Protein C News and Research

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Researchers create the most bio-realistic and complex computer models of brain cells

Cedars-Sinai investigators have created the most bio-realistic and complex computer models of individual brain cells - in unparalleled quantity.

9 Aug 2022

Researchers develop a potential way to tackle one of the underlying causes of asthma

A possible way to tackle one of the underlying causes of asthma has been developed by researchers from Aston University and Imperial College London.

9 Aug 2022

Double mRNA COVID-19 vaccination found to increase SARS-CoV-2 variant recognition

Researchers evaluated the impact of double BNT162b2 messenger ribonucleic acid (mRNA) vaccination in recognition of SARS-CoV-2 variants of concern.

9 Aug 2022

A genome-wide catalog of rare copy-number variant associations for 54 disease phenotypes

A recent study published in Cell illustrated a human genome map with dosage sensitivity across disorders.

9 Aug 2022

The neutralizing activity of a panel of 482 human monoclonal antibodies against Omicron BA.4 and BA.5

Researchers demonstrated differential utilization of the B cell germlines and SARS-CoV-2 spike protein epitopes by cross-neutralizing antibodies in infected, vaccinated and individuals with hybrid immunity.

9 Aug 2022

How does the interval between the 1st and 2nd BNT162b2 doses impact the neutralization breadth and potency against variants of concern?

Scientists explored the influence of SARS-CoV-2 extended gap vaccination on the variants of concern neutralization.

9 Aug 2022

Study suggests BA.5 evolved to induce enhanced inflammation when compared to prior Omicron subvariants

Researchers evaluated the comparative pathogenicity of SARS-CoV-2 Omicron sub-variants BA.1, BA.2, and BA.5, in vitro and in vivo.

9 Aug 2022

Alzheimer’s disease is associated with characteristic gut metabolomic signatures

Scientists review current literature associated with the role of the gut-brain axis in AD pathogenesis.

9 Aug 2022

Aldosterone may increase risk of kidney failure in patients with chronic kidney disease

A steroid hormone called aldosterone is linked to an increased risk of kidney failure in patients with chronic kidney disease (CKD), according to a study published in the European Heart Journal today (Tuesday).

8 Aug 2022

Researchers synthesize a small molecule that can be used to treat a range of cancers

Researchers at Tel Aviv University and the University of Lisbon have jointly identified and synthesized a small molecule that could be a more accessible and effective alternative to an antibody that is successfully used to treat a range of cancers.

8 Aug 2022

Disruption of the circadian clocks plays a key role in weight gain

Disruption of the circadian clocks that keep the body and its cells entrained to the 24-hour day-night cycle plays a critical role in weight gain, according to a pair of studies by Weill Cornell Medicine investigators.

8 Aug 2022

COVID-19 vaccination increases antibodies in breast milk significantly

Anti-SARS-CoV-2 antibodies in breast milk capable of neutralizing both an early pandemic SARS-CoV-2 isolate and Omicron variant.

8 Aug 2022

New insights into the understanding of how ApoE variants contribute to Tau pathology in Alzheimer’s disease

Researchers examined the impact of tau neuropathology of APOE3 Christchurch (APOE3ch) homozygote against Alzheimer’s disease.

8 Aug 2022

Scientists find key molecular differences between breast cancer cells in initial and metastatic tumors

Studying a deadly type of breast cancer called triple negative, Johns Hopkins Medicine scientists say they have identified key molecular differences between cancer cells that cling to an initial tumor and those that venture off to form distant tumors.

8 Aug 2022

Study tests equine polyclonal antibodies against SARS-CoV-2 variants

A recent study published tested equine polyclonal antibodies against SARS-CoV-2.

8 Aug 2022

Inhaled aprotinin found to reduce viral load in mild-to-moderate COVID-19

A recent paper describes the use of aprotinin, a protease inhibitor that works across several pathways, to reduce the severity of COVID-19.

8 Aug 2022

The safety and preliminary efficacy of OP-101 in patients with severe COVID-19

Researchers assessed the impact of dendrimer nanotherapy in treating severe COVID-19.

8 Aug 2022

Assessing immunization capacity of vaccine platforms with DNA origami harboring SARS-CoV-2 receptor binding domain

Researchers demonstrated that vaccine frameworks containing deoxyribonucleic acid (DNA) origami possessing SARS-CoV-2 receptor-binding domain induce strong protective immunity.

8 Aug 2022

Researchers create a physical wiring diagram of the human immune system

In a new study, researchers systematically mapped the surface proteins on human leukocytes to examine interactions between their cell-surface proteomes and develop a physical wiring diagram encapsulating the diversity of surface protein architectures found across all major subsets of leukocytes.

8 Aug 2022

How can we map the human genetic architecture of COVID-19 across all ancestry groups?

In a new study, researchers formed the COVID-19 host genetics initiative to compile a genome-wide association meta-analysis of 60 studies from 25 countries.

8 Aug 2022

Protein C News and Research

Researchers create the most bio-realistic and complex computer models of brain cells

Researchers develop a potential way to tackle one of the underlying causes of asthma

Double mRNA COVID-19 vaccination found to increase SARS-CoV-2 variant recognition

A genome-wide catalog of rare copy-number variant associations for 54 disease phenotypes

The neutralizing activity of a panel of 482 human monoclonal antibodies against Omicron BA.4 and BA.5

How does the interval between the 1st and 2nd BNT162b2 doses impact the neutralization breadth and potency against variants of concern?

Study suggests BA.5 evolved to induce enhanced inflammation when compared to prior Omicron subvariants

Alzheimer’s disease is associated with characteristic gut metabolomic signatures

Aldosterone may increase risk of kidney failure in patients with chronic kidney disease

Researchers synthesize a small molecule that can be used to treat a range of cancers

Disruption of the circadian clocks plays a key role in weight gain

COVID-19 vaccination increases antibodies in breast milk significantly

New insights into the understanding of how ApoE variants contribute to Tau pathology in Alzheimer’s disease

Scientists find key molecular differences between breast cancer cells in initial and metastatic tumors

Study tests equine polyclonal antibodies against SARS-CoV-2 variants

Inhaled aprotinin found to reduce viral load in mild-to-moderate COVID-19

The safety and preliminary efficacy of OP-101 in patients with severe COVID-19

Assessing immunization capacity of vaccine platforms with DNA origami harboring SARS-CoV-2 receptor binding domain

Researchers create a physical wiring diagram of the human immune system

How can we map the human genetic architecture of COVID-19 across all ancestry groups?

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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