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UM SOM study identifies key Zika proteins as likely suspects for damage

Until it burst onto the scene earlier this year, Zika was an obscure, little-known virus. As a result, scientists know little about how it works.

3 Jan 2017

C elegans could be powerful model for understanding how nervous systems produce behaviors

The human brain, the most complex object in the universe, has 86 billion neurons with trillions of yet-unmapped connections.

27 Dec 2016

Contact dermatitis or contact eczema?

There is allergic contact dermatitis, which is mediated through an immune mechanism, this means that the person is specifically allergic to what they have come in to contact with their skin. Their body has had to go through a process whereby they have...

21 Dec 2016

TUM researchers discover vital mechanism in the body's defenses against fungal infections

Fungal infections are a serious health risk. They can be harmful especially to patients whose immune system is compromised through illness or chemotherapy.

19 Dec 2016

Researchers identify attractive drug candidate to target glioma tumors

In a paper published today in Cancer Research, researchers: 1) identify a biomarker enzyme associated with aggressive glioma brain tumors, 2) reveal the regulatory mechanism for that enzyme, and 3) demonstrate potent efficacy, using a mouse model of glioma, for a small molecule inhibitor they have developed.

16 Dec 2016

Tufts scientists discover reason for incidence of genetic error that causes many disorders

Tufts University researchers have discovered a possible explanation for the occurrence of a genetic error that causes over a dozen neuromuscular and neurodegenerative disorders, including Huntington's disease, myotonic dystrophy and forms of spinocerebellar ataxia.

6 Dec 2016

New drug receives FDA approval to reduce risk of cardiovascular death in adults with diabetes

The U.S. Food and Drug Administration today approved a new indication for Jardiance (empagliflozin) to reduce the risk of cardiovascular death in adult patients with type 2 diabetes mellitus and cardiovascular disease.

2 Dec 2016

TUM scientists uncover molecular mechanisms of inhibitors that can selectively thwart immunoproteasome

The immunoproteasome dismantles proteins and the resulting fragments are displayed on the surface of cells. This helps the immune system to recognize abnormal cells. However, in chronic inflammations and autoimmune diseases this “information channel” is overactive.

29 Nov 2016

FASEB announces winners of 2016 BioArt competition

The Federation of American Societies for Experimental Biology is pleased to announce the winners of the fifth annual BioArt competition.

22 Nov 2016

Natural compound slows typical signs of aging in mice

Much of human health hinges on how well the body manufactures and uses energy. For reasons that remain unclear, cells' ability to produce energy declines with age, prompting scientists to suspect that the steady loss of efficiency in the body's energy supply chain is a key driver of the aging process.

27 Oct 2016

MTPConnect to provide $7.4 million funding for 14 national projects in medtech, biotech and pharmaceutical sector

MTPConnect - the Medical Technologies and Pharmaceuticals Industry Growth Centre - today announced it will provide $7.4 million of funding over two years for 14 national projects in the medtech, biotech and pharmaceutical (MTP) sector.

25 Oct 2016

Fission yeast could help discover novel cancer drugs

Cancer is a notoriously difficult disease to treat. Not only do a wide variety of cancers exist, requiring specialized treatments for each type, but cancer cells within an individual can morph and render previously potent therapeutics ineffective.

24 Oct 2016

UA study questions safety and efficacy of selenium in reducing risk of colorectal cancer

A 12-year study led by a team of University of Arizona Cancer Center researchers is bringing into question the safety and efficacy of selenium, a popular nutritional supplement touted to combat and reduce the risk of colorectal cancer.

14 Oct 2016

Prion proteins can drive emergence of new traits and adaptive opportunities

Prion proteins, best known as the agents of deadly brain disorders like mad cow disease, can help yeast survive hard times and pass the advantageous traits down to their offspring, according to a new study by researchers at the Stanford University School of Medicine.

4 Oct 2016

Novel bifunctional dimers show promise in preventing Parkinson's disease

A team of researchers from the University of Saskatchewan has developed two caffeine-based chemical compounds that show promise in preventing the ravages of Parkinson's disease.

30 Sep 2016

FDA approves new biosimilar for multiple inflammatory diseases

The U.S. Food and Drug Administration today approved Amjevita (adalimumab-atto) as a biosimilar to Humira (adalimumab) for multiple inflammatory diseases.

23 Sep 2016

New global map shines light on genetic roots of diseases

A global genetic interaction map is revolutionizing how genes are being studied. A new study, involving University of Minnesota researchers, is no longer looking at genes as loners, but instead as a social network of the body, interacting in groups. The new approach may ultimately change our understanding of the genetic roots of diseases.

23 Sep 2016

Genome-wide studies reveal evolutionary conserved enzyme facilitates DNA replication

Genome-wide studies of fission yeast (Schizosaccharomyces pombe) suggest that the evolutionary conserved enzyme Pfh1 helicase facilitates DNA synthesis by tracking along with the replication apparatus, promoting intact DNA synthesis at hard-to-replicate sites and consequently suppressing DNA damage. The findings are published in PLOS Genetics.

12 Sep 2016

Montreal-based researchers get closer to achieving healthy longevity

Hearing loss, brittle bones, sagging skin, a deteriorating mind: these are just some of the issues associated with growing old.

7 Sep 2016

Fungal communities in chronic wounds can be linked to poor outcomes and slow healing

Researchers in Pennsylvania and Iowa have discovered that fungal communities found in chronic wounds can form mixed bacterial-fungal biofilms and can be associated with poor outcomes and longer healing times.

6 Sep 2016