Brain Tumor News and Research

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A Brain Tumor is the growth of abnormal cells in the tissues of the brain. Brain tumors can be benign (not cancer) or malignant (cancer).

Conventional repeated radiation treatments may offer no major benefit to brain tumor patients

A new study shows that repeated radiation therapy used to target tumors in the brain may not be as safe to healthy brain cells as previously assumed.

19 May 2016

Histone mutation linked to fatal pediatric brain tumor

A single defect in a gene that codes for a histone — a "spool" that wraps idle DNA — is linked to pediatric cancers in a study published today in the journal Science.

13 May 2016

Sophisticated technology helps model and simulate optimal dose for pediatric ependymoma patients

St. Jude Children's Research Hospital scientists have used sophisticated pharmacologic modeling and simulation to translate preclinical findings into a successful phase I clinical trial of a chemotherapy agent for treatment of ependymoma. The research marked the first time the approach has been used to calculate drug doses for a clinical trial in pediatric brain tumor patients.

10 May 2016

Experimental therapy stops glioblastoma, high-grade gliomas in human cells and mouse models

Researchers report in the journal Cancer Cell an experimental therapy that in laboratory tests on human cells and mouse models stops aggressive, treatment-resistant and deadly brain cancers called glioblastoma and high-grade gliomas.

10 May 2016

Barrow research focuses on use of new technology for imaging brain tumors

Scientists at Barrow Neurological Institute have recently made discoveries about use of a new technology for imaging brain tumors in the operating room -- a finding that could have important implications for identifying and locating invading cells at the edge of a brain tumor.

5 May 2016

Study reveals glioblastoma subtypes tend to develop in different regions of the brain

Researchers at University of California San Diego School of Medicine have demonstrated that distinct types of glioblastoma, the most common form of brain cancer in adults, tend to develop in different regions of the brain. This finding provides an explanation for how the same cancer-causing mutation can give rise to different types of brain malignancies.

5 May 2016

Proton therapy offers new hope to patients with inoperable tumors

An enormous high tech machine is providing new hope to patients across the country with inoperable tumors. Proton therapy is a precise radiation technique that reduces the side effects often accompanied by traditional treatment options. Thanks to this remarkable technology, a new proton therapy center at UF Health Cancer Center - Orlando Health is saving the eyesight of a new mother who was diagnosed with a tumor behind her eye during her second trimester of pregnancy.

5 May 2016

OSMR gene plays key role in driving growth of glioblastoma tumors

Glioblastoma is the most aggressive type of brain tumor in adults. Unfortunately, there are no effective treatments for the disease. On average, patients succumb just 16 months after diagnosis.

27 Apr 2016

Low-carbohydrate diet helps reduce growth of glioblastoma tumor cells in mouse models

University of Florida Health researchers have slowed a notoriously aggressive type of brain tumor in mouse models by using a low-carbohydrate diet.

16 Apr 2016

Radiation plus chemotherapy improves survival of low-grade brain cancer patients

New clinical-trial findings show that patients with a low-grade form of brain cancer who are treated with radiation plus a combination of chemotherapy drugs have better survival than patients treated with radiation alone.

16 Apr 2016

Radiation therapy plus PCV chemotherapy improves survival of low-grade glioma patients

Patients with a low-grade type of brain tumor called glioma who received radiation therapy plus a chemotherapy regimen, including procarbazine, lomustine and vincristine (PCV), experienced a longer progression-free survival and overall survival than patients who received radiation therapy alone, according to the results of the clinical trial, Radiation Therapy Oncology Group 9802 published in the April 7 issue of the New England Journal of Medicine.

7 Apr 2016

Compound from unique blue-green algae could be key to next anti-cancer drug

Could a slippery glob of algae hold the key to the next anti-cancer drug? According to new research into a compound produced by a unique community of blue-green algae, the answer could be yes.

7 Apr 2016

Altered metabolism of two essential amino acids helps drive development of glioblastoma

The altered metabolism of two essential amino acids helps drive the development of the most common and lethal form of brain cancer, according to a new study led by researchers at The Ohio State University Comprehensive Cancer Center - Arthur G. James Cancer Hospital and Richard J. Solove Research Institute.

2 Apr 2016

Researchers develop metastasis-on-a-chip system to advance cancer investigation, drug discovery

Advances in personalized medicine allow doctors to select the most promising drugs for certain types of malignant tumors.

24 Mar 2016

Tews Laboratory uses LaVision BioTec UltraMicroscope to study molecular mechanisms of tumor invasion

LaVision BioTec, developers of advanced microscopy solutions for the life sciences, report on the work in the Tews Laboratory which is studying the molecular mechanisms of tumor invasion using an UltraMicroscope for enhanced imaging of cells.

22 Mar 2016

DelMar's VAL-083 receives FDA orphan drug designation for treatment of medulloblastoma

DelMar Pharmaceuticals, Inc., announced today that the FDA Office of Orphan Products Development (OOPD) has granted orphan drug designation for its lead product candidate, VAL-083, in the treatment of medulloblastoma.

15 Mar 2016

Expression of BIRC3 protein associated with poor survival, recurrent disease in GBM patients

Glioblastoma multiforme (GBM) is a highly aggressive brain tumor with low survival rates, with newly diagnosed patients surviving a median of 14 months and recurrent patients surviving a median of only 3 to 9 months. New therapeutic targets and biomarkers for prognosis are urgently needed.

7 Mar 2016

Strange Glow: New book seeks to remove mystery that surrounds radiation

Strange Glow tells the story of man's encounter with radiation, and how mankind has been transformed by the experience. The book focuses on a health-centric perspective "that seeks to remove some of the mystery and misunderstanding that surrounds radiation," says Jorgensen, director of the Health Physics and Radiation Protection Graduate Program, and chair of Georgetown's Radiation Safety Committee.

4 Mar 2016

Renishaw inVia to support development of nanomolecular probes in Kircher Laboratory at Memorial Sloan Kettering

The Kircher laboratory at Memorial Sloan Kettering is developing novel nanoprobes for molecular imaging, image-guided therapy and theranostics.

4 Mar 2016

Study provides critical insight into Warburg effect

PGK1, a glycolytic enzyme, has been found to play a role in coordinating cellular processes crucial to cancer metabolism and brain tumor formation, according to results published in today's online issue of Molecular Cell. The findings may lay the groundwork for improved approaches to diagnosis and treatment of glioblastoma and other cancers.

4 Mar 2016

Brain Tumor News and Research

Further Reading

Conventional repeated radiation treatments may offer no major benefit to brain tumor patients

Histone mutation linked to fatal pediatric brain tumor

Sophisticated technology helps model and simulate optimal dose for pediatric ependymoma patients

Experimental therapy stops glioblastoma, high-grade gliomas in human cells and mouse models

Barrow research focuses on use of new technology for imaging brain tumors

Study reveals glioblastoma subtypes tend to develop in different regions of the brain

Proton therapy offers new hope to patients with inoperable tumors

OSMR gene plays key role in driving growth of glioblastoma tumors

Low-carbohydrate diet helps reduce growth of glioblastoma tumor cells in mouse models

Radiation plus chemotherapy improves survival of low-grade brain cancer patients

Radiation therapy plus PCV chemotherapy improves survival of low-grade glioma patients

Compound from unique blue-green algae could be key to next anti-cancer drug

Altered metabolism of two essential amino acids helps drive development of glioblastoma

Researchers develop metastasis-on-a-chip system to advance cancer investigation, drug discovery

Tews Laboratory uses LaVision BioTec UltraMicroscope to study molecular mechanisms of tumor invasion

DelMar's VAL-083 receives FDA orphan drug designation for treatment of medulloblastoma

Expression of BIRC3 protein associated with poor survival, recurrent disease in GBM patients

Strange Glow: New book seeks to remove mystery that surrounds radiation

Renishaw inVia to support development of nanomolecular probes in Kircher Laboratory at Memorial Sloan Kettering

Study provides critical insight into Warburg effect

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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