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Newly developed light-activated tool could pave way for new generation of anti-diabetic drugs

Researchers have developed a light-activated tool to show how drugs need to be adapted to combat type 2 diabetes.

12 Apr 2016

BMPR2 mutations affect outcomes of PAH patients

Mutations in the bone morphogenetic protein receptor type II gene affect not only the risk of developing pulmonary arterial hypertension but also the severity and outcomes of the disease, shows a meta-analysis of individual patient data.

12 Apr 2016

Flexible ramp scripting interface added for BioScope Resolve BioAFM

At the 7th AFM BioMed Conference, Bruker’s Nano Surfaces Division today announced the release of RampScript™, which provides extensive new scripting capabilities for the BioScope Resolve® BioAFM. BioScope Resolve has set new standards for highest resolution AFM imaging with the first ever images of microvilli on live cells and by routinely resolving submolecular structures, such as the major and minor groove of DNA, while operating on an inverted microscope.

From Bruker Nano Surfaces and Metrology 11 Apr 2016

AstraZeneca, MedImmune to present new clinical trial and scientific data on lung cancer treatments at ELCC 2016

AstraZeneca and its global biologics research and development arm, MedImmune, will report new clinical trial and scientific data from their industry-leading lung cancer franchise of marketed and pipeline medicines at the European Lung Cancer Conference in Geneva, Switzerland, 13 -16 April 2016.

11 Apr 2016

Metabolic pathway activates cell signaling protein to promote breast cancer metastasis

A metabolic pathway that is up-regulated in certain breast cancers promotes the disease's progression by activating a cell signaling protein called Arf6, according to a paper published in the Journal of Cell Biology.

7 Apr 2016

Ludwig, CRI launch Phase 1/2 trial of combination immunotherapy for advanced ovarian cancer

Ludwig Cancer Research and the Cancer Research Institute have launched a Phase 1/2 clinical trial of combination immunotherapy for advanced ovarian cancer. The international, multicenter trial is led by George Coukos, director of the Ludwig Institute for Cancer Research, Lausanne and Brad Monk, director of Gynecologic Oncology at St. Joseph's Hospital and Medical Center.

7 Apr 2016

Immune cell with 'Superman' power could lead to novel therapies for type 1 diabetes

A new study led by scientists at The Scripps Research Institute (TSRI) reveals a previously unknown type of immune cell. The discovery opens new avenues in the effort to develop novel therapies for autoimmune diseases such as type 1 diabetes.

6 Apr 2016

Study explores two new antibodies believed to cause myasthenia gravis

A study of patients from across the nation with myasthenia gravis is helping determine the incidence of two new antibodies believed to cause the disease, and whether these patients need different treatment strategies.

6 Apr 2016

New study shows link between FZD7 protein and breast cancer development

A new study shows that Frizzled7 (FZD7), a protein present on human breast epithelial cells and a component of the Wnt signaling pathway is uniquely controlled by the Notch signaling pathway, both of which play key roles in mammary gland formation and breast cancer development.

6 Apr 2016

Magnesium could be safe, cost-effective therapeutic intervention for genetic coagulation disorder

An international team of scientists was able to demonstrate in mouse and patient studies, how magnesium affects the production of blood platelets and that the TRPM7 channel function plays a key role in this process. Scientists of the Rudolf Virchow Center and the Hospital of the University of Würzburg were primarily involved in this study. Their results were published in the current journal "Nature Communications".

4 Apr 2016

Researchers uncover vital clues of how the brain erases long term memories

Vital clues about how the brain erases long term memories have been uncovered by researchers. The study in rats reveals how forgetting can be the result of an active deletion process rather than a failure to remember.

2 Apr 2016

Purdue University-led researchers determine structure of Zika virus

A team led by Purdue University researchers is the first to determine the structure of the Zika virus, which reveals insights critical to the development of effective antiviral treatments and vaccines.

1 Apr 2016

Naltrexone injections could reduce risk of relapse among opioid dependent individuals

In a multicenter, randomized clinical trial, ex-prisoners who received six monthly injections of naltrexone--a long-acting medication that blocks opioid receptors in the brain--were significantly less likely to resume opioid use than those who received counseling and referrals to community treatment centers without naltrexone.

31 Mar 2016

LMU-led researchers define previously unknown signaling pathway that triggers inflammation

Using a combination of newly developed methods, researchers led by Ludwig-Maximilians-Universitaet (LMU) in Munich immunologist Veit Hornung have defined a previously unknown pathway that triggers inflammation.

31 Mar 2016

CCCBD offers promising new investigational therapy to treat childhood ALL

The Children's Center for Cancer and Blood Diseases at Children's Hospital Los Angeles is one of the first sites in the world to offer a promising new investigational therapy to treat pediatric acute lymphoblastic leukemia (ALL).

30 Mar 2016

Versatile Automated Microplate Sample Screening Applications

In this interview, News Medical speaks Tobias Pusterla, Ph.D from BMG Labtech about versatile automated microplate sample screening applications.

From BMG LABTECH GmbH 30 Mar 2016

Novel way of hitting prostate cancer

Researchers at UC Davis, in collaboration with the other institutions, have found that suppressing the nuclear receptor protein ROR-γ with small-molecule compounds can reduce androgen receptor (AR) levels in castration-resistant prostate cancer and stop tumor growth.

29 Mar 2016

Lack of ARHGAP33 molecule causes neuropsychiatric disorders-related abnormal higher brain functions

A research group led by Osaka University and the University of Tokyo found that the intracellular protein trafficking is important for higher brain functions such as learning and memory. The research group showed that a molecule, ARHGAP33 regulates synaptic functions and behaviors via intracellular protein trafficking and that the lack of ARHGAP33 causes neuropsychiatric disorder-related impaired higher brain functions.

29 Mar 2016

Osteoporosis drugs market in the US estimated to cross US$ 4 billion by 2021

According to Pharmaion report, "United States Osteoporosis Drugs Market Opportunities, 2011 - 2021", the osteoporosis drugs market in the US is projected to cross US$ 4 billion by 2021.

26 Mar 2016

UC Berkeley biologists discover potential target for unisex contraceptives

UC Berkeley biologists have discovered the switch that triggers the power kick sperm use to penetrate and fertilize a human egg, uncovering a possible source of male infertility but also a potential target for contraceptives that work in both men and women.

26 Mar 2016

Receptor News and Research

Newly developed light-activated tool could pave way for new generation of anti-diabetic drugs

BMPR2 mutations affect outcomes of PAH patients

Flexible ramp scripting interface added for BioScope Resolve BioAFM

AstraZeneca, MedImmune to present new clinical trial and scientific data on lung cancer treatments at ELCC 2016

Metabolic pathway activates cell signaling protein to promote breast cancer metastasis

Ludwig, CRI launch Phase 1/2 trial of combination immunotherapy for advanced ovarian cancer

Immune cell with 'Superman' power could lead to novel therapies for type 1 diabetes

Study explores two new antibodies believed to cause myasthenia gravis

New study shows link between FZD7 protein and breast cancer development

Magnesium could be safe, cost-effective therapeutic intervention for genetic coagulation disorder

Researchers uncover vital clues of how the brain erases long term memories

Purdue University-led researchers determine structure of Zika virus

Naltrexone injections could reduce risk of relapse among opioid dependent individuals

LMU-led researchers define previously unknown signaling pathway that triggers inflammation

CCCBD offers promising new investigational therapy to treat childhood ALL

Versatile Automated Microplate Sample Screening Applications

Novel way of hitting prostate cancer

Lack of ARHGAP33 molecule causes neuropsychiatric disorders-related abnormal higher brain functions

Osteoporosis drugs market in the US estimated to cross US$ 4 billion by 2021

UC Berkeley biologists discover potential target for unisex contraceptives

Breathing New Life into Diagnostics: Plasmion's SICRIT Technology

Discover how SciY empowers scientists

Why use light scattering to analyze proteins and viral vectors?

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