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The sympathetic nervous system can modulate action of defense cells in autoimmune disease

The results of a study conducted in Brazil suggest that the sympathetic nervous system - the part of the autonomous nervous system that controls responses to danger or stress - can modulate the action of defense cells in patients with autoimmune diseases.

16 Dec 2019

Novel and targeted cellular product causes cell death in non-Hodgkin lymphoma models

Investigators at Rutgers Cancer Institute of New Jersey have found that a treatment based on a novel cellular product programmed to deliver an overabundance of chimeric antigen receptor causes cell death in non-Hodgkin lymphoma models that are sensitive or resistant to standard therapies.

16 Dec 2019

New tool gives more reliable and precise results in cancer research

Every cell contains a vast number of proteins, each of which has a specific function, for example as a receptor for another molecule or an enzyme that catalyzes chemical reactions.

16 Dec 2019

Study unveils new layers of mystery about visual memory, amblyopia

In decades of studying how neural circuits in the brain's visual cortex adapt to experience, MIT Professor Mark Bear's lab has followed the science wherever it has led, yielding the discovery of cellular mechanisms serving visual recognition memory, in which the brain learns what sights are familiar so it can focus on what's new, and of a potential therapy for amblyopia, a disorder where children born with disrupted vision in one eye can lose visual acuity there permanently without intervention.

14 Dec 2019

Finding non-invasive nuclear medicine technique to predict effectiveness of therapy for tumors

Researchers have taken a critical step toward developing a non-invasive nuclear medicine technique that can predict the effectiveness of therapy for cancerous tumors, allowing for personalized, precision treatment.

13 Dec 2019

Patient-reported outcomes linked to aromatase inhibitor adherence

If you want to predict which breast cancer patients will most likely stop taking aromatase inhibitors, check out their own responses to the health questions patients commonly answer in cancer clinical trials, according to research findings to be presented Friday, Dec. 13 at the San Antonio Breast Cancer Symposium.

13 Dec 2019

Scientists develop new method for targeted drug delivery to cancer cells

A team of scientists from Peter the Great St.Petersburg Polytechnic University together with their colleagues developed a method of targeted drug delivery to cancer cells.

13 Dec 2019

New strategy could prevent side effects of targeted cancer treatment

Targeted, highly effective cancer treatments often produce debilitating side effects. This is the case with one commonly used therapy which works by blocking the epidermal growth factor receptor, a protein that stimulates cell proliferation.

13 Dec 2019

10-year results from clinical trial of extended letrozole therapy for women with HR+ breast cancer

In the updated results from NRG Oncology/NSABP B-42 trial through 10 years of observation, extending letrozole therapy for additional five years after five years of adjuvant endocrine therapy resulted in a statistically significant improvement in the 10-year disease-free survival (DFS) of postmenopausal women with hormone-receptor-positive breast cancer.

12 Dec 2019

Discovery of novel mechanism by which certain breast cancers can metastasize

Researchers from the Baylor College of Medicine and Harvard Medical School have found a novel mechanism to explain the resistance of certain breast cancers that spread in the major organs of the body. They hope that this would help develop new therapeutic strategies to treat the cancer.

12 Dec 2019

New drug combo promises help for triple negative breast cancer patients

A new preclinical study on triple negative breast cancer (TNBC) reports that an experimental polo-like kinase 1 (PLK1) inhibitor shrank tumor four times more powerfully when used along with standard drugs than alone. The study, reported in the journal PLOS ONE, opens up a new door of opportunity for patients with this disease.

11 Dec 2019

Help for teenagers who want to quit smoking

A new study published in the journal JAMA Pediatricsreports on the use of varenicline, a drug that helps smokers quit. The study is unique in that it targeted teenagers who wanted to quit. While confirming the low overall efficacy of the drug, it shows that it may perhaps help teenage smokers to quit faster and to stay smoke-free longer.

11 Dec 2019

Treatment combination improves survival in advanced HER2-positive breast cancer patients

Researchers from The University of Texas MD Anderson Cancer Center today reported study results showing the addition of tucatinib to capecitabine (Xeloda) and trastuzumab (Herceptin) significantly improved progression-free survival (PFS) and overall survival (OS) in patients with advanced HER2-positive breast cancer, with and without brain metastasis according to results of the HER2CLIMB clinical trial.

11 Dec 2019

FDA checks metformin drugs for potentially carcinogenic substance

The FDA is checking metformin medications used to treat diabetes for a potential carcinogen, N-nitrosodimethylamine (NDMA).

11 Dec 2019

Combination regimen shows promising results in preclinical models of triple negative breast cancer

Tumor volume in a preclinical model of triple negative breast cancer (TNBC) was reduced four times more when an experimental polo-like kinase 1 (PLK1) inhibitor was combined with a standard-of-care chemotherapeutic agent than when the agent was used alone.

10 Dec 2019

New study uncovers the genetic basis of memory

New research has uncovered the genetic basis for different functions of memory.

10 Dec 2019

Risk of specific genetic translocation is higher in patients of African ancestry, shows study

Multiple myeloma is a plasma cell cancer that is more common in patients of African American descent than of European American descent.

10 Dec 2019

Relapsed mantle cell lymphoma patients may benefit from CAR T-cell therapy

A one-year follow-up study led by The University of Texas MD Anderson Cancer Center revealed a majority of patients with mantle cell lymphoma resistant to prior therapies may benefit from treatment with CD19-targeting chimeric antigen receptor (CAR) T-cell therapy.

9 Dec 2019

Penn researchers receive nearly $5 million to reduce opioid cravings

Opioid overdoses take the lives of tens of thousands of Americans annually. Two researchers from Penn State College of Medicine have received nearly $5 million from the National Institutes of Health to study whether an already-approved drug can be used to reduce cravings and prevent relapse in those struggling with opioid addiction.

9 Dec 2019

Small, thin metal mesh loaded with T cells shrinks tumors in ovarian cancer models

New findings published Dec. 9 in Nature Biomedical Engineering from scientists at Fred Hutchinson Cancer Research Center show for the first time that a piece of small, thin metal mesh loaded with cancer-fighting immune cells shrinks tumors in preclinical models of ovarian cancer.

9 Dec 2019

Receptor News and Research

The sympathetic nervous system can modulate action of defense cells in autoimmune disease

Novel and targeted cellular product causes cell death in non-Hodgkin lymphoma models

New tool gives more reliable and precise results in cancer research

Study unveils new layers of mystery about visual memory, amblyopia

Finding non-invasive nuclear medicine technique to predict effectiveness of therapy for tumors

Patient-reported outcomes linked to aromatase inhibitor adherence

Scientists develop new method for targeted drug delivery to cancer cells

New strategy could prevent side effects of targeted cancer treatment

10-year results from clinical trial of extended letrozole therapy for women with HR+ breast cancer

Discovery of novel mechanism by which certain breast cancers can metastasize

New drug combo promises help for triple negative breast cancer patients

Help for teenagers who want to quit smoking

Treatment combination improves survival in advanced HER2-positive breast cancer patients

FDA checks metformin drugs for potentially carcinogenic substance

Combination regimen shows promising results in preclinical models of triple negative breast cancer

New study uncovers the genetic basis of memory

Risk of specific genetic translocation is higher in patients of African ancestry, shows study

Relapsed mantle cell lymphoma patients may benefit from CAR T-cell therapy

Penn researchers receive nearly $5 million to reduce opioid cravings

Small, thin metal mesh loaded with T cells shrinks tumors in ovarian cancer models

Industry Focus eBook - Analytical Chemistry (2nd Edition) eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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