Genes News and Research

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New tool aids in the discovery of RNA medicines for undruggable diseases

Imagine trying to throw a bullseye when the dartboard lies buried within a crumpled box. That's the challenge faced by scientists working to make new medicines for some "undruggable" diseases, including a type of metastatic breast cancer.

15 Dec 2020

Genes play a decisive role in cruciate ligament injuries

It has long been known that the choice of shoe, surface and type of sport can all be contributing factors when someone suffers an anterior cruciate ligament rupture. Researchers at Lund University in Sweden have now observed that genes also play a decisive role.

15 Dec 2020

Study provides valuable interaction about animal host and pathogen during pneumococcal infections

Researchers at the University of Maryland School of Medicine published one of the most comprehensive analyses of how genes get expressed during infection (known as a transcriptome). The analyses include three different strains of the bacteria Streptococcus pneumoniae, which causes pneumonia, meningitis, and middle-ear infections.

15 Dec 2020

Hybrid approach reveals details about genes involved in Meier-Gorlin syndrome

Meier-Gorlin syndrome, or MGS, is a rare genetic developmental disorder that causes dwarfism, small ears, a small brain, missing patella and other skeletal abnormalities. In severe cases, MGS results in miscarriages and stillbirths.

14 Dec 2020

New clue to protect neurons and encourage their growth found

Many neurodegenerative conditions, from glaucoma to Alzheimer's disease, are characterized by injury to axons - the long, slender projections that conduct electrical impulses from one nerve cell to another, facilitating cellular communications. Injury to axons often leads to neuronal impairment and cell death.

14 Dec 2020

Research breakthrough dispels concerns that human stem cells contain cancer-causing mutations

Pioneering new research has made a pivotal breakthrough that dispel concerns that human stem cells could contain cancer-causing mutations.

14 Dec 2020

Compound derived from thunder god vine could improve outcomes for pancreatic cancer patients

The results of a pre-clinical study led by researchers at the Translational Genomics Research Institute, an affiliate of City of Hope, suggest how a compound derived from the thunder god vine -- an herb used in China for centuries to treat joint pain, swelling and fever -- is able to kill cancer cells and potentially improve clinical outcomes for patients with pancreatic cancer.

14 Dec 2020

Networks of genes involved in congenital heart disease revealed

Over two million babies, children, and adults in the United States are living with congenital heart disease--a range of birth defects affecting the heart's structure or function.

14 Dec 2020

Huntsman Cancer Institute receives $3 million CDC grant to improve colorectal cancer screening

Huntsman Cancer Institute at the University of Utah has been awarded a five-year, $3 million grant from the Centers for Disease Control and Prevention to improve Utah's colorectal cancer screening rates.

14 Dec 2020

New combination therapy has potential to treat aggressive cancers with common mutations

Scientists have long known that therapies that target the cancer-driving MAPK pathway are only effective in a handful of cancers with specific mutations in a cancer gene called BRAF, and these cancers that initially respond to the therapy often end up developing resistance to the treatment, resulting in relapse for many patients.

14 Dec 2020

Extensive genomic data can improve breast cancer risk assessment

Findings from the FinnGen study encompassing 120,000 women indicate that inherited breast cancer risk should be assessed in an increasingly comprehensive manner.

14 Dec 2020

Emergence of resistant SARS-CoV-2 variant in immunocompromised patient following therapeutic antibody use

The focus is increasingly moving towards vaccine roll-out as the world faces the real possibility of the second year of social and economic restrictions.

14 Dec 2020

Prior T cell immunity to SARS-CoV-2 unlikely to be the result of seasonal coronavirus infection

Scientists have suggested that a proportion of the population have pre-existing immunity to COVID-19 because of T cells primed against SARS-CoV-2 antigens.

14 Dec 2020

Study unlocks some muscle cell secrets

A muscle fiber consists of just one cell, but many nuclei. A team at the MDC led by Professor Carmen Birchmeier has now shown just how varied these nuclei are.

11 Dec 2020

Scientists get closer to finding the genes for maleness in weeds

Scientists are getting closer to finding the genes for maleness in waterhemp and Palmer amaranth, two of the most troublesome agricultural weeds in the U.S.

11 Dec 2020

Research provides new insights into Glioblastoma invasiveness

One of the hallmarks of Glioblastoma (GBM), the most aggressive type of brain cancer, is its high invasive capacity, which leads to its expansion into the normal brain tissue.

11 Dec 2020

Texas Biomed to investigate the effects of cannabinoids on HIV-associated neurocognitive disorder

The National Institutes of Health (NIH) awarded Professor Mahesh Mohan, D.V.M., Ph.D., and collaborators more than $3.5 million over five years to investigate the effects of cannabinoids on Human Immunodeficiency Virus (HIV) associated neurocognitive disorder (HAND).

11 Dec 2020

Researchers to investigate why exercise makes some people healthier than others

Why do some people benefit so much from exercise while others enjoy few health gains or even suffer harm? Does age matter when it comes to exercise's health benefits? Are there "molecular signatures" - sets of genes, proteins and other variables ¬- that reveal the answers?

11 Dec 2020

High-intensity workouts improve heart function, increase work capacity

High-intensity interval training strengthens the heart even more than moderate exercise does. Now researchers have found several answers to what makes hard workouts so effective.

11 Dec 2020

Scientist pinpoints genes that promote the growth of prostate cancer cells

Research by a University of Georgia scientist sheds light on how two genes factor into prostate cancer cells becoming resistant to treatment, providing a potential new target for therapeutics.

11 Dec 2020

Genes News and Research

New tool aids in the discovery of RNA medicines for undruggable diseases

Genes play a decisive role in cruciate ligament injuries

Study provides valuable interaction about animal host and pathogen during pneumococcal infections

Hybrid approach reveals details about genes involved in Meier-Gorlin syndrome

New clue to protect neurons and encourage their growth found

Research breakthrough dispels concerns that human stem cells contain cancer-causing mutations

Compound derived from thunder god vine could improve outcomes for pancreatic cancer patients

Networks of genes involved in congenital heart disease revealed

Huntsman Cancer Institute receives $3 million CDC grant to improve colorectal cancer screening

New combination therapy has potential to treat aggressive cancers with common mutations

Extensive genomic data can improve breast cancer risk assessment

Emergence of resistant SARS-CoV-2 variant in immunocompromised patient following therapeutic antibody use

Prior T cell immunity to SARS-CoV-2 unlikely to be the result of seasonal coronavirus infection

Study unlocks some muscle cell secrets

Scientists get closer to finding the genes for maleness in weeds

Research provides new insights into Glioblastoma invasiveness

Texas Biomed to investigate the effects of cannabinoids on HIV-associated neurocognitive disorder

Researchers to investigate why exercise makes some people healthier than others

High-intensity workouts improve heart function, increase work capacity

Scientist pinpoints genes that promote the growth of prostate cancer cells

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