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uPAR may be a promising target for therapy in patients with neuroendocrine neoplasms

A novel PET radiotracer can accurately assess the presence of a biomarker that indicates the level of tumor aggressiveness in neuroendocrine neoplasms (NENs).

28 Sep 2022

Treatment for neurological diseases often no longer effective enough in the later stages

Neurological diseases often begin with an inflammatory process and the degradation of the so-called myelin layer, which surrounds the nerve fibers (axons) like a protective insulating layer.

28 Sep 2022

New modeling technique can help better understand the development of rheumatoid arthritis

A new modeling technique can better predict how bones, cartilage, and cellular tissues will be affected by rheumatoid arthritis in small joints.

28 Sep 2022

New compound triggers the same anti-depressant action as rapidly acting psychedelic drugs

While illegal for recreational use, psychedelic drugs are showing great promise as treatments for severe depression and anxiety, as well as alcohol addiction and other conditions.

28 Sep 2022

Houston Methodist researchers receive CPRIT funding to research two of the most lethal cancers

Two Houston Methodist cancer researchers have been awarded a half million dollars in funding from the Cancer Prevention and Research Institute of Texas to further research two of the most lethal, difficult-to-treat cancers that all-too-often have poor prognoses.

28 Sep 2022

Study finds dimethyl fumarate was not associated with an improvement in clinical outcomes in adults hospitalized with COVID-19

Researchers evaluated the efficacy of the anti-inflammatory drug dimethyl fumarate in treating COVID-19 as part of an early phase, randomized, controlled assessment trial in the UK.

28 Sep 2022

Researchers to use $1 million grant for improving blood cancer diagnosis and treatment

Adelaide researchers will use a $1 million grant to improve the diagnosis and treatment of blood cancers, which kill 16 Australians every day.

28 Sep 2022

Giving immunotherapy before targeted therapy improves survival in patients with advanced melanoma

A clinical trial led by clinicians at Georgetown Lombardi Comprehensive Cancer Center showed a remarkable 20 percent advantage in the two-year overall survival rate for people with advanced melanoma who first received immunotherapy (72 percent survival rate) versus those who initially got targeted therapies (52 percent survival rate).

27 Sep 2022

Metaphors relating to journey, war are commonly used in mental health narratives

Metaphors relating to journey, war and struggles are probably the most frequently used in any area, but particularly so when talking about diseases such as cancer or, more recently, COVID-19.

27 Sep 2022

Feeling hopeless, unhappy, and lonely can increase a person's biological age more than smoking

Molecular damage accumulates and contributes to the development of aging-related frailty and serious diseases.

27 Sep 2022

The antibody response against SARS-CoV-2 in patients pre- and post-infusion with commercial intravenous immunoglobulin products

Researchers comparatively evaluated antibody responses against SARS-CoV-2 among immunodeficient individuals pre- and post-intravenous immunoglobulin product infusions.

27 Sep 2022

Rational treatment strategies for SARS-CoV-2 derived from human pluripotent stem cells models

In a recent study posted to the bioRxiv* preprint server, researchers in Australia explored the molecular mechanisms of the pulmonary and cardiac complications caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection using human stem-cell-derived cardiac and lung cells.

27 Sep 2022

New research model enables scientists to test therapeutics for rare neurodegenerative diseases

For the first time, scientists will be able to test therapeutics for a group of rare neurodegenerative diseases that affect infants and young children thanks to a new research model created by scientists at the University of Wisconsin–Madison.

26 Sep 2022

Novel nanozyme protects bones against damage from radiation

University of Central Florida material sciences engineers Melanie Coathup and Sudipta Seal have designed a cerium oxide nanoparticle - an artificial enzyme - that protects bones against damage from radiation.

26 Sep 2022

Prevention of cardiovascular disease is important in cancer patients

With the increasing number of cancer survivors, the medical community is becoming increasingly aware of a hitherto less noticed health risk: cancer therapy-related cardiovascular disease.

26 Sep 2022

Selectively targeting iGPX4 may be a promising therapeutic strategy for metabolic-associated fatty liver disease

This new article publication from Acta Pharmaceutica Sinica B, discusses targeting a novel inducible GPX4 alternative isoform to alleviate ferroptosis and treat metabolic-associated fatty liver disease.

26 Sep 2022

Study finds remdesivir-resistant version of COVID-19 in renal transplant recipients

Recent studies have shown that patients with weakened immune systems—which enables the virus that causes COVID-19 to remain longer in the body, copy itself, and continually change—may enable the development of new, slightly different versions of the virus (variants).

26 Sep 2022

Antenatal steroid therapy for pregnant women may improve survival among extremely preterm infants

Steroid treatment before birth appears to improve survival and reduce complications among extremely preterm infants, according to a study funded by the National Institutes of Health.

26 Sep 2022

Researchers identify key gene network responsible for severe tooth enamel defects

Mutations in a certain molecule result in severe damage in the structure and mineral composition of tooth enamel in mice, according to a study conducted at the UZH Center of Dental Medicine.

26 Sep 2022

Embedded bias: How medical records sow discrimination

David Confer, a bicyclist and an audio technician, told his doctor he "used to be Ph.D. level" during a 2019 appointment in Washington, D.C. Confer, then 50, was speaking figuratively: He was experiencing brain fog — a symptom of his liver problems. But did his doctor take him seriously? Now, after his death, Confer's partner, Cate Cohen, doesn't think so.

26 Sep 2022

Therapy News and Research

uPAR may be a promising target for therapy in patients with neuroendocrine neoplasms

Treatment for neurological diseases often no longer effective enough in the later stages

New modeling technique can help better understand the development of rheumatoid arthritis

New compound triggers the same anti-depressant action as rapidly acting psychedelic drugs

Houston Methodist researchers receive CPRIT funding to research two of the most lethal cancers

Study finds dimethyl fumarate was not associated with an improvement in clinical outcomes in adults hospitalized with COVID-19

Researchers to use $1 million grant for improving blood cancer diagnosis and treatment

Giving immunotherapy before targeted therapy improves survival in patients with advanced melanoma

Metaphors relating to journey, war are commonly used in mental health narratives

Feeling hopeless, unhappy, and lonely can increase a person's biological age more than smoking

The antibody response against SARS-CoV-2 in patients pre- and post-infusion with commercial intravenous immunoglobulin products

Rational treatment strategies for SARS-CoV-2 derived from human pluripotent stem cells models

New research model enables scientists to test therapeutics for rare neurodegenerative diseases

Novel nanozyme protects bones against damage from radiation

Prevention of cardiovascular disease is important in cancer patients

Selectively targeting iGPX4 may be a promising therapeutic strategy for metabolic-associated fatty liver disease

Study finds remdesivir-resistant version of COVID-19 in renal transplant recipients

Antenatal steroid therapy for pregnant women may improve survival among extremely preterm infants

Researchers identify key gene network responsible for severe tooth enamel defects

Embedded bias: How medical records sow discrimination

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

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