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Scientists discover how to prevent T cell exhaustion to maintain the fight against cancer

When faced with a formidable foe for months on end, the immune system's T cells begin to tire. Whether fighting a cancer or a chronic infection, they become less effective over time, a phenomenon dubbed "T cell exhaustion" by scientists.

28 Jun 2022

New machine learning method may improve the identification of genes that cause diseases

A new machine learning method to model gene expression levels might improve the identification of genes that cause human diseases, according to a new study by Penn State College of Medicine researchers.

28 Jun 2022

Study identifies critical genes and biological pathways related to COVID-19 myocarditis

Scientists from China have recently deciphered the genetic network and biological mechanisms associated with COVID-19 myocarditis using bioinformatic methods.

28 Jun 2022

Low rates of severe COVID-19 found in patients treated with monoclonal antibodies during delta surge

A study of 10,775 high-risk adult patients during the COVID-19 delta variant surge in late 2021 finds that treatment with one of three anti-spike neutralizing monoclonal antibodies for mild to moderate symptoms led to low rates of severe disease, hospitalization, ICU admission and mortality, according to Mayo Clinic researchers.

28 Jun 2022

Highly antibiotic-resistant strain of MRSA on pigs is capable of rapidly adapting to human hosts

A new study has found that a highly antibiotic-resistant strain of the superbug MRSA – methicillin resistant Staphylococcus aureus – has emerged in livestock in the last 50 years, probably due to widespread antibiotic use in pig farming.

28 Jun 2022

New technique offers higher-precision scRNA-seq data than current technologies

The advent of single-cell RNA sequencing (scRNA-seq) has revolutionized the fields of medicine and biology by providing the ability to study the inner workings of thousands of cells at one go.

28 Jun 2022

Genome analysis of alphacoronavirus and betacoronavirus species from South Korean bats

Researchers performed genomic comparisons between alphacoronaviruses (αCoVs) and betacoronaviruses (βCoVs) originating from South Korean Bats.

28 Jun 2022

Evolution of SARS-CoV-2 genomes based on continuing positive selection

Researchers hypothesized that ongoing positive selection strongly influences SARS-CoV-2 genomes, which plays an important role in shaping the dynamics of the COVID-19 pandemic.

28 Jun 2022

Study opens a door to better understanding the role of viruses in ecology

The first discovery of viruses infecting a group of microbes that may include the ancestors of all complex life has been found, researchers at The University of Texas at Austin report in Nature Microbiology.

27 Jun 2022

Study reveals surprising reasons why cancer cells are often forced to rely on fat imports

Columbia and MIT researchers are revealing the surprising reasons why cancer cells are often forced to rely on fat imports, a finding that could lead to new ways to understand and slow down tumor growth.

27 Jun 2022

Researchers discover a molecular switch that promotes pancreatic cancer metastasis

More than 62,000 people in the United States will be diagnosed with pancreatic cancer by the end of this year, with the vast majority having a deadly and aggressive subtype known as pancreatic ductal adenocarcinoma (PDA).

27 Jun 2022

Studies discover multiple gene variants that contribute to the risk and severity of NAFLD in children

In a pair of overlapping studies, a diverse team of researchers, led by scientists at University of California San Diego School of Medicine, have deepened investigations into the genetic origins of nonalcoholic fatty liver disease (NAFLD) in children, describing multiple gene variants (including some previously unknown) that contribute to the risk of developing NAFLD and gene variants associated with the severity of the liver disease.

27 Jun 2022

APOEε4 may confer increased risk for CTE-related neuropathological outcomes among older adults with repetitive head impacts

How could two individuals who both played football for 10 years and developed CTE have different disease severity? How could some individuals develop dementia in their 50's while other never develop dementia at all? Perhaps the answer lies in their genes.

27 Jun 2022

Study discovers microbial link between Western-style diet and colorectal cancer risk

New research builds the case that a Western-style diet - rich in red and processed meat, sugar and refined grains/carbohydrates - is tied to higher risk of colorectal cancer through the intestinal microbiota. Investigators from Brigham and Women's Hospital with collaborators looked at data from more than 134,000 participants from two U.S.-wide prospective cohort studies.

27 Jun 2022

Genetic News and Research

Scientists discover how to prevent T cell exhaustion to maintain the fight against cancer

New machine learning method may improve the identification of genes that cause diseases

Study identifies critical genes and biological pathways related to COVID-19 myocarditis

Low rates of severe COVID-19 found in patients treated with monoclonal antibodies during delta surge

Highly antibiotic-resistant strain of MRSA on pigs is capable of rapidly adapting to human hosts

New technique offers higher-precision scRNA-seq data than current technologies

Genome analysis of alphacoronavirus and betacoronavirus species from South Korean bats

Evolution of SARS-CoV-2 genomes based on continuing positive selection

Study opens a door to better understanding the role of viruses in ecology

Study reveals surprising reasons why cancer cells are often forced to rely on fat imports

Researchers discover a molecular switch that promotes pancreatic cancer metastasis

Studies discover multiple gene variants that contribute to the risk and severity of NAFLD in children

APOEε4 may confer increased risk for CTE-related neuropathological outcomes among older adults with repetitive head impacts

Study discovers microbial link between Western-style diet and colorectal cancer risk

Simple scan can reveal if people are at increased risk of late-life dementia

Vitamin D supplements show promise to counter the adverse effects of diabetes drug on bone health

Researchers discover electrical wave patterns in the brain related to social behavior

The association between handgrip strength and dementia risk in a UK population of middle-aged adults

Genetic screening results just got harder to handle under new abortion rules

Specific gene mutations may be responsible for how long someone lives with Parkinson's disease

eBook: Using iPSCs models for human disease research and drug discovery eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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