Gastroenterology News and Research

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Gastroenterology is the branch of medicine where the digestive system and its disorders are studied.

Adding abemaciclib to hormonal therapy reduces recurrence in patients with HR+ HER2- early breast cancer

Adding abemaciclib to hormonal therapy reduces the risk of cancer recurrence by 25% in patients with high-risk early hormone receptor positive (HR+) human epidermal growth factor receptor 2 negative (HER2-) breast cancer, according to results from a study at ESMO 2020.

21 Sep 2020

Study shows lack knowledge about colonoscopy among high-risk patients

Colorectal cancer is the third most common cause of cancer deaths in the United States and advanced colorectal polyps are a major risk factor.

14 Sep 2020

Study identifies gene that could decrease chances of developing alcoholic cirrhosis

Researchers at Indiana University School of Medicine are learning more about how a person's genes play a role in the possibility they'll suffer from alcoholic cirrhosis with the discovery of a gene that could make the disease less likely.

12 Sep 2020

Intestinal grafts grown using stem cells could lead to personalized transplants for children

Pioneering scientists at the Francis Crick Institute, Great Ormond Street Hospital and UCL Great Ormond Street Institute of Child Health have grown human intestinal grafts using stem cells from patient tissue that could one day lead to personalized transplants for children with intestinal failure, according to a study published in Nature Medicine today (Monday 7th September).

10 Sep 2020

Polygenic risk score can predict risk of drug-induced liver injury

Scientists who were working on a way to determine the viability of batches of tiny liver organoids have discovered a testing method that may have far broader implications.

7 Sep 2020

Unique antibody profile differentiates people with non-celiac gluten sensitivity

A new study of the antibodies produced by people with gluten sensitivity may lead to a better way to detect the condition and treat it.

31 Aug 2020

Alarmins are the 'gold' in breast milk

Breast milk strengthens a child's immune system, supporting the intestinal flora. These facts are common knowledge.

28 Aug 2020

Consuming personal fecal microbiome when dieting may limit weight regain, study shows

People who consume frozen microbiome capsules derived from their own feces when dieting may limit their weight regain, according to a new study published in Gastroenterology, conducted by a team of researchers led by researchers at Ben-Gurion University of the Negev.

26 Aug 2020

Painless magnetic stimulation dramatically reduces episodes of fecal incontinence

Painless magnetic stimulation of nerves that regulate muscles in the anus and rectum appears to improve their function and dramatically reduce episodes of fecal incontinence, a debilitating problem affecting about 10% of the population, investigators report.

25 Aug 2020

Health experts provide guidelines on scientific investigation of synbiotics

Chances are you've heard of or even taken probiotics: supplements delivering "good microbes" to the gut, providing a wide range of health benefits. If you're really up on your gut health, you may also be aware of prebiotics: supplements designed to fuel the good microbes already living in our guts.

25 Aug 2020

Leading international scientists advance a new definition of synbiotics

The word 'synbiotic' appears on a growing number of food and supplement products, with synbiotic ingredients showing promise for modulating the community of microbes living in the human gut, while providing a health benefit.

21 Aug 2020

New kirigami-based shoe sole could help mitigate the risks of slips and falls

Losing your balance and falling does not just happen during icy Boston winters. The slip resistance of your shoes can determine how well you walk on different surfaces without losing balance.

20 Aug 2020

Daily cranberry intake could reduce H. pylori infections

A new clinical trial found consuming cranberry juice containing 44 mg of proanthocyanidins (or "PACs") per 240-mL serving twice daily for eight weeks resulted in a 20% reduction in the H. pylori infection rate in Chinese adult participants, when compared to those consuming lower amounts of juice and a placebo.

18 Aug 2020

Neil Bell appointed as Chief Development Officer of Avacta Life Sciences

Avacta Group plc, the developer of Affimer biotherapeutics and reagents, is pleased to announce the appointment of Neil Bell as Chief Development Officer of Avacta Life Sciences with immediate effect. Neil will be responsible for late stage pre-clinical and early clinical development of Avacta’s pipeline of pre|CISION pro-drugs and Affimer immunotherapies.

From Avacta Life Sciences Ltd. 13 Aug 2020

A new device for modeling the human gut’s complex microbiome environment

Several thousand strains of bacteria live in the human gut. Some of these are associated with disease, while others have beneficial effects on human health.

6 Aug 2020

Study looks into specific site gastric cancer risks among ethnic populations

Non-white Americans, especially Asian Americans, are at disproportionately higher risk for gastric cancer compared to non-Hispanic white Americans.

6 Aug 2020

Researchers shed new light on epigenetic changes associated with ADNP syndrome

A study led by the Seaver Autism Center for Research and Treatment at Mount Sinai found that two different blood epigenetic signatures associated with ADNP syndrome (also known as Helsmoortel-Van Der Aa syndrome) have only a modest correlation with clinical manifestations of the syndrome. The study results were published online August 5 in the American Journal of Human Genetics.

6 Aug 2020

European Commission approves first drug for hepatitis D

What started off as basic research 25 years ago has now lead to a successfully approved drug: The entry blocker bulevirtide (brand name Hepcludex, formerly known as Myrcludex B), jointly developed by researchers from Heidelberg University Hospital (UKHD) and the Medical Faculty of Heidelberg, the DZIF and other partners, has now been approved by the European Commission.

5 Aug 2020

New computational model can help determine drug viability

About 50% of people who take the drug infliximab for inflammatory bowel diseases, such as Crohn's disease, end up becoming resistant or unresponsive to it.

5 Aug 2020

AGA white paper provides a roadmap for colorectal cancer screening

Fewer people would die of colorectal cancer if health care providers adopted a new model of screening that combines better risk assessment, more options for noninvasive testing and more targeted referrals for colonoscopy.

3 Aug 2020