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Estrogen-responsive cells found to heighten gut pain in females

Researchers uncovered how estrogen heightens gut sensitivity in females by activating PYY-secreting L-cells, which stimulate serotonin release from EC cells. This paracrine circuit intensifies pain signaling and may explain the sex bias in conditions like IBS.

16 Jun 2025

COVID-19 triggers metabolic signatures in kids that mirror adult heart risk

Children with acute COVID-19 and MIS-C show significant disruptions in lipid metabolism, including patterns resembling adult severe COVID-19. These findings highlight potential long-term cardiovascular risks in pediatric SARS-CoV-2 cases and underscore the need for follow-up care.

16 Jun 2025

New hereditary condition impairs DNA repair and raises blood cancer risk

A new hereditary condition has been discovered that affects patients' ability to repair DNA – leaving them both at greater risk of developing blood cancer, and unable to repair some of the damage caused by chemotherapy treatments.

16 Jun 2025

‘Not accountable to anyone’: As insurers issue denials, some patients run out of options

By the time Eric Tennant was diagnosed in 2023 with a rare cancer of the bile ducts, the disease had spread to his bones. He weighed 97 pounds and wasn't expected to survive a year with stage 4 cancer.

16 Jun 2025

A revolutionary drug for extreme hunger offers clues to obesity’s complexity

Ali Foley Shenk still remembers the panic when her 10-year-old son, Dean, finished a 20-ounce box of raisins in the seconds the cupboard was left unlocked. They rushed to the emergency room, fearing a dangerous bowel impaction.

16 Jun 2025

Deep B cell depletion offers new hope for rheumatologic and musculoskeletal diseases

CD19-CAR T-cell treatment is a novel option of deep B cell depletion with promising results across different rheumatologic and musculoskeletal diseases (RMD).

15 Jun 2025

WHO warns of ORVO as outbreaks surge and health risks rise

Oropouche virus poses a growing public health risk, with recent outbreaks in Brazil and Cuba. The WHO report calls for urgent global preparedness measures.

13 Jun 2025

New nanopore sequencing assay advances fragile X syndrome carrier screening

Researchers have developed an innovative new nanopore sequencing assay to identify carriers of fragile X syndrome (FXS), the leading cause of monogenic autism spectrum disorder and inherited intellectual disabilities.

12 Jun 2025

Chronic hyponatremia causes anxiety-like behaviors by disrupting brain chemistry

Hyponatremia, or low blood sodium concentration, is typically viewed as a symptomless condition-until recently.

12 Jun 2025

Exercise and omega-3 reduce oral inflammation in animal study

A study published in the journal Scientific Reports indicates that physical exercise combined with omega-3 supplementation considerably improves the immune response and reduces the severity of chronic apical periodontitis.

11 Jun 2025

New hypothesis links caffeine to lower risk of sudden infant death syndrome

After decades of stalled national progress in reducing the rate of Sudden Unexpected Infant Death (SUID), a category of infant mortality that includes sudden infant death syndrome (SIDS), researchers at Rutgers Health have proposed an unexpected solution: Caffeine might protect babies by preventing dangerous drops in oxygen that may trigger deaths.

11 Jun 2025

Weekly risperidone capsule delivers consistent drug levels for schizophrenia patients

For many patients with schizophrenia, other psychiatric illnesses, or diseases such as hypertension and asthma, it can be difficult to take their medicine every day.

10 Jun 2025

Early signs of breastfeeding failures after premature birth

A study on breastfeeding after premature birth identifies key factors affecting milk composition and volume, emphasizing the need for early support for mothers.

10 Jun 2025

Smartwatch alerts retired nurse to heart injury, prompting life-saving hospital care

A smartwatch detected abnormal ECG changes in a 76-year-old woman experiencing chest pain following emotional stress. Hospital investigations confirmed takotsubo (stress) cardiomyopathy, highlighting the potential and limitations of wearable health technology in acute cardiac care.

10 Jun 2025

Lynch syndrome testing often missed in womb cancer patients

Patients with womb cancer are not being tested for a genetic condition that increases their chance of developing further cancers, a study has found.

9 Jun 2025

Study offers new insights into how the body clears dead cells during stress

A new study from The University of Texas at Arlington details a novel strategy for how the body clears out dead cells during stress, revealing unexpected roles for well-known stress-response genes-a discovery that could help scientists better understand diseases affecting the immune system, brain and metabolism.

9 Jun 2025

New COVID variant NB.1.8.1 spreads across continents amid calls for vigilance

The Global Virus Network (GVN) is closely monitoring the emergence of a newly identified SARS-CoV-2 variant, NB.1.8.1, a sublineage of the Omicron family. This variant was first identified in January 2025 and has rapidly spread across Asia and into other regions, including parts of the United States.

6 Jun 2025

Nicotinamide riboside shows promise in treating Werner syndrome symptoms

Werner syndrome (WS) is a rare genetic disorder that causes premature aging and serious complications. In the first clinical trial of its kind, researchers from Japan with the company Niagen Bioscience, investigated the effects of nicotinamide riboside (NR), a vitamin B3 derivative, in patients with WS.

5 Jun 2025

Wayne State researchers investigate effects of fentanyl use during pregnancy

A new National Institutes of Health (NIH) grant will aid Wayne State University researchers in measuring the effects of fentanyl during pregnancy on maternal behaviors and offspring at birth through early development.

5 Jun 2025

Personalized exercise and coaching could improve health of people with neuromuscular diseases

While many people with neuromuscular diseases currently face a future without a cure, a new study finds that a personalized exercise and coaching program could improve their fitness and overall health.

4 Jun 2025