Receptor News and Research

RSS

Re-engineered plant compound reduces morphine-seeking behaviors in mice

The abuse of prescription and illegal opioids, such as morphine and heroin, is a major problem in the U.S., with devastating public health, economic and social consequences.

5 Feb 2020

Novel hydrogels degrade while stem cells flourish for tissue repair

Baby diapers, contact lenses and gelatin dessert. While seemingly unrelated, these items have one thing in common -- they're made of highly absorbent substances called hydrogels that have versatile applications.

4 Feb 2020

New treatment target for acute kidney injury prevention revealed

Up to 10% of patients who are hospitalized or undergo surgery will experience acute kidney injury, and as many as 50% of patients in intensive care units will meet the criteria for AKI, the National Kidney Foundation has determined. Some of these patients will progress to kidney failure within months.

4 Feb 2020

Researchers develop an emergency stop switch for CAR T-cell therapies

Immunotherapy, unlike chemotherapy and radiotherapy, arms the body's immune system to attack cancer cells. In recent years, it has proven to be remarkably successful at treating leukemia, lymphoma and other liquid cancers, or cancers present in body fluids.

4 Feb 2020

Ludwig Cancer Research study develops a safer CAR-T therapy

A Ludwig Cancer Research study has devised a new type of chimeric antigen-receptor (CAR) T cell - a family of promising immunotherapies for cancer- that can be switched on and off on demand.

3 Feb 2020

FDA gives clearance to IND application for Calibr's 'switchable' CAR-T cell therapy

Calibr, the drug discovery and development division of Scripps Research, today announced that the U.S. Food and Drug Administration has given clearance to the Investigational New Drug (IND) application for Calibr's "switchable" CAR-T cell therapy, which is being evaluated for the treatment of certain cancers, including relapsed/refractory B-cell malignancies such as non-Hodgkin lymphoma and chronic lymphocytic leukemia.

3 Feb 2020

UTHSC researchers receive $1.98 million grant for novel approach to studying diabetes

A team of researchers in the University of Tennessee Health Science Center's College of Medicine has been awarded a $1.98 million grant from the National Institute of Diabetes and Digestive and Kidney Disease, a division of the National Institutes of Health, for a novel approach to studying diabetes.

3 Feb 2020

Reduced scar formation in the central nervous system

Neural stem and progenitor cells, from the so-called subventricular zone, can help to repair a brain damaged by central nervous system disorders.

3 Feb 2020

Discovery about how cancer cells hide from the immune system could improve treatments

Researchers have shed light on the mechanism through which cancer cells become camouflaged to escape immune system detection and attack.

31 Jan 2020

New discovery could enable scientists to fine-tune activity of cancer-killing immune cells

A discovery by University of North Carolina Lineberger Comprehensive Cancer Center researchers could allow scientists to fine-tune genetically engineered immune cells to heighten their killing power against tumors or to decrease their activity level in the case of severe side effects.

31 Jan 2020

Wuhan coronavirus is genetically different from human SARS, MERS-CoV, study found

The Wuhan coronavirus or the 2019-nCoV or novel coronavirus is a new human-infecting coronavirus genetically different from human SARS (Severe Acute Respiratory Syndrome), and MERS-CoV (Middle East Respiratory Syndrome), a team of scientists has found.

30 Jan 2020

Death receptor pathway drives resistance to CAR T cell therapy

Some cancer cells refuse to die, even in the face of powerful cellular immunotherapies like CAR T cell therapy, and new research from the Abramson Cancer Center of the University of Pennsylvania is shedding light on why.

30 Jan 2020

New target protein linked to regulation, movement of tumor-associated macrophages

Developing a therapy to combat cancer remains one of the most difficult challenges in medical research. Cancer owes its notorious identity to the fact that the cancer cells use the host's own immune system to grow and spread, ultimately becoming deadly.

30 Jan 2020

New treatment target could change the outlook of patients at risk of kidney injury

Kidney injury is a dreaded complication of commonly performed procedures such as coronary angiography or cardiac surgery, often stopping physicians and patients in their tracks.

30 Jan 2020

Findings shed new light on how striatum processes information to plan, execute movements

Researchers at Karolinska Institutet have mapped how different nerve cells in the brain area striatum process information to plan and execute our movements at just the right time and with the right vigour. The results, presented in the journal Cell Reports, show that different cell types in the striatum receive signals from completely different parts of the cerebral cortex and thus respond to different types of information.

28 Jan 2020

Study finds unexpected response to estrogen at the single cell level

A team led by researchers at Baylor College of Medicine found that not only do individual mammalian cells in a population fail to respond synchronously to estrogen stimulation, neither do individual gene copies, known as alleles.

28 Jan 2020

Taming pathogens with mucus and phages

Millions of people are treated with antibiotics each year for infections or as a preventative measure. The Centers for Disease Control and Prevention reports that at least 2.8 million people are infected with antibiotic-resistant bacteria each year, meaning the germs have found ways to overpower antibiotics and continue to grow.

24 Jan 2020

First glioblastoma patient treated with genetically modified poliovirus at UH

University Hospitals Seidman Cancer Center treated its first patient in a new clinical trial to validate the groundbreaking effects of the poliovirus on glioblastoma, a deadly Grade IV cancer of the brain.

24 Jan 2020

Scientists visualize diabetes-related proteins at high resolution

Scientists have examined a key receptor for the first time at high resolution - broadening understanding of how it might function, and opening the door to future improvements in treating conditions such as type 2 diabetes.

24 Jan 2020

Study reveals new "crosstalk" between intestinal microbes and developing thymic cells

Newborns face unique immunological challenges immediately after birth. As they depart a relatively sterile fetal environment, they are abruptly exposed to a multitude of foreign antigens, the major burden of which is in the form of the microbiota newly colonizing the gastrointestinal tract.

24 Jan 2020

Receptor News and Research

Re-engineered plant compound reduces morphine-seeking behaviors in mice

Novel hydrogels degrade while stem cells flourish for tissue repair

New treatment target for acute kidney injury prevention revealed

Researchers develop an emergency stop switch for CAR T-cell therapies

Ludwig Cancer Research study develops a safer CAR-T therapy

FDA gives clearance to IND application for Calibr's 'switchable' CAR-T cell therapy

UTHSC researchers receive $1.98 million grant for novel approach to studying diabetes

Reduced scar formation in the central nervous system

Discovery about how cancer cells hide from the immune system could improve treatments

New discovery could enable scientists to fine-tune activity of cancer-killing immune cells

Wuhan coronavirus is genetically different from human SARS, MERS-CoV, study found

Death receptor pathway drives resistance to CAR T cell therapy

New target protein linked to regulation, movement of tumor-associated macrophages

New treatment target could change the outlook of patients at risk of kidney injury

Findings shed new light on how striatum processes information to plan, execute movements

Study finds unexpected response to estrogen at the single cell level

Taming pathogens with mucus and phages

First glioblastoma patient treated with genetically modified poliovirus at UH

Scientists visualize diabetes-related proteins at high resolution

Study reveals new "crosstalk" between intestinal microbes and developing thymic cells

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Latest News