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Study reveals risk factors for mortality in diabetic patients discharged from hospital

When patients are discharged from Hospital those with diabetes are at an increased risk of readmission and mortality, there are guidelines for discharging patients with diabetes to reduce these risks, however researchers from the Institute of Digital Healthcare at WMG, University of Warwick and Warwick Medical School have identified known risk factors for mortality in adult patients discharged from hospital with diabetes.

2 Sep 2020

Novel technique to detect the fungus responsible for causing severe pneumonia

Research staff of the University of Valencia and the Foundation for the Promotion of Health and Biomedical Research of the Valencian Community, among other institutions, have developed a very sensitive and fast in-vitro method for the diagnosis of infection by Pneumocystis jirovecii, a fungus that causes severe pneumonia.

2 Sep 2020

Exponential rise in COVID-19 hospitalization risk with age due to waning T cell immunity

The age-related increase in the risk of severe disease and death from COVID-19 mirrors earlier patterns seen with infections. Such trends may help understand the mechanisms underlying the clinical feature. A recent study published in the preprint server medRxiv* in August 2020 shows the effect of age and sex on COVID-19 hospitalization rates in the USA and helps understand how immune function is involved in this pandemic.

2 Sep 2020

ACE2/TMPRSS2 not expressed in pancreatic islet endocrine cells

A new study by researchers at the Vanderbilt University Medical Center and the University of Pennsylvania Perelman School of Medicine and published on the preprint server bioRxiv* in August 2020 reports that both key enzymes that are required for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) entry into the human host cell are lacking in the beta cells of the pancreatic islet. This rules out the direct injury hypothesis for impaired glucose control in patients with COVID-19 disease.

1 Sep 2020

Negligible ACE2 expression in human beta-cells

Now, a new study published on the preprint server bioRxiv reports that even though the fatality rate is significantly higher in diabetics, there is no evidence that this is due to direct viral infection of pancreatic beta cells, which produce the key hormone in glucose homeostasis, namely insulin.

1 Sep 2020

Mount Sinai hospitals win top quality achievement awards for stroke and cardiac care

Seven Mount Sinai Health System hospitals have received top quality achievement awards from the American Heart Association for ensuring that patients with stroke, heart failure, and severe heart attacks receive the most appropriate and safest treatment for the best possible outcomes.

1 Sep 2020

Restrictive blood transfusion strategy has no negative impact on anemic heart attack patients

Restricting blood transfusion in anemic heart attack patients to those with very low hemoglobin levels saves blood with no negative impact on clinical outcomes.

1 Sep 2020

COVID-19 testing and reporting needs improving in United States prisons

Researchers at the University of North Carolina at Chapel Hill and Cornell University have conducted a study showing that many states across the US are not reporting fully on the number of people being tested for coronavirus disease 2019 (COVID-19) in prisons, with some also not reporting on cases of fatalities.

1 Sep 2020

Common heart drugs are safe for patients hospitalized with COVID-19

Heart patients hospitalized with COVID-19 can safely continue taking angiotensin-converting enzyme (ACE) inhibitors and angiotensin receptor blockers (ARBs), according to the BRACE CORONA trial presented in a Hot Line session today at ESC Congress 2020.

1 Sep 2020

Human antibody response to SARS-CoV-2

A new study published on the preprint server medRxiv* in August 2020 reports on the human antibody response in severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection, which is key to developing vaccines and managing the pandemic, as well as designing and executing serologic testing and interpreting their results.

1 Sep 2020

$Sacubitril/valsartan therapy may reduce hospitalization in heart patients with preserved ejection fraction$

Sacubitril/valsartan therapy may reduce hospitalization in heart patients with preserved ejection fraction

Sacubitril/valsartan reduces NT-proBNP, a biomarker predictive of long-term clinical outcomes in heart failure, but does not improve functional capacity compared to individualized background therapy in patients with heart failure with preserved ejection fraction

1 Sep 2020

Eating ultraprocessed food shortens your telomeres

Now, a new study titled, "Ultra-processed food consumption and the risk of short telomeres in an elderly population of the Seguimiento Universidad de Navarra (SUN) Project," is being presented at this year's European and International Conference on Obesity (ECOICO 2020), held online this year (1-4 September).

31 Aug 2020

COVID-19 patients may experience long-term cardiovascular complications

Researchers at the University of Washington in Seattle have conducted a study suggesting that infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) can directly infect heart tissue and contribute to whole-organ cardiac dysfunction.

31 Aug 2020

SGLT2 inhibitors can slow CKD progression

850 million people worldwide are affected by chronic kidney disease (CKD) - a worrying figure, and one that continues to rise.

31 Aug 2020

Hestia criteria, sPESI score can be used to select pulmonary embolism patients for outpatient care

Patients with acute pulmonary embolism can be selected for home management using the sPESI score or the Hestia criteria, according to results of the HOME-PE trial presented in a Hot Line session today at ESC Congress 2020.

31 Aug 2020

Study shows best antiplatelet treatment after transcatheter aortic valve implantation

The POPular TAVI trial has challenged current guideline recommendations on antiplatelet treatment after transcatheter aortic valve implantation (TAVI) in patients not taking oral anticoagulation. The findings are presented in a Hot Line session today at ESC Congress 2020.

31 Aug 2020

Mortality News and Research

Study reveals risk factors for mortality in diabetic patients discharged from hospital

Novel technique to detect the fungus responsible for causing severe pneumonia

Exponential rise in COVID-19 hospitalization risk with age due to waning T cell immunity

ACE2/TMPRSS2 not expressed in pancreatic islet endocrine cells

Negligible ACE2 expression in human beta-cells

Mount Sinai hospitals win top quality achievement awards for stroke and cardiac care

Restrictive blood transfusion strategy has no negative impact on anemic heart attack patients

COVID-19 testing and reporting needs improving in United States prisons

Common heart drugs are safe for patients hospitalized with COVID-19

Human antibody response to SARS-CoV-2

Sacubitril/valsartan therapy may reduce hospitalization in heart patients with preserved ejection fraction

Eating ultraprocessed food shortens your telomeres

COVID-19 patients may experience long-term cardiovascular complications

SGLT2 inhibitors can slow CKD progression

Hestia criteria, sPESI score can be used to select pulmonary embolism patients for outpatient care

Study shows best antiplatelet treatment after transcatheter aortic valve implantation

DAPA-CKD trial shows dapagliflozin reduces risk of chronic kidney disease

WHO advises healthcare professionals to ensure correct administration of chlorhexidine

Study: Preventive medications reduce risk of heart attacks in diabetic patients

Serum protein shows therapeutic value against severe COVID-19-like features in mouse model

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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