Cell Nucleus News and Research

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Researchers discover mechanism of gene silencing in hormone-dependent breast cancer cells

Sometimes, the silencing of a gene is as important as its activation. Nonetheless, up to now, most studies on hormone-mediated gene regulation have focused on researching the factors that influence the activation of certain genes. Little attention has been paid to gene silencing.

8 Jul 2016

Mitochondrial stress can trigger tumor-related metabolic shifts, study finds

Cancerous tumors must be fed. Their unregulated growth requires a steady stream of blood flow and nutrients. Thus, one way that researchers have tried to wipe out cancer is to target cells undergoing the metabolic shifts that enable a tumor's rapid growth.

7 Jul 2016

Regular marijuana use impacts the brain's natural response to rewards

Most people would get a little 'rush' out of the idea that they're about to win some money.

6 Jul 2016

Researchers identify non-coding RNA NEAT1 as potential drug target to combat cancer

A team of researchers led by professor Jean-Christophe Marine has identified NEAT1, a non-coding RNA, as a potential therapeutic target in the fight against cancer.

4 Jul 2016

New supplement could help reduce urge to consume high-calorie foods

Eating a type of powdered food supplement, based on a molecule produced by bacteria in the gut, reduces cravings for high-calorie foods such as chocolate, cake and pizza, a new study suggests.

1 Jul 2016

Scientists investigate molecular mechanisms that regulate STAT3 activity

Hokkaido University scientists are getting closer to understanding the function of a protein involved in vital cellular processes. This may lead to the discovery of drugs that can treat some cancers and autoimmune disorders.

1 Jul 2016

New bioinformatics tool can analyse 40,000 proteins per minute

Biology and computing have joined forces to create a piece of software that analyses mutations in proteins; these mutations are potential inducers of diseases, such as cancer.

30 Jun 2016

Researchers determine how Ki-67 protein disperses chromosomes in dividing cells

Billions of your cells divide every day. Cell division fuels growth and also replaces short-lived cells in some organs, like your skin, blood, and gut.

30 Jun 2016

Researchers reveal novel mechanism by which viral protein VII suppresses immune alarm signals

Viruses must avoid a host's immune system to establish successful infections—and scientists have discovered another tool that viruses use to frustrate host defenses.

30 Jun 2016

Tiny doses of anti-HIV drug may be effective for treating Alzheimer's disease

For a promising pathway to treating Alzheimer's patients, "aim here." That's what National Institute of Standards of Technology researchers advised collaborators hunting for molecules that, by linking to a normally occurring enzyme, rev up the brain's capacity for clearing cholesterol--a boost associated with improvements in memory and other benefits in animal studies.

29 Jun 2016

Why does appetite loss occur during illness? An interview with Prof. Conti and Prof. Francesconi

Appetite, as a word, come from the Latin appetitus, meaning "desire for.” Therefore, appetite can be defined as a pleasurable sensation or the desire to eat. This sensation is coordinated by several brain areas associated with reward processing such amygdala, hippocampus, ventral pallidum, nucleus accumbens and striatum, and others.

28 Jun 2016

Study reveals distribution of toxic arsenic in cell nuclei of plants

Toxic arsenic initially accumulates in the nuclei of plants' cells. This has been revealed by an X-ray examination of the aquatic plant rigid hornwort (Ceratophyllum demersum) using DESY's X-ray source PETRA III.

25 Jun 2016

Researchers tune into previously unknown cross talk between estrogen and progesterone receptors

One of the first clues pathologists look for in tissue from a newly diagnosed breast cancer patient is the estrogen receptor, a nuclear protein that converts hormonal messages in the bloodstream into instructions for the cell about how to behave

24 Jun 2016

Study reveals surprising diversity in single neuronal transcriptomes of the brain

A team of scientists at The Scripps Research Institute, University of California, San Diego and Illumina, Inc., has completed the first large-scale assessment of single neuronal "transcriptomes."

24 Jun 2016

Researchers reveal DNA unwrapping can happen asymmetrically to expose specific genes

The protein complex that holds strands of DNA in compact spools partially disassembles itself to help genes reveal themselves to specialized proteins and enzymes for activation, according to Rice University researchers and their colleagues.

22 Jun 2016

Scientists study fundamentals of tumour surveillance by immune system in mice models

The body's defences detect and eliminate not only pathogens but also tumour cells. Natural killer cells (NK-Cells) are specifically activated by chemical messengers, the Cytokines, to seek and destroy tumour cells.

20 Jun 2016

New research helps better understand role of TIP60 in allowing tumors to survive in low-oxygen environments

In summer 2011, University of Colorado Cancer Center investigators Joaquín Espinosa, PhD, and Matthew Galbraith, PhD, taught a summer symposium on gene expression at Cold Spring Harbor Laboratory in Long Island, New York.

17 Jun 2016

Research highlights significance of ultra-rapid brain responses to threat-related visual stimuli

An international team lead by researchers from CTB-UPM shows that the amygdala in the human brain is able to detect possible threats in the visual environment at ultra-fast time scales.

15 Jun 2016

Stimulating STING pathway to provoke life-extending immune response shows promise in AML

A protein known as STING plays a crucial role in the immune system's ability to "sense" cancer by recognizing and responding to DNA from tumor cells. Injection of compounds that activate the STING pathway directly into solid tumors in mice has been shown in prior studies to result in very potent anti-tumor immune responses.

3 Jun 2016

Lund researchers identify four genetic keys that can unlock code, reprogram skin cells

Eight days. That's how long it takes for skin cells to reprogram into red blood cells. Researchers at Lund University in Sweden, together with colleagues at Center of Regenerative Medicine in Barcelona, have successfully identified the four genetic keys that unlock the genetic code of skin cells and reprogram them to start producing red blood cells instead.

3 Jun 2016

Cell Nucleus News and Research

Researchers discover mechanism of gene silencing in hormone-dependent breast cancer cells

Mitochondrial stress can trigger tumor-related metabolic shifts, study finds

Regular marijuana use impacts the brain's natural response to rewards

Researchers identify non-coding RNA NEAT1 as potential drug target to combat cancer

New supplement could help reduce urge to consume high-calorie foods

Scientists investigate molecular mechanisms that regulate STAT3 activity

New bioinformatics tool can analyse 40,000 proteins per minute

Researchers determine how Ki-67 protein disperses chromosomes in dividing cells

Researchers reveal novel mechanism by which viral protein VII suppresses immune alarm signals

Tiny doses of anti-HIV drug may be effective for treating Alzheimer's disease

Why does appetite loss occur during illness? An interview with Prof. Conti and Prof. Francesconi

Study reveals distribution of toxic arsenic in cell nuclei of plants

Researchers tune into previously unknown cross talk between estrogen and progesterone receptors

Study reveals surprising diversity in single neuronal transcriptomes of the brain

Researchers reveal DNA unwrapping can happen asymmetrically to expose specific genes

Scientists study fundamentals of tumour surveillance by immune system in mice models

New research helps better understand role of TIP60 in allowing tumors to survive in low-oxygen environments

Research highlights significance of ultra-rapid brain responses to threat-related visual stimuli

Stimulating STING pathway to provoke life-extending immune response shows promise in AML

Lund researchers identify four genetic keys that can unlock code, reprogram skin cells

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