Protein C News and Research

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What is the long-term durability of plasma cells in human bone marrow?

In a new study, researchers assessed the long-term durability of plasma cells in the human bone marrow.

16 Aug 2022

Computational pipeline for the early identification of emerging SARS-CoV-2 variants

Researchers developed a computational pipeline for the early identification of emerging SARS-CoV-2 variants of interest by analyzing SARS-CoV-2 genome data and allocating risk scores on the basis of functional and epidemiological parameters.

16 Aug 2022

Rapid and efficient strategy for the development and design of SARS-CoV-2 neutralizing humanized nanobody constructs

Researchers developed humanized nanobodies that neutralize SARS-CoV-2.

16 Aug 2022

$$13 million PCORI funding aims to support the study of fracture prevention strategies for osteoporosis$

$13 million PCORI funding aims to support the study of fracture prevention strategies for osteoporosis

University of Maryland School of Medicine faculty from the Department of Epidemiology & Public Health and the Department of Physical Therapy and Rehabilitation Science are co-recipients of a $13 million funding award from the Patient-Centered Outcomes Research Institute to compare interventions used to improve mobility and prevent future fractures in older adults recovering from a hip or leg fracture.

15 Aug 2022

Researchers engineer artificial replicas of G protein-coupled receptors

How do signals from outside the cell cause a response inside it? Such outside signals could be hormones or neurotransmitters. To notice them, the cell's surface possesses receptors. One of the key classes of such receptors are so-called G protein-coupled receptors, or in short GPCRs.

15 Aug 2022

Scientists explore nanomolar inhibition of SARS-CoV-2 infection via unmodified peptide targeting spike protein pre-hairpin intermediate

In a new study, scientists identified an unmodified peptide addressing pre-hairpin spike (S) protein intermediate inhibiting SARS-CoV-2 infection.

15 Aug 2022

SARS-CoV-2 S protein and RNA fragments remain in convalescent SARS-CoV-2 patients with PASC

Researchers evaluated circulating SARS-CoV-2 elements in long coronavirus disease.

15 Aug 2022

Study shows astrocytes as breeding grounds of SARS-CoV-2 during brain infection

Researchers evidenced the presence of SARS-CoV-2 in the human brain, infecting astrocytes and impairing neuronal function and viability.

15 Aug 2022

Is the level of circulating SARS-CoV-2 RNA or spike protein associated with acute disease severity?

Researchers investigated the levels of circulating SARS-CoV-2 spike protein and viral RNA among patients hospitalized with acute COVID-19 and in patients with and without post-acute sequelae of COVID-19.

15 Aug 2022

Do pre-existing antibodies alter the development of memory B cells in response to SARS-CoV-2 mRNA vaccination in humans?

Researchers explored how passive administration of monoclonal antibodies impact the development of immunological memory in response to COVID-19 vaccination.

15 Aug 2022

How well does hybrid immunity protect against SARS-CoV-2 and its variants?

A new study explores the protection elicited by hybrid immunity against SARS-CoV-2 variants.

14 Aug 2022

Why is COVID-19 more severe in people older than 50?

A new study reports that the reduced efficiency of the immune response against SARS-CoV-2 could be due to the reduced diversity of both B- and T-cells.

14 Aug 2022

Mechanistic insights into engineered ACE2 receptor traps

Researchers determined the cryo-electron microscopic (cryo-EM) structures of engineered angiotensin-converting enzyme 2 (ACE2) receptor traps.

12 Aug 2022

Bispecific antibody exhibits high breadth and potency against SARS-CoV-2 Omicron sub-lineages

In a new study, researchers developed bispecific-antibodies (bsAbs) against SARS-CoV-2 Omicron sub-lineages.

12 Aug 2022

What is the genomic diversity of SARS-CoV-2 infections in households?

In a new study, researchers assessed the genomic diversity of SARS-CoV-2 in households.

12 Aug 2022

Influence of SARS-CoV-2 breakthrough infection and age on humoral immunity post-three-dose COVID-19 vaccination

In a new study, researchers briefly reported the effect of SARS-CoV-2 breakthrough infection and age on humoral immunity following triple-dose SARS-CoV-2 messenger ribonucleic acid (mRNA) vaccination.

12 Aug 2022

Remdesivir activates urotensin II receptor and induces cardiomyocyte dysfunction

In newly released research, scientists assessed the cardiac effects of remdesivir.

12 Aug 2022

What is the association between diet of lactating mothers and breast milk oxidant-antioxidant status?

Researchers assessed the association between maternal diet and the oxidant-antioxidant status in breast milk.

12 Aug 2022

How does COVID-19 increase clotting risk?

An in-depth review article describing coronavirus disease 2019 (COVID-19)-related coagulopathy has recently been published in the journal Nature Reviews Immunology.

11 Aug 2022

Vaccines and monoclonal antibodies being developed for respiratory syncytial virus

A new study reviews recent advancements made in the development of RSV immunoprophylactic measures.

11 Aug 2022

Protein C News and Research

What is the long-term durability of plasma cells in human bone marrow?

Computational pipeline for the early identification of emerging SARS-CoV-2 variants

Rapid and efficient strategy for the development and design of SARS-CoV-2 neutralizing humanized nanobody constructs

$13 million PCORI funding aims to support the study of fracture prevention strategies for osteoporosis

Researchers engineer artificial replicas of G protein-coupled receptors

Scientists explore nanomolar inhibition of SARS-CoV-2 infection via unmodified peptide targeting spike protein pre-hairpin intermediate

SARS-CoV-2 S protein and RNA fragments remain in convalescent SARS-CoV-2 patients with PASC

Study shows astrocytes as breeding grounds of SARS-CoV-2 during brain infection

Is the level of circulating SARS-CoV-2 RNA or spike protein associated with acute disease severity?

Do pre-existing antibodies alter the development of memory B cells in response to SARS-CoV-2 mRNA vaccination in humans?

How well does hybrid immunity protect against SARS-CoV-2 and its variants?

Why is COVID-19 more severe in people older than 50?

Mechanistic insights into engineered ACE2 receptor traps

Bispecific antibody exhibits high breadth and potency against SARS-CoV-2 Omicron sub-lineages

What is the genomic diversity of SARS-CoV-2 infections in households?

Influence of SARS-CoV-2 breakthrough infection and age on humoral immunity post-three-dose COVID-19 vaccination

Remdesivir activates urotensin II receptor and induces cardiomyocyte dysfunction

What is the association between diet of lactating mothers and breast milk oxidant-antioxidant status?

How does COVID-19 increase clotting risk?

Vaccines and monoclonal antibodies being developed for respiratory syncytial virus

Event guide: 4th Extra-Hepatic Lipid-Based Nanoparticles Delivery Summit eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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