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Discarded livers have potential to be reengineered into usable replacement organs: Researchers

A team led by researchers from the Center for Engineering in Medicine at Massachusetts General Hospital has developed a technique that someday may allow growth of transplantable replacement livers. In their report that will be published in Nature Medicine and is receiving early online release, the investigators describe using the structural tissue of rat livers as scaffolding for the growth of tissue regenerated from liver cells introduced through a novel reseeding process.

14 Jun 2010

HHS announces grants to support States' efforts to implement, evaluate patient safety approaches

The Department of Health and Human Services' Agency for Healthcare Research and Quality today announced grants to support efforts by States and health systems to implement and evaluate patient safety approaches and medical liability reforms. The demonstration and planning grants are part of the patient safety and medical liability initiative that President Obama announced during a September 9, 2009 address to a joint session of Congress.

14 Jun 2010

Telmisartan reduces hypertension, cardiovascular risk in ACE-intolerant patients: Boehringer Ingelheim

Telmisartan, an angiotensin receptor blocker, is one of the best researched drugs worldwide. It has been studied in clinical trials in more than 50,000 patients. Its positive safety profile has been confirmed also in a market exposure of 34.5 million patient years. Convincing safety data for patients with a high cardiovascular risk were collected in the three long-term outcome trials ONTARGET, PRoFESS and TRANSCEND which followed some of the patients for up to five years.

14 Jun 2010

CNVs increases patients' susceptibility to severe sepsis

Genetic makeup has been identified as a key factor leading to the development of sepsis, a systemic inflammatory reaction that occurs during infection. Sepsis is considered severe when associated with organ dysfunction.

14 Jun 2010

Researchers discover key factor in beading mechanism

Researchers at Rice University, Purdue University and the Massachusetts Institute of Technology have solved a long-standing mystery about why some fluids containing polymers -- including saliva -- form beads when they are stretched and others do not.

14 Jun 2010

New guideline to improve IHC testing for expression status of ER and PgR in breast cancer issued

The College of American Pathologists and the American Society of Clinical Oncology today issued a joint guideline aimed at improving the accuracy of immunohistochemistry testing for the expression status of estrogen and progesterone receptors in breast cancer. The two groups conducted a systematic review of medical research literature in partnership with Cancer Care Ontario to develop the recommendations.

14 Jun 2010

Chiasma successfully completes Phase I clinical study of Octreolin

Chiasma, Inc., a privately held biopharma company, announced that it has successfully completed a Phase I clinical study evaluating the safety and pharmacokinetics (PK) of its proprietary product Octreolin, which contains the active ingredient octreotide actetate and is administered orally

14 Jun 2010

U.S. HealthWorks announces acquisition of Sierra Occupational Services healthcare center

U.S. HealthWorks, the leading operator of occupational healthcare centers in California, today announced the acquisition of the Sierra Occupational Services healthcare center at 1429 West Fremont Street in Stockton. The acquisition of this center expands the number of U.S. HealthWorks operated medical centers to 66 in California and 134 nationwide.

14 Jun 2010

Trauma patients without insurance more likely to die of injuries than privately insured patients: Study

Trauma patients without insurance are more likely to die of their injuries from auto accidents and gunshot wounds than privately insured patients with similar injuries, according to findings of an analysis of 193,804 patients from 649 facilities conducted by University Buffalo emergency medicine physicians.

14 Jun 2010

Researchers identify 2,630 proteins that reside in human spinal fluid

A research team has sharply expanded scientific knowledge of the composition of human spinal fluid. The researchers have identified 2,630 proteins that reside in fluid that is considered "normal," a number nearly three times as great as the total number of proteins previously identified. Another striking finding was that more than half (56%) of the proteins were relatively unique to the spinal fluid and not found in blood.

14 Jun 2010

Children living in socially disadvantaged neighborhoods are more likely to be obese

Children in King County, Washington, are more likely to be obese if they live in socially disadvantaged neighborhoods. This is according to a team of researchers at Seattle Children's Research Institute, the University of Washington (UW), and Group Health Research Institute. Social Science & Medicine e-published the research this week in advance of printing it.

14 Jun 2010

DFG sets up new Research Training Groups for German researchers

To further enhance the promotion of young researchers in Germany, the Deutsche Forschungsgemeinschaft (DFG, German Research Foundation) has established twelve new Research Training Groups.

14 Jun 2010

Community-based model of DOT improves HIV patient survival: Researchers

When applied to HIV care, the community-based model of directly observed therapy has no effect on virologic outcomes, but significantly improves patient survival. This is according to researchers at the Johns Hopkins Bloomberg School of Public Health, in collaboration with colleagues at University of Cape Town, South Africa, who conducted the first randomized controlled trial of patient-nominated treatment-supporters providing partial DOT in resource-limited settings.

11 Jun 2010

Medicare drug spending varies by region, does not offset other medical costs

A study has found that Medicare spending on drugs varies significantly in different regions, and that increased drug spending isn't offset by lower spending on hospital care, doctors visits and other health services, HealthDay/Bloomberg Businessweek reports.

11 Jun 2010

HHS announces grants to implement and evaluate patient safety approaches, medical liability reforms

11 Jun 2010

DRIVE4COPD initiative aims to raise awareness of COPD

In just four months since its launch, DRIVE4COPD has already encouraged more than 100,000 people to be screened to see if they may be at risk for chronic obstructive pulmonary disease. The country's newest health initiative that aims to raise awareness of COPD in the hopes that people will talk to their doctor and get diagnosed instead of suffering in silence. Currently, half of the estimated 24 million Americans who may have COPD remain undiagnosed and untreated, and most are not diagnosed until they have lost half their lung function.

11 Jun 2010

Phase II study results of riociguat for CTEPH and PAH published online

Bayer HealthCare Pharmaceuticals, Inc. today announced that the study "Riociguat for chronic thromboembolic pulmonary hypertension and pulmonary arterial hypertension: a phase II study" was published online this week by the European Respiratory Journal. Results of this study to assess the safety, tolerability and the feasibility of individual dose titration of riociguat were previously presented at the 2009 International Conference of the American Thoracic Society.

11 Jun 2010

Boston Scientific announces event schedule at 17th Cardiostim World Congress

Boston Scientific Corporation today announced the schedule of the Company's key events and sponsored research at the 17th Cardiostim World Congress, June 16 – 19 in Nice, France.

11 Jun 2010

Waismann Method survey: 88% of individuals taken prescription painkillers for chronic pain relief

According to a recent survey conducted by the Waismann Method of opiate detoxification, doctors prescribing medication for the treatment of chronic pain were found to be the leading source of prescription painkiller use. Approximately 88 percent of all respondents stated they began taking prescription painkillers for chronic pain relief, with an astounding 70 percent of these individuals believing that they experience the same or a greater amount of pain than when originally prescribed painkillers.

11 Jun 2010

Sundise to implement Medidata Rave as its EDC and CDM solution

Medidata Solutions, a leading global provider of SaaS-based clinical development solutions, today announced that Traditional Chinese Medicine company Sundise will implement Medidata Rave as its electronic data capture and clinical data management solution. Selected for its ability to offer a broad global reach with local in-country support, Medidata will work with Sundise to conduct its first U.S. trial for its TCM treatment for liver fibrosis and will play a key role in supporting the company's strategy to launch in the U.S.

11 Jun 2010

Medicine News and Research

Discarded livers have potential to be reengineered into usable replacement organs: Researchers

HHS announces grants to support States' efforts to implement, evaluate patient safety approaches

Telmisartan reduces hypertension, cardiovascular risk in ACE-intolerant patients: Boehringer Ingelheim

CNVs increases patients' susceptibility to severe sepsis

Researchers discover key factor in beading mechanism

New guideline to improve IHC testing for expression status of ER and PgR in breast cancer issued

Chiasma successfully completes Phase I clinical study of Octreolin

U.S. HealthWorks announces acquisition of Sierra Occupational Services healthcare center

Trauma patients without insurance more likely to die of injuries than privately insured patients: Study

Researchers identify 2,630 proteins that reside in human spinal fluid

Children living in socially disadvantaged neighborhoods are more likely to be obese

DFG sets up new Research Training Groups for German researchers

Community-based model of DOT improves HIV patient survival: Researchers

Medicare drug spending varies by region, does not offset other medical costs

HHS announces grants to implement and evaluate patient safety approaches, medical liability reforms

DRIVE4COPD initiative aims to raise awareness of COPD

Phase II study results of riociguat for CTEPH and PAH published online

Boston Scientific announces event schedule at 17th Cardiostim World Congress

Waismann Method survey: 88% of individuals taken prescription painkillers for chronic pain relief

Sundise to implement Medidata Rave as its EDC and CDM solution

Industry Focus eBook - Cell & Gene Therapy (1st Edition) eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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