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Study finds new genetic clues associated with asthma in African ancestry populations

In the largest study of its kind, researchers at the University of Colorado Anschutz Medical Campus have found new clues into the parts of the human genome associated with the higher rates of asthma in those of African ancestry.

21 Feb 2019

Artificial intelligence can accurately predict prognosis of ovarian cancer patients

The artificial intelligence software, created by researchers at Imperial College London and the University of Melbourne, has been able to predict the prognosis of patients with ovarian cancer more accurately than current methods. It can also predict what treatment would be most effective for patients following diagnosis.

15 Feb 2019

Women fare worse than men following aortic heart surgery, study finds

New research says women fare worse than men following aortic heart surgery.

14 Feb 2019

New machine learning method predicts if atypical ductal hyperplasia will turn cancerous

Atypical ductal hyperplasia is a breast lesion associated with a four- to five-fold increase in the risk of breast cancer.

13 Feb 2019

When genomic sequencing fails to diagnose a rare disease

Routine sequencing has given unprecedented insight into the genetics of rare diseases, but genomics fails to diagnose up to half of patients who are tested. That's the problem German scientists tackled in a recent study in the journal Molecular & Cellular Proteomics.

11 Feb 2019

Cloning-free Nested CRISPR uses long DNA fragments for efficient gene editing

CRISPR is a technique that is revolutionizing biomedical research through high-precision genome editing. However, even though it allows the creation or correction of mutations consisting of a single or few nucleotides with relative ease, it still possesses limitations upon introducing larger fragments of DNA in the genome.

8 Feb 2019

Researchers reveal novel computational tool used to analyze genetic variation

The field of genetic sequencing has undergone a dramatic revolution over the past 20 years. In 2001 the first copy of the three billion base pairs that assemble the human genome was published.

8 Feb 2019

Simulation model to find the most optimal cancer treatment

In ten years, computers will be able to propose the most suitable cancer treatment for you. The idea is to simulate how all possible combinations of existing cancer treatments will work on your particular tumor.

6 Feb 2019

New breakthrough study can impact drug development and personalized medicine

A breakthrough for brain tumor drug development and personalized medicine published today in Nature Scientific Reports.

6 Feb 2019

Powerful immune molecule silences barrel to protect transplanted organs from rejection

A powerful immune molecule helps protect transplanted organs from rejection by putting a silencer on two other immune molecules that converge to take a direct shot at the organ, scientists report.

5 Feb 2019

Researchers call for industry standards to help improve high-throughput genomic sequencing

Researchers from the George Washington University, the U.S. Food and Drug Administration, and industry leaders published in PLOS Biology, describing a standardized communication method for researchers performing high-throughput sequencing called BioCompute.

31 Jan 2019

New approach identifies epigenetic changes in leukemia cells for patients undergoing ibrutinib treatment

Many new anti-cancer drugs inhibit proteins that are essential for the proliferation of cancer cells. One example is ibrutinib, an innovative therapy for chronic lymphocytic leukemia first approved in 2014.

29 Jan 2019

Review paper on transformative potential of precision and personalized medicine for cancer treatment

In a paper published in the September/December 2018 issue of TECHNOLOGY, a group of researchers from Rutgers University Department of Biomedicine Engineering have published a review paper on the transformative potential of precision and personalized medicine (PPM) for cancer treatment.

29 Jan 2019

Newly developed algorithms can predict and correct errors in single cell analyses

Modern technology makes it possible to sequence individual cells and to identify which genes are currently being expressed in each cell.

24 Jan 2019

Training heart cells in culture to mimic human cardiac tissue

Engineering researchers have developed a “training” device that can be used to grow cardiac tissue and measure how effectively it beats.

24 Jan 2019

Rapid resistance gene sequencing technology can hasten identification of antibiotic-resistant bacteria

Researchers at Johns Hopkins Medicine say they have added to evidence that rapid resistance gene sequencing technology can accurately speed the identification of specific antibiotic-resistant bacteria strains that sicken and kill some patients.

18 Jan 2019

New project receives €8.65 million from EU and Canada to ease genomic, health data sharing

The European Union and the Canadian government have awarded the international iReceptor Plus consortium, which is composed of more than 20 partners, €8.65 million to promote human immunological data storage, integration and controlled sharing for a wide range of clinical and scientific purposes.

16 Jan 2019