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FDA to review rejected weight loss drug Qnexa

The weight loss pill Qnexa has been once rejected by the FDA over safety concerns. But this Wednesday it will get a second chance before an FDA advisory committee. Qnexa maker Vivus Inc. hopes something might come out of this second chance. The company will be submitting new safety data from patients who took Qnexa for a second year after completing a one-year clinical trial.

21 Feb 2012

Gender nonconformity in childhood leads to increased risk of abuse: Study

According to researchers from Harvard School of Public Health and Children's Hospital Boston, children who do not conform to their gender-expected behaviors and interests are at a higher risk of being abused and facing subsequent traumas. Their work is published in the journal Pediatrics.

21 Feb 2012

The final link in world's longest living-donor kidney transplant chain

A Loyola University Medical Center patient has become the final link in the world's longest living-donor kidney transplant chain.

20 Feb 2012

Deadly flu virus research may be published for the advancement of science but more risk assessment needed says WHO

According to the World Health Organization, the two controversial studies that explain how scientists mutated the H5N1 bird flu virus into a form that could cause a deadly human pandemic will be published only after experts fully assess the risks.

20 Feb 2012

Gender identity disorder linked with mental health risk in children

The first study to characterize a cohort of U.S. children with diagnosed gender identity disorder, led by researchers at Children's Hospital Boston, documents significant mental health risks as children struggle with strong feelings of being born "in the wrong body."

20 Feb 2012

Quit-smoking drug Chantix effective in cocaine and alcohol addiction

Varenicline is unique among anti-addiction medications in the way it affects the brain. Like nicotine, varenicline activates a specific receptor for a neurotransmitter called acetylcholine, but it does so less intensely than the active ingredient of cigarettes does. The net effect is that the drug seems to help by both cutting cravings and making the formerly desired drug less pleasant — without making non-drug pleasures less intense. Alcohol works on the same chemical receptors in the brain as nicotine, and it may enhance the pleasurable effects of smoking.

18 Feb 2012

Slow walk and poor grip may predict dementia and stroke

According to U.S. researchers the speed of a person’s walk may predict the likelihood of developing dementia later in life. They also told a conference that grip strength in middle-age was linked to the chance of a stroke. The scientists said more studies were needed to understand the connection.

18 Feb 2012

Not-for-profit company leads push for automation of Medicaid enrollment process

Venture capitalists and Wall Street have invested millions of dollars to capitalize on the health care industry's burgeoning demand for information technology. But in New York State, the push to automate the Medicaid enrollment process is being led not by a behemoth IT corporation, but by a tiny not-for-profit: the Hudson Center for Health Equity & Quality (Hudson Center). And 2012 is shaping up to be its breakout year.

18 Feb 2012

Semantics in Healthcare and Life Sciences Conference to be held Feb. 22-24

Web scientist and Research Associate Professor Joanne Luciano in the Tetherless World Constellation at Rensselaer Polytechnic Institute is co-chairing the 2012 Semantics in Healthcare and Life Sciences (CSHALS) conference Feb 22-24 in Boston, Mass.

18 Feb 2012

Bill to bar synthetic recreational drugs hits roadblock

A broadly popular bill by Sen. Amy Klobuchar, D-Minn., to outlaw synthetic recreational drugs across the nation has run into an increasingly common obstacle in the U.S. Senate: the objection of a single senator. Klobuchar and two other senators backing similar measures took the unusual step of taking to the Senate floor Wednesday to publicly denounce a "hold" placed on their bills by freshman Kentucky Republican Rand Paul. ... Paul spokeswoman Moira Bagley said he believes "law enforcement of most drug laws can and should be local and state issues."

17 Feb 2012

Low choline intake increases risk of liver scarring in menopausal women with NAFLD

Menopausal women with non-alcoholic fatty liver disease (NAFLD) who don't consume enough of the essential nutrient choline appear to be at higher risk for liver scarring, according to research led by scientists at Johns Hopkins Children's Center.

17 Feb 2012

Female dog owners more physically active during pregnancy

Collaborative research from the WALTHAM- Centre for Pet Nutrition and the University of Liverpool has shown that pregnant women who own dogs are more physically active than those who don't.

17 Feb 2012

Collaborative Cross can help fast-track key discoveries about genetics and disease

A series of 15 scientific papers published this week in the journals of the Genetics Society of America (Genetics and G3: Genes|Genomes|Genetics) put North Carolina at the epicenter of a scientific resource called the Collaborative Cross - a "library" of genetic diversity that scientists believe can help fast-track important discoveries about genetics and disease into new discoveries, tests, and treatments that impact human health.

17 Feb 2012

IKK2 enzyme plays a key role in proliferation of lung cancer cells

Drugs targeting an enzyme involved in inflammation might offer a new avenue for treating certain lung cancers, according to a new study by scientists at the Salk Institute for Biological Studies.

17 Feb 2012

First accurate predictive model to differentiate between dengue fever and dengue hemorrhagic fever

Researchers at the University of Texas Medical Branch have developed the first accurate predictive model to differentiate between dengue fever (DF) and its more severe form, dengue hemorrhagic fever (DHF).

17 Feb 2012

Amylin may lead to severe heart damage in obese and diabetic patients

Severe heart damage in people who are obese and diabetic is linked with a pancreatic hormone called amylin, UC Davis researchers have found.

17 Feb 2012

Exposure to common flame retardant may affect fertility and long-term memory

Mice genetically engineered to be susceptible to autism-like behaviors that were exposed to a common flame retardant were less fertile and their offspring were smaller, less sociable and demonstrated marked deficits in learning and long-term memory when compared with the offspring of normal unexposed mice, a study by researchers at UC Davis has found.

16 Feb 2012

Biochemists determine first crystal structure of an immunoproteasome

Like a shredder, the immunoproteasome cuts down proteins into peptides that are subsequently presented on the cellular surface. The immune system can distinguish between self and nonself peptides and selectively kills cells that due to a viral infection present non-self peptides at their surface. In autoimmune diseases this mechanism is deregulated and the immune system also eliminates uninfected cells by mistake.

16 Feb 2012

National Guard soldiers more likely to develop alcohol-related problems after deployment

Soldiers in the National Guard with no history of alcohol abuse are at significant risk of developing alcohol-related problems during and after deployment, according to a new study published in Drug and Alcohol Dependence journal.

16 Feb 2012

Injury Prevention in Active Youth

Over the past few decades there has been an increase in injury to youth participating in sport. The issue of youth sport injury has become a conundrum because if there is an increase in injury, then subsequently there is usually an increase in participation. With the insurgence of childhood obesity, youth participation in sporting activities has been encouraged.It has been proven that regularly scheduled physical activity is associated with health improvements and reduced incidence of disease.

16 Feb 2012