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Colesevelam HCl hits diabetes with one-two punch

Patients with type 2 diabetes may soon be able to control their glucose and their cholesterol levels with a single drug, according to a study led by Vivian A.

9 Jul 2007

Biomira files NDA for novel inhibitor of hypoxia-inducible factor-1 alpha

Biomira Inc. has announced that it has submitted an investigational new drug (IND) application to the U.S. Food and Drug Administration for PX-478. PX-478 has been shown in preclinical studies to inhibit hypoxia-inducible factor (HIF)-1 alpha, a protein that controls the transcription of a number of genes whose products are important for tumor growth and survival.

4 Jul 2007

Compound found in elderberry could give a natural boost to skin

Forget expensive moisturisers and cosmetic surgery, a compound found in the humble elderberry could give a natural boost to skin.

4 Jul 2007

New diet pill makes you feel full

A new pill developed by Italian scientists expands in the stomach and make dieters feel full.

2 Jul 2007

Mothers' second-hand smoke exposure while pregnant linked to children's ADHD

Children whose mothers were exposed to second-hand smoke while they were pregnant have more symptoms of serious psychological problems compared to the offspring of women who had no prenatal exposure to smoke, according to a new University of Washington study.

28 Jun 2007

Early exposure to iron and later exposure to herbicide paraquat may accelerate age-related neurodegeneration

Exposure to iron during the first weeks of life in combination with exposure later in life to a common herbicide may contribute to the subsequent degeneration of brain cells associated with the onset of Parkinson's disease (PD), according to a new study in mice.

28 Jun 2007

Substance from lapacho tree could lead to new lung-cancer treatment

Researchers at UT Southwestern Medical Center have determined how a substance derived from the bark of the South American lapacho tree kills certain kinds of cancer cells, findings that also suggest a novel treatment for the most common type of lung cancer.

26 Jun 2007

New treatment slows the growth of colon and liver cancers

Leire Garcia Navarro, a researcher at the School of Pharmacy of the University of Navarra, has developed a new treatment which slows the growth of colon and liver cancers.

23 Jun 2007

New compound kills fungal pathogens

A new mechanism to attack hard-to-treat fungal infections has been revealed by scientists from the biotech company Anacor Pharmaceuticals Inc., California, and the European Molecular Biology Laboratory (EMBL) outstation in Grenoble, France.

23 Jun 2007

New drug target for the treatment of Parkinson's disease

Researchers at the MassGeneral Institute for Neurodegenerative Disease (MGH-MIND) have identified a potential new drug target for the treatment of Parkinson's disease and possibly for other degenerative neurological disorders.

23 Jun 2007

EPA wants stronger air quality standards for smog

EPA is proposing to strengthen the nation's air quality standards for ground-level ozone, revising the standards for the first time since 1997.

23 Jun 2007

Novel method of drug delivery to inhibit the growth of prostate cancer cells

Prostate cancer is the second leading cause of cancer-related death for men in the U.S. Present treatments for metastatic prostate cancer (cancer cells that spread to other parts of the body) include hormonal therapy, chemotherapy and radiotherapy, which frequently have serious side effects.

23 Jun 2007

Arpida receives FDA approval to initiate Phase II trial with intravenous iclaprim

Arpida Ltd. has announced that it has received approval from the US Food and Drug Administration for a Phase II trial with intravenous iclaprim in the treatment of patients with hospital-acquired pneumonia (HAP), ventilator-associated pneumonia (VAP) or healthcare-associated pneumonia (HCAP) suspected or confirmed to be due to Gram-positive pathogens.

23 Jun 2007

New treatment slows the growth of colon and liver cancers

A. Navarro, a researcher at the School of Pharmacy of the University of Navarra, has developed a new treatment which slows the growth of colon and liver cancers.

23 Jun 2007

New way to increase stem cells in blood

Researchers at Children's Hospital Boston report finding a new way to increase stem cells in blood, suggesting a possible treatment to help patients who undergo chemotherapy or bone marrow transplant for leukemia and other cancers recover their immune function more quickly.

23 Jun 2007

Bristol-Myers Squibb granted NDA for ixabepilone

Bristol-Myers Squibb has announced that the U.S. Food and Drug Administration (FDA) has accepted, for filing and review, the New Drug Application (NDA) for the investigational compound ixabepilone, an epothilone B analog.

20 Jun 2007

New Rochester program to coordinate patient care, research for patients suffering with brain and spinal tumors

The University of Rochester Medical Center and its Department of Neurosurgery are establishing a new multidisciplinary program to coordinate patient care, research and community outreach efforts for patients suffering with brain and spinal tumors.

8 Jun 2007

In mice, drug protects against diabetes and atherosclerosis

Blocking a single protein with an experimental drug prevented and treated both type 2 diabetes and atherosclerosis in laboratory mice that had been fed unhealthy diets and were genetically predisposed to these common killers, according to an article published online in Nature.

8 Jun 2007

New practical weight loss solution for the obese

Millions of people the world over suffer today from obesity, yet there is no magic bullet that has yet provided a universally accepted solution.

8 Jun 2007

What causes Alzheimer's disease?

Researchers tied the accumulation of the toxic brain protein beta-amyloid to Alzheimer's disease, according to a study reported at the 54th Annual Meeting of SNM, the world's largest society for molecular imaging and nuclear medicine professionals.

5 Jun 2007