Malignant News and Research

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A Day in the Life of A Clinical Geneticist

In this interview, we spoke to Dr. Julian Barwell, a clinical geneticist, about his day-to-day roles and responsibilities as well as his career highlights.

17 Dec 2021

Nanoparticle therapeutic can be a potential new approach for treating malignant pleural effusion

Researchers at Wake Forest School of Medicine have discovered that a nanoparticle therapeutic enhances cancer immunotherapy and is a possible new approach in treating malignant pleural effusion (MPE).

16 Dec 2021

Researchers map how the HTLV-1 virus causes a rare leukemia in some people

An international team have mapped how the HTLV-1 virus causes a rare leukemia in some people, providing clues on how to stop it happening.

16 Dec 2021

RENAL nephrometry score may help predict which patients are suitable for nephron-sparing surgery

For most children with renal masses, the standard of care has long been to remove the entire affected kidney- which is the protocol for Wilms tumor, the most common kidney cancer in children.

6 Dec 2021

New machine learning model reduces uncertainty in detection of breast cancer

Breast cancer is the most common cancer with the highest mortality rate. Swift detection and diagnosis diminish the impact of the disease.

1 Dec 2021

Review highlights oncolytic viruses with remarkable ability to destroy cancer cells

With the world still in the grip of a devastating pandemic, it's hard to imagine viruses as something other than hostile enemies to be vanquished.

30 Nov 2021

New safe, painless diagnostic tool for detecting breast cancer

Mammograms are a safe, effective way to detect the presence of breast cancer in women. But doctors recommend most females should start getting mammograms after the age of 40 in part because the procedure involves small doses of ionizing radiation.

30 Nov 2021

Combination of two targeted drugs shows "clinically meaningful" activity in some malignant brain tumors

A combination of two targeted cancer drugs showed unprecedented, "clinically meaningful" activity in patients with highly malignant brain tumors that carried a rare genetic mutation, according to a clinical trial report by investigators from Dana-Farber Cancer Institute.

25 Nov 2021

Researchers analyze live bacteria from cystic lesions that are precursors to pancreatic cancer

Bacteria from the digestive system seem to have the potential to cause damage to pancreatic cells, increasing the risk of malignant tumors.

24 Nov 2021

Study identifies key factor sustaining malignant tumor state

In a study published in Nature Cancer, researchers led by Prof. Cedric Blanpain, WELBIO investigator, Director of the Laboratory of Stem Cells and Cancer and Professor at the Université libre de Bruxelles, Belgium, demonstrated that NR2F2 is an essential regulator of malignant tumor state by controlling cancer stem cell and tumor maintenance in mouse and human cancers.

22 Nov 2021

Examining the effects of malaria parasites on global health

News-Medical speaks to Professor Kevin Baird about his lifelong research into malaria and how another malaria parasite, P. Vivax, is taking a toll on global health.

22 Nov 2021

UCLA-developed new "virtual histology" technology may reduce need for skin biopsies

Instead of surgically removing a sample of skin, sending it to a lab and waiting several days for results, your dermatologist takes pictures of a suspicious-looking lesion and quickly produces a detailed, microscopic image of the skin.

18 Nov 2021

Lef1 gene restricts formation of cancer stem cell niches to suppress colorectal tumor growth

The new research findings help to understand mechanisms that lead to different types of intestinal tumors. They show that the Lef1 gene suppresses the development and growth of colorectal cancer by restricting the formation of cancer stem cell niches.

18 Nov 2021

Study explores the impact of ethnicity on brain tumor survival

White British people who have been diagnosed with a malignant primary brain tumor appear to be more likely to die within one year than patients from at least four other ethnic groups according to a study presented at the NCRI Festival.

9 Nov 2021

Researchers develop model for early prediction of cancer patients' response to immunotherapy

Researchers have developed a model that could predict early on in treatment whether cancer patients will respond to immunotherapy, according to a report published today in eLife.

9 Nov 2021

Targeting Shp2 in oncological treatments appears to worsen the disease

In recent years, much scientific effort and funding has focused on developing drugs that target an enzyme with the unwieldy name of Src homology 2-containing protein tyrosine phosphatase 2 or more briefly, Shp2.

9 Nov 2021

Binghamton professor receives grant to develop a faster, less painful way to diagnose lung nodules

A biomedical engineering professor at Binghamton University, State University of New York has received a $2.4 million grant to develop a faster, less painful way to diagnose malignant solitary pulmonary nodules (SPNs).

9 Nov 2021

Study points to a new, effective treatment option for patients with mesothelioma

Combining the immunotherapy agent durvalumab with the chemotherapy agents pemetrexed and cisplatin or carboplatin may provide a new treatment option for patients who have inoperable pleural mesothelioma, a cancer of the tissues lining the lungs, according to a phase II clinical trial led by researchers at the Johns Hopkins Kimmel Cancer Center and the Bloomberg~Kimmel Institute for Cancer Immunotherapy.

8 Nov 2021

Some immune checkpoint inhibitors can cause serious arrhythmias and myocarditis

Immune checkpoint inhibitors (ICIs) have transformed cancer care by unleashing T-cells to fight tumors, but they can cause serious cardiotoxicities including myocarditis. ICI-induced myocarditis represents a new clinical syndrome because of the novelty and considerable usage of ICIs.

7 Nov 2021

Researchers develop a new test to more easily diagnose medulloblastoma

Researchers at the University of British Columbia and BC Cancer, in partnership with BC Children's Hospital Research Institute, have developed a new test to more easily diagnose medulloblastoma, the most common malignant childhood brain tumor.

1 Nov 2021

Malignant News and Research

A Day in the Life of A Clinical Geneticist

Nanoparticle therapeutic can be a potential new approach for treating malignant pleural effusion

Researchers map how the HTLV-1 virus causes a rare leukemia in some people

RENAL nephrometry score may help predict which patients are suitable for nephron-sparing surgery

New machine learning model reduces uncertainty in detection of breast cancer

Review highlights oncolytic viruses with remarkable ability to destroy cancer cells

New safe, painless diagnostic tool for detecting breast cancer

Combination of two targeted drugs shows "clinically meaningful" activity in some malignant brain tumors

Researchers analyze live bacteria from cystic lesions that are precursors to pancreatic cancer

Study identifies key factor sustaining malignant tumor state

Examining the effects of malaria parasites on global health

UCLA-developed new "virtual histology" technology may reduce need for skin biopsies

Lef1 gene restricts formation of cancer stem cell niches to suppress colorectal tumor growth

Study explores the impact of ethnicity on brain tumor survival

Researchers develop model for early prediction of cancer patients' response to immunotherapy

Targeting Shp2 in oncological treatments appears to worsen the disease

Binghamton professor receives grant to develop a faster, less painful way to diagnose lung nodules

Study points to a new, effective treatment option for patients with mesothelioma

Some immune checkpoint inhibitors can cause serious arrhythmias and myocarditis

Researchers develop a new test to more easily diagnose medulloblastoma

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