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Study: 46% of living kidney transplant donor recipients are minorities

The largest U.S. multicenter study of living kidney transplant donor chains showed that 46 percent of recipients are minorities, a finding that allays previous fears that these groups would be disadvantaged by expansion of the donor pool through this type of exchange process.

20 Sep 2012

Hip implants are more likely to fail in obese people due to thigh size

University of Iowa researchers have determined that thigh size in obese people is a reason their hip implants are more likely to fail.

20 Sep 2012

FDA Oncologic Drugs Advisory Committee to review Celgene’s pomalidomide NDA on Nov. 8

Celgene Corporation today announced the U.S. Food and Drug Administration's (FDA) Oncologic Drugs Advisory Committee will hold a review of the Company's new drug application (NDA) for pomalidomide at its meeting on November 8, 2012.

20 Sep 2012

Endothelial colony-forming cells show promise against inflammatory bowel disease

New research shows that a special population of stem cells found in cord blood has the innate ability to migrate to the intestine and contribute to the cell population there, suggesting the cells' potential to treat inflammatory bowel disease (IBD).

20 Sep 2012

Enrollment complete in Gamida Cell’s NiCord Phase I/II trial for hematological malignancies

Gamida Cell, a leader in adult stem cell expansion technologies and products, announced today that it has completed enrollment for a Phase I/II clinical trial of NiCord, the company's second pipeline product.

20 Sep 2012

FDA warns consumers not to use Intestinomicina for treatment of infectious diarrhea

The U.S. Food and Drug Administration is warning consumers not to use Intestinomicina, a drug product manufactured in El Salvador and marketed as a treatment for infectious diarrhea and acute gastrointestinal infections.

19 Sep 2012

Scientists discover bone abnormalities in rats undergoing chronic lack of sleep

Scientists at the Medical College of Wisconsin, in a team led by Carol Everson, Ph.D., professor of neurology, cell biology, neurobiology and anatomy, have discovered abnormalities in bone and bone marrow in rats undergoing chronic lack of sleep. They discovered abnormalities in serum markers of bone metabolism in sleep-deprived rats, which led them to conduct direct measurements of bone parameters; this time in rats experiencing recurrent sleep restriction during a large portion of their young adulthood.

19 Sep 2012

Alendronate decreases BMD loss in prostate cancer

Weekly administration of oral biphosphonate alendronate could reduce loss of bone mineral density in prostate cancer patients who start androgen-deprivation therapy, show study findings.

19 Sep 2012

MRD monitoring falls short in childhood AML assessment

Measuring treatment response by minimal residual disease monitoring offers no more prognostic value than morphologic analysis in children with acute myeloid leukemia (AML), show study findings.

19 Sep 2012

Study identifies special gene that regulates bone density and bone strength

A big international study has identified a special gene that regulates bone density and bone strength. The gene can be used as a risk marker for fractures and opens up opportunities for preventive medicine against fractures.

19 Sep 2012

Vitamin D deficiency common in critically ill children

Children who are critically ill frequently have low serum levels of vitamin D, report researchers.

18 Sep 2012

Positive data from Aprea’s APR-246 Phase I/II study on blood or prostate cancer

Aprea today announced positive data from a completed Phase I/II clinical study with its investigational drug APR-246. The results from the study have been published in the Journal of Clinical Oncology.

18 Sep 2012

Harris Health System celebrates completion of Smith Clinic

On Sept. 12, Harris Health System celebrated the completion of Smith Clinic, the system's first outpatient specialty facility. The new facility enhances and expands specialty care for patients formerly seen at hospital-based clinics located at Ben Taub Hospital.

18 Sep 2012

Novel classification system could improve management of facial trauma

A novel scoring system based on the “best” elements of four existing systems can successfully differentiate injuries of patients with complex facial fractures, improving discrimination between severe injuries, report UK researchers.

17 Sep 2012

Refinements in gene therapy prove beneficial for ‘bubble babies’

Results from a long-term study published in Blood show that adding a low dose of chemotherapy prior to gene therapy can help improve outcomes in children with adenosine deaminase-deficient severe combined immunodeficiency.

17 Sep 2012

Scientists solve co-crystal structure of human antibody that can neutralize influenza viruses

Scientists from The Scripps Research Institute and Sea Lane Biotechnologies have solved the co-crystal structure of a human antibody that can neutralize influenza viruses in a unique way.

17 Sep 2012

Study compares transcrestal techniques for maxillary sinus floor elevation

For a successful dental implant, the first step for some patients is reconstructive surgery of the jaw. A bone graft to augment the upper jaw can now be achieved by several methods. To assess these methods, their risk of sinus perforation, and the best evaluation technology, researchers put these procedures to the test on 20 human cadaver specimens.

15 Sep 2012

UMDNJ, Proteonomix to conduct UMK-121 Phase 1 trial in end-stage liver disease

Proteonomix, Inc., a biotechnology company focused on developing therapeutics based upon the use of human cells and their derivatives, today announced it has entered into an agreement with Piscataway, N.J.-based University of Medicine and Dentistry of New Jersey (UMDNJ) to conducted a Phase 1 clinical trial with its proprietary, patent-pending mobilization technology UMK-121 in patients with end-stage liver disease (ESLD).

15 Sep 2012

First annual Golden Goose Awards honor eight scientists

Eight scientists, including four Nobel Prize winners, will be honored today with the first annual Golden Goose Awards, celebrating researchers whose seemingly odd or obscure federally funded research turned out to have a significant impact on society. The awardees will be honored at a ceremony on Capitol Hill, where they will receive their awards from a bipartisan group of Members of Congress.

15 Sep 2012