Protein News and Research

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Proteins are complex molecules that are made up of amino acids. They can be found in every cell in the body, and carry out vital processes that keep human beings alive. Mutations in proteins can lead to a multitude of diseases, the most common being cancer.

Study paves way for developing effective ASO therapies for brain diseases with fewer side effects

A promising therapy for a range of brain diseases involves antisense oligonucleotides (ASOs) - specialized molecules that can modulate RNA and alter protein production - directly injected into the cerebrospinal fluid, in the space around the brain and spinal cord.

14 Mar 2023

XBP1s plays a key role in controlling IL-15-mediated NK cell survival, study shows

A new study published in Science Immunology points to a promising therapeutic approach for future cancer treatments based on natural killer cells (NK), which are immune cells that bind to tumor cells and destroy them.

14 Mar 2023

Correcting abnormalities in solid tumor's blood vessels can improve efficacy of CAR-T cell therapy

A type of immune therapy called chimeric antigen receptor (CAR)-T cell therapy has revolutionized the treatment of multiple types of blood cancers but has shown limited efficacy against glioblastoma - the deadliest type of primary brain cancer - and other solid tumors.

14 Mar 2023

Spike-induced humoral immunity and its association with antibody-dependent cellular cytotoxicity potency

A new study aimed to analyze the qualitative and quantitative impact of S-induced humoral immunity along with its ADCC capability in individuals who received a vaccination, recovered from an infection, or both.

14 Mar 2023

Understanding how cells adjust in real time to withstand stresses on our health

Every minute of every day, our body adapts to meet the needs of each moment. When we binge on carbs, exercise, or become sick, chemical reactions inside our cells switch on, slow down, or shift strategy so that we have the energy and strength we need.

14 Mar 2023

Study suggests mRNA vaccines decouple SARS-CoV-2 immunity from autoantibody responses observed during acute COVID-19

Researchers investigated whether mRNA technology-based COVID-19 vaccines promote the development of autoantibodies.

14 Mar 2023

Study shows SARS-CoV-2 causes DNA damage and elicits an altered DNA damage response

Researchers assessed the association between SARS-CoV-2 infection and DNA damage and cellular senescence.

14 Mar 2023

Researchers identify the mSWI/SNF chromatin remodeling complex as a host-directed drug target for SARS-CoV-2 infection

Researchers showed that mammalian SWItch/Sucrose Non-Fermentable (mSWI/SNF) chromatin remodeling complexes represent a potential class of host-directed broad-acting SARS-CoV-2 therapeutic targets.

14 Mar 2023

The development of the pediatric oral resistome and its role in dental caries

Researchers performed a genomic investigation of oral resistome development, i.e., of genes that confer antimicrobial resistance.

14 Mar 2023

Oral host responses to SARS-CoV-2 predict progression of COVID-19

In a recent study posted to the medRxiv* preprint server, researchers at the University of North Carolina and the National Institutes of Health determined the associations between oral severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), oral antibodies against SARS-CoV-2, and coronavirus disease 2019 (COVID-19) symptoms.

14 Mar 2023

Hypothalamic inflammation and obesity, study suggests a pathological mechanism

In a recent review published in the European Journal of Endocrinology, researchers discussed current research on the relationship between human obesity and inflammation of the hypothalamus.

14 Mar 2023

Revamping lifestyle can bolster brain health and stave off neurocognitive decline

In a recent article published in the journal Cureus, researchers at Loma Linda University Medical Center and the University of California Irvine reviewed the impact of applying the six pillars of lifestyle medicine — stress management, plant-based nutrition, avoidance of risky substances, physical activity, social connections, and restorative sleep — on neurocognitive decline and dementia.

14 Mar 2023

Is green leaf biomass a viable and sustainable source of protein?

In a recent study published in the journal Nutrients, researchers at North Carolina State University reviewed studies on underutilized sources of plant proteins and discussed strategies to enhance yields, extract nutrients and influence the demand and acceptance of new protein sources, especially green leaf biomass.

14 Mar 2023

Bispecific antibody shows improved efficacy against SARS-CoV-2 variants

Researchers from The University of Texas MD Anderson Cancer Center have developed fully human bispecific antibodies, as revealed in a recent study. These antibodies can bind to two distinct epitopes of the receptor binding domain (RBD) of the SARS-CoV-2 spike protein and have demonstrated the ability to neutralize various strains of the virus, including the Omicron variant.

14 Mar 2023

Protein News and Research

Further Reading

Study paves way for developing effective ASO therapies for brain diseases with fewer side effects

XBP1s plays a key role in controlling IL-15-mediated NK cell survival, study shows

Correcting abnormalities in solid tumor's blood vessels can improve efficacy of CAR-T cell therapy

Spike-induced humoral immunity and its association with antibody-dependent cellular cytotoxicity potency

Understanding how cells adjust in real time to withstand stresses on our health

Study suggests mRNA vaccines decouple SARS-CoV-2 immunity from autoantibody responses observed during acute COVID-19

Study shows SARS-CoV-2 causes DNA damage and elicits an altered DNA damage response

Researchers identify the mSWI/SNF chromatin remodeling complex as a host-directed drug target for SARS-CoV-2 infection

The development of the pediatric oral resistome and its role in dental caries

Oral host responses to SARS-CoV-2 predict progression of COVID-19

Hypothalamic inflammation and obesity, study suggests a pathological mechanism

Revamping lifestyle can bolster brain health and stave off neurocognitive decline

Is green leaf biomass a viable and sustainable source of protein?

Bispecific antibody shows improved efficacy against SARS-CoV-2 variants

Consuming low-insulin-stimulating bread significantly reduces body weight

Hyperinflammation triggers long COVID headaches

AI-assisted analysis helps find new targets for CAR-T cell therapy against acute myeloid leukemia

Cholesterol-lowering drugs show potential to reduce heart disease in sleep apnea patients

Schizophrenia risk conferred by rare damaging genetic variants is conserved across ethnicities

TbID-based proteomic profiling in meiotic cells helps identify proximate proteins in A. thaliana

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