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Discovery of protein that plays a key role in the recycling of iron from blood

Scientists working in the only lab at MIT doing hematology research have uncovered a protein that plays a key role in the recycling of iron from blood. Their work, described in the October 11 Journal of Clinical Investigation, could lead to new therapies for certain inherited blood disorders such as beta-thalassemia, a condition that causes chronic anemia.

12 Oct 2007

Compound called apolipoprotein B in blood better at predicting coronary heart disease in Chinese people

Scientists report in the November 2007 issue of the Journal of Lipid Research that the concentration of a compound called apolipoprotein B in the blood is better at predicting whether Chinese have coronary heart disease – in which fatty deposits clog arteries that supply blood and oxygen to the heart – than other substances such as blood cholesterol levels.

12 Oct 2007

Injectable macro-porous material, for the treatment of bone diseases such as osteoporosis

Researchers of the BIOMAT (Biomaterials Centre) of the Universidad de La Habana have obtained an injectable macro-porous material, useful for the treatment of degenerative diseases such as osteoporosis, to refill bone cavities and in stomatology.

10 Oct 2007

Injectable antibody reverses cognitive deficits in mice

A special protein can be injected into the body to reverse learning problems in mice that have an animal version of Alzheimer's disease, Saint Louis University researchers have found.

9 Oct 2007

Potential new treatment for Huntington's disease found

MassGeneral Institute for Neurodegererative Disorders (MIND) researchers have identified a compound that may lead to a treatment that could protect against the effects of Huntington's Disease (HD).

9 Oct 2007

Dual action anthrax vaccine-antitoxin combination developed

The immune response generated in rats by the new agent protects against lethal toxin exposure after only one injection, and is faster and stronger than any currently available vaccine.

8 Oct 2007

Researchers tackle phantom sounds of tinnitus

For the more than 50 million Americans who experience the phantom sounds of tinnitus -- ringing in the ears that can range from annoying to debilitating -- certain well-trained rats may be their best hope for finding relief.

8 Oct 2007

Researchers create modular, multi-functional drug delivery system

There are two aspects to creating an effective drug: finding a chemical compound that has the desired biological effect and minimal side-effects and then delivering it to the right place in the body for it to do its job.

8 Oct 2007

Creatine in addition to exercise enhances strength in older adults

Lower muscle mass and an increase in body fat are common consequences of growing older.

3 Oct 2007

Judge acquits Canadian doctors, U.S. drug company in tainted blood case

A Canadian judge on Monday acquitted New Jersey-based Armour Pharmaceutical Company and four Canadian doctors -- including the former medical director of the Canadian Red Cross and two government officials -- of charges related to blood products contaminated with HIV and hepatitis C, the New York Times reports (Austen, New York Times, 10/2).

2 Oct 2007

Early stage drug shows promise against cancer cells from young patients

A new drug has shown promising pre-clinical activity against cells from several types of children's cancers, scientists reveal at the National Cancer Research Institute Conference in Birmingham today (Tuesday).

2 Oct 2007

Daisy compound used to attack cancer stem cells

A new, easily ingested form of a compound that has already shown it can attack the roots of leukemia in laboratory studies is moving into human clinical trials, according to a new article by University of Rochester investigators in the journal, Blood.

2 Oct 2007

Mechanism behind nicotine dependency revealed

The research is being published the week of October 1, 2007, in an advance, online issue of the journal Proceedings of the National Academy of Sciences (PNAS).

2 Oct 2007

Tree bark compound gambogic amide stimulates growth, survival of brain cells

Researchers have identified a compound in tree bark that mimics the chemical reactions of a naturally occurring molecule in the brain responsible for stimulating neuronal cell signaling.

2 Oct 2007

Potential new therapy for uveitis

An inflammatory eye condition that is one of the world's leading causes of blindness could be treated much more effectively and easily thanks to a new discovery here.

29 Sep 2007

Male contraception

For decades, pundits have predicted new contraceptives for men within the next 5 to 10 years.

29 Sep 2007

Breakthrough in the development of nanometer X-ray resolution

A team of researchers at the U.S. Department of Energy's Brookhaven National Laboratory have overcome a major obstacle for using refractive lenses to focus x-rays.

29 Sep 2007

Survival data presented from phase II study of hormone-resistant prostate cancer patients

The results from the randomized, double -blind, placebo -controlled, Phase II EPOC (Endothelin A Proof Of Concept) Study of ZD4054 - a specific endothelin A (ETA) receptor antagonist – were delivered at the 14th European Congress of Clinical Oncology (ECCO, 23-27 September, Barcelona).

26 Sep 2007

New AstraZeneca compound shows promoise for hormone resistant prostate cancer patients with bone metastases

New Phase II data suggests that ZD4054, a novel compound in development for the treatment of men with Hormone Resistant Prostate Cancer (HRPC), could offer a promising improvement in overall survival in men with metastatic HRPC who were asymptomatic or mildly symptomatic for pain.

26 Sep 2007

FDA fast tracks PI-88 for the treatment of post resection liver cancer

Progen Pharmaceuticals Limited has announced that its investigational anti-cancer drug PI-88 has been awarded Fast Track status by the U.S. Food and Drug Administration (FDA).

25 Sep 2007