traffic-related air pollutants is associated with reduced heart rate variability —a risk factor for sudden cardiac death, reports a study in the July Journal of Occupational and Environmental Medicine, official publication of the American College of Occupational and Environmental Medicine.

12 Jul 2010

Study examines impact of universal HIV testing, immediate ART program in Washington, DC

Implementing a program of universal HIV testing and immediate antiretroviral treatment for infected individuals could have a major impact on the HIV/AIDS epidemic in Washington, DC, but a new study finds that it would not halt the epidemic, something that a previous report had projected. In a paper that will appear in the August 15 issue of Clinical Infectious Diseases and has been released online, researchers find that the so-called "test-and-treat" strategy could reduce new HIV infections by 15 percent over the next five years while conferring large survival benefits to HIV-infected patients.

12 Jul 2010

Multimedia talking touchscreens help end health disparities in underserved populations

Multimedia talking touchscreens, housed in computer kiosks at clinics and hospitals, are helping researchers at Northwestern University Feinberg School of Medicine and clinicians at local health care centers enhance patient-centered care for patients with diverse language, literacy and computer skills.

12 Jul 2010

Alzheimer's Association recognizes four scientists for achievements in Alzheimer research at AAICAD 2010

The Alzheimer's Association recognized four scientists for their extraordinary achievements in advancing Alzheimer research at the Alzheimer's Association International Conference on Alzheimer's Disease 2010 in Honolulu, Hawaii.

12 Jul 2010

Glaxo’s diabetes pill Avandia under FDA scrutiny again

GlaxoSmithKline (GSK) is under Food and Drug Administration (FDA) scrutiny again. This is for its diabetes pill Avandia which is under review for the second time in three years.

11 Jul 2010

UM researcher uses computer algorithms to develop vaccines for new strains of influenza viruses

Defeating the flu is challenging because the virus responsible for the disease undergoes frequent changes of its genetic code, making it difficult for scientists to manufacture effective vaccines for the seasonal flu in a timely manner. Now, a University of Miami computer scientist, Dimitris Papamichail, and a team of researchers from Stony Brook University have developed a rapid and effective approach to produce vaccines for new strains of influenza viruses.

9 Jul 2010

Phase III study results of imiquimod creams for treatment of EGW presented at HPV Conference

Results from a Phase III program evaluating imiquimod 3.75% and 2.5% creams for the treatment of EGW, applied once daily for up to 8 weeks, demonstrated that both were well-tolerated and more efficacious than placebo, according to data presented at the annual Human Papillomavirus Conference in Montreal, July 3 - 8. Investigators found that efficacy was greatest for imiquimod 3.75% with an enhanced safety profile.

9 Jul 2010

Serum BNP do not increase in pediatric trauma patients with serious head injuries: Report

Investigators at Childrens Hospital Los Angeles have found that unlike adults, levels of serum beta-natriuretic peptide do not increase in pediatric trauma patients with serious head injuries.

9 Jul 2010

UMMC to partner with Mayo Clinic to discover new therapies, train new medical scientists

The University of Mississippi Medical Center will partner with the renowned Mayo Clinic on a series of initiatives intended to convert laboratory discoveries into new therapies and train a new generation of medical scientists.

9 Jul 2010

Tulane University to receive $11.2M over seven years to establish international malaria research center

Tulane University will receive approximately $11.2 million over seven years from the National Institute of Allergy and Infectious Diseases, a division of the National Institutes of Health, to establish an International Center of Excellence in Malaria Research for West and Central Africa. The money will be awarded in response to a multi-institutional proposal from Tulane University School of Public Health and Tropical Medicine.

9 Jul 2010

Lantheus signs new manufacturing, supply agreement with MDS Nordion for Mo-99

Lantheus Medical Imaging, Inc., a worldwide leader in diagnostic medical imaging, today announced that it has signed a new manufacturing and supply agreement with MDS Nordion to purchase molybdenum-99 (Mo-99), the parent isotope of technetium-99m (Tc-99m). Mo-99 is used in Lantheus Medical Imaging's TechneLite® (Technetium Tc99m Generator) generators, which are sold throughout the world, and which produce Tc-99m, a medical isotope widely used in nuclear medicine imaging.

9 Jul 2010

Semuloparin reduces incidence of VTE in orthopedic surgery patients, study finds

An ultra-low-molecular-weight heparin called semuloparin has been found to reduce the incidence of venous thromboembolism in orthopedic surgery patients in a large clinical program being lead by a steering committee chaired by McMaster University professor Dr. Alexander Turpie.

9 Jul 2010

Study on Drosophila flies may help develop treatments for serious human diseases: Article

A Science article published on July 9, 2010, describes the discovery of an alternative form of evolution that helps Drosophila flies conquer nematodes that sterilize them. Nematodes are among the most abundant, diverse and destructive parasites of plants and animals.

9 Jul 2010

Simple, routine test for detecting subtle onset of diabetes and prediabetes

Having discovered a dramatic increase of an easy-to-detect enzyme in the red blood cells of people with diabetes and prediabetes, Johns Hopkins scientists say the discovery could lead to a simple, routine test for detecting the subtle onset of the disease, before symptoms or complications occur and in time to reverse its course.

9 Jul 2010

Medicine News and Research

New approach of screening drugs that encourage stem cells to repair damaged tissue

Report shows experimental trials have higher risk for bias

Experts use Mexican aquatic salamander to study evolution and genetics of stem cells

UVA launches first-of-its-kind educational website focusing on Alzheimer's disease, dementia

Mesoblast schedules formal meeting with FDA to discuss proposed Phase 3 clinical trial program

Subtle mutation affecting epigenome may lead to inherited form of mental retardation: Researchers

Exposure to traffic-related air pollutants associated with reduced HRV: Study

Study examines impact of universal HIV testing, immediate ART program in Washington, DC

Multimedia talking touchscreens help end health disparities in underserved populations

Alzheimer's Association recognizes four scientists for achievements in Alzheimer research at AAICAD 2010

Glaxo’s diabetes pill Avandia under FDA scrutiny again

UM researcher uses computer algorithms to develop vaccines for new strains of influenza viruses

Phase III study results of imiquimod creams for treatment of EGW presented at HPV Conference

Serum BNP do not increase in pediatric trauma patients with serious head injuries: Report

UMMC to partner with Mayo Clinic to discover new therapies, train new medical scientists

Tulane University to receive $11.2M over seven years to establish international malaria research center

Lantheus signs new manufacturing, supply agreement with MDS Nordion for Mo-99

Semuloparin reduces incidence of VTE in orthopedic surgery patients, study finds

Study on Drosophila flies may help develop treatments for serious human diseases: Article

Simple, routine test for detecting subtle onset of diabetes and prediabetes

Everything there is to know about biosimilars eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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