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FDA clears ERYTECH Pharma' IND to start Phase I clinical trial of ERYASP in patients with ALL

ERYTECH Pharma SA announced today that it has received clearance of its Investigational New Drug Application from the United States Food and Drug Administration to initiate a Phase I clinical trial of its product ERYASP, L-asparaginase loaded erythrocytes, in patients 40 years or older with newly diagnosed Acute Lymphoblastic Leukemia.

4 Apr 2013

A new method to kill pathogenic bacteria

Engineering researchers at Rensselaer Polytechnic Institute have developed a new method to kill deadly pathogenic bacteria, including listeria, in food handling and packaging. This innovation represents an alternative to the use of antibiotics or chemical decontamination in food supply systems.

3 Apr 2013

Imbalance between neutrophil elastase and α1-antitrypsin leads to obesity, inflammation

Many recent studies have suggested that obesity is associated with chronic inflammation in fat tissues. Researchers at Sanford-Burnham Medical Research Institute have discovered that an imbalance between an enzyme called neutrophil elastase and its inhibitor causes inflammation, obesity, insulin resistance, and fatty liver disease.

3 Apr 2013

UC Davis scientists find mechanism in metabolized omega-3 fatty acid that helps combat cancer

A team of UC Davis scientists has found that a product resulting from a metabolized omega-3 fatty acid helps combat cancer by cutting off the supply of oxygen and nutrients that fuel tumor growth and spread of the disease.

3 Apr 2013

Texas Tech Professor receives NIH grant to research on leishmaniasis

A Texas Tech University biology professor received a five-year, $1.6 million grant from the National Institutes of Health to study the biochemistry of a microscopic parasite responsible for the tropical disease leishmaniasis in the hope of finding a cure.

2 Apr 2013

Minocycline can help reduce hemorrhagic stroke damage

A new study will help determine if an antibiotic is a partial antidote for the poisonous effect blood has on the brain following a hemorrhagic stroke, researchers say.

2 Apr 2013

N30 Pharmaceuticals presents preclinical data of GSNORi at European Cystic Fibrosis Society meeting

N30 Pharmaceuticals, Inc., a clinical stage, biopharmaceutical company focused on the development of therapies for cystic fibrosis, announced today the presentation of key preclinical data for its novel inhibitors of S-nitrosoglutathione reductase.

2 Apr 2013

Modifiable lifestyle factors may prevent progression of Barrett's-related esophageal cancer

An estimated 20 million Americans have chronic heartburn. About 2 million of these people have Barrett's esophagus, a precancerous condition that affects the tube that carries food from the mouth to the stomach.

2 Apr 2013

Study links mutated histone protein to rare brain stem cancer in children

Most cancer treatments are blunt. In an attempt to eradicate tumors, oncologists often turn to radiation or chemotherapy, which can damage healthy tissue along with the cancerous growths.

2 Apr 2013

Research findings could lead to new targets for treating inflammatory disorders

Researchers at UC Davis have shown how the innate immune system distinguishes between dangerous pathogens and friendly microbes. Like burglars entering a house, hostile bacteria give themselves away by breaking into cells. However, sensing proteins instantly detect the invasion, triggering an alarm that mobilizes the innate immune response.

2 Apr 2013

Sanford-Burnham scientists identify how enzyme PKCzeta suppresses prostate tumor formation

Scientists at Sanford-Burnham Medical Research Institute have identified how an enzyme called PKCζ suppresses prostate tumor formation. The finding, which also describes a molecular chain of events that controls cell growth and metastasis, could lead to novel ways to control disease progression.

2 Apr 2013

LabCorp launches expanded IBD testing profile

Laboratory Corporation of America Holdings announced today the availability of an expanded testing menu to help clinicians diagnose, treat and monitor the course of Inflammatory Bowel Disease.

1 Apr 2013

Scientists identify key molecule responsible for triggering chemical processes in brain

Scientists have identified a key molecule responsible for triggering the chemical processes in our brain linked to our formation of memories. The findings, published in the journal Frontiers in Neural Circuits, reveal a new target for therapeutic interventions to reverse the devastating effects of memory loss.

30 Mar 2013

New technique for vaccine design could prove useful against HIV, other viral strains

A team led by scientists from The Scripps Research Institute (TSRI) and the International AIDS Vaccine Initiative (IAVI) has unveiled a new technique for vaccine design that could be particularly useful against HIV and other fast-changing viruses.

30 Mar 2013

New research shows how metabolism and physiology are connected to diet

Sometimes you just can't resist a tiny piece of chocolate cake. Even the most health-conscious eaters find themselves indulging in junk foods from time to time. New research by scientists at the University of Massachusetts Medical School raises the striking possibility that even small amounts of these occasional indulgences may produce significant changes in gene expression that could negatively impact physiology and health.

30 Mar 2013

AACR recognizes scientists whose contributions to cancer field have extraordinary impact

Five University of California, San Diego scientists and professors are among the first class of the Fellows of the American Association for Cancer Research Academy, created to recognize researchers whose scientific contributions have propelled significant innovation and progress against cancer.

29 Mar 2013

Enzyme News and Research

FDA clears ERYTECH Pharma' IND to start Phase I clinical trial of ERYASP in patients with ALL

A new method to kill pathogenic bacteria

Imbalance between neutrophil elastase and α1-antitrypsin leads to obesity, inflammation

UC Davis scientists find mechanism in metabolized omega-3 fatty acid that helps combat cancer

Texas Tech Professor receives NIH grant to research on leishmaniasis

Minocycline can help reduce hemorrhagic stroke damage

N30 Pharmaceuticals presents preclinical data of GSNORi at European Cystic Fibrosis Society meeting

Modifiable lifestyle factors may prevent progression of Barrett's-related esophageal cancer

Study links mutated histone protein to rare brain stem cancer in children

Research findings could lead to new targets for treating inflammatory disorders

Sanford-Burnham scientists identify how enzyme PKCzeta suppresses prostate tumor formation

LabCorp launches expanded IBD testing profile

Scientists identify key molecule responsible for triggering chemical processes in brain

New technique for vaccine design could prove useful against HIV, other viral strains

New research shows how metabolism and physiology are connected to diet

AACR recognizes scientists whose contributions to cancer field have extraordinary impact

Mindfulness meditation can reduce stress hormone

Study: Heart failure medications highly cost effective in saving lives

Study promises effective treatment for stroke patients

Study indicates link between estrogen and body fat storage

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